1. Alterations in the Liver Fat Fraction Features Examined by Magnetic Resonance Imaging Following Bariatric Surgery: a Self-Controlled Observational Study
- Author
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Lixue Wang, Meng Zhang, Zhongtao Zhang, Kaixin Zhao, Di Cao, Mengyi Li, Han Lv, Yang Liu, Peng Zhang, Na Zeng, Lan Jin, and Zhenghan Yang
- Subjects
medicine.medical_specialty ,Biopsy ,Endocrinology, Diabetes and Metabolism ,Bariatric Surgery ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,Non-alcoholic Fatty Liver Disease ,Liver fat ,medicine ,Humans ,Univariate analysis ,Nutrition and Dietetics ,medicine.diagnostic_test ,Receiver operating characteristic ,business.industry ,Fatty liver ,Magnetic resonance imaging ,medicine.disease ,Magnetic Resonance Imaging ,Obesity ,Obesity, Morbid ,Surgery ,Liver ,030211 gastroenterology & hepatology ,Observational study ,Steatohepatitis ,business - Abstract
Obesity is a worldwide epidemic leading to non-alcoholic fatty liver disease. Alterations in the liver fat fraction (LFF) assessed by MRI following bariatric surgery is a promising feature; however, few studies have been fully elucidated. To determine the alterations in the LFF features following surgery using MRI, to determine the correlation with the clinical non-alcoholic steatohepatitis score (C-NASH score), and to identify the predictive factors for postoperative score changes. Patients (n = 69) underwent MRI to measure the LFF at baseline and 3 months postoperatively. Paired sample t tests were applied to investigate the alterations in the major parameters. Univariate analyses were performed to evaluate the factors predicting C-NASH score changes after surgery. Compared with the baseline levels, the LFF significantly decreased 3 months postoperatively (P
- Published
- 2020