1. Circadian Misalignment Is Negatively Associated with the Anthropometric, Metabolic and Food Intake Outcomes of Bariatric Patients 6 Months After Surgery
- Author
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José Américo Gomides de Sousa, Ana Cristina Tomaz Araújo, Cibele Aparecida Crispim, Luís Augusto Mattar, Maria Carliana Mota, Aline Cunha Carvalho, Luisa Pereira Marot, and Camila Thaís da Costa Assis
- Subjects
Adult ,Male ,medicine.medical_specialty ,Calorie ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Gastric Bypass ,Bariatric Surgery ,030209 endocrinology & metabolism ,Overweight ,Eating ,03 medical and health sciences ,Polyunsaturated fat ,0302 clinical medicine ,Weight loss ,Weight Loss ,medicine ,Humans ,Circadian rhythm ,Nutrition and Dietetics ,business.industry ,Insulin ,Anthropometry ,medicine.disease ,Obesity ,Obesity, Morbid ,Surgery ,Female ,030211 gastroenterology & hepatology ,medicine.symptom ,business - Abstract
Circadian misalignment has been associated with an increased risk of overweight and obesity, as well as changes in metabolic parameters. This study evaluated the association between social jet lag (SJL), a measure of circadian misalignment, and anthropometric, metabolic and food intake outcomes 6 months after bariatric surgery. A total of 122 bariatric patients were included (77% female, aged 33 years (range 28–41); 79.5% underwent Roux-en-Y gastric bypass). Anthropometric, food consumption and SJL were evaluated in the preoperative evaluation and in the third and sixth months after surgery. SJL was calculated based on the absolute difference between the mid-sleep time on weekends and weekdays. Generalised estimating equations and linear regression were performed to evaluate the associations between mean SJL exposure and the outcomes. The interaction between SJL and follow-up time negatively influenced the evolution of weight (p = 0.01), BMI (p = 0.04) and insulin levels (p = 0.01). SJL had an effect on intake of calories (p = 0.001), carbohydrate (p = 0.005) and total (p = 0.007), monounsaturated (p = 0.03) and polyunsaturated fat (p
- Published
- 2020