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Start Over Author "Rankinen, Tuomo" Journal obesity research
15 results on '"Rankinen, Tuomo"'

2. The Human Obesity Gene Map: The 2004 Update

Author

Pérusse, Louis, primary, Rankinen, Tuomo, additional, Zuberi, Aamir, additional, Chagnon, Yvon C., additional, Weisnagel, S. John, additional, Argyropoulos, George, additional, Walts, Brandon, additional, Snyder, Eric E., additional, and Bouchard, Claude, additional

Published
2005
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3. The Human Obesity Gene Map: The 2003 Update

Author

Snyder, Eric E., primary, Walts, Brandon, additional, Pérusse, Louis, additional, Chagnon, Yvon C., additional, Weisnagel, S. John, additional, Rankinen, Tuomo, additional, and Bouchard, Claude, additional

Published
2004
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8. Role of Ghrelin Polymorphisms in Obesity Based on Three Different Studies

Author

Ukkola, Olavi, primary, Ravussin, Eric, additional, Jacobson, Peter, additional, Pérusse, Louis, additional, Rankinen, Tuomo, additional, Tschöp, Matthias, additional, Heiman, Mark L., additional, Leon, Arthur S., additional, Rao, D.C., additional, Skinner, James S., additional, Wilmore, Jack H., additional, Sjöström, Lars, additional, and Bouchard, Claude, additional

Published
2002
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12. The Human Obesity Gene Map: The 2000 Update

Author

Pérusse, Louis, primary, Chagnon, Yvon C., additional, Weisnagel, S. John, additional, Rankinen, Tuomo, additional, Snyder, Eric, additional, Sands, John, additional, and Bouchard, Claude, additional

Published
2001
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15. Effects of beta2-adrenergic receptor gene variants on adiposity: the HERITAGE Family Study.

Author

Garenc C, Pérusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC, and Bouchard C

Subjects
Adipose Tissue, Body Mass Index, Female, Genotype, Humans, Linkage Disequilibrium, Male, Physical Endurance physiology, Polymorphism, Genetic, Skinfold Thickness, Tomography, X-Ray Computed, Black People genetics, Body Composition genetics, Obesity genetics, Receptors, Adrenergic, beta genetics, White People genetics
Abstract

We investigated whether the Arg16Gly and Gln27Glu polymorphisms of the beta2-adrenergic receptor gene were associated with body-fat and fat-distribution phenotypes measured before and in response to a 20-week endurance-training program. BMI, fat mass (FAT), percentage of body fat (%FAT), sum of eight skinfolds (SF8), and abdominal fat areas assessed by computed tomography were measured in adult sedentary white and black participants of the HERITAGE Family Study. Evidence of gene-by-obesity interaction was found in whites for several adiposity phenotypes measured before training. Analyses performed separately in nonobese and obese subjects revealed that obese men carrying the Glu27 allele have lower fat accumulation (BMI, FAT, and %FAT) than noncarriers. Among white obese women, Gly16Gly homozygotes had a lower fat accumulation (BMI, FAT, and SF8) than Arg16Gly and Arg16Arg carriers. In response to endurance training, white women with the Arg16Arg genotype exhibited a greater reduction in BMI, FAT, and %FAT. Results observed in blacks were mostly negative. These results suggest that polymorphisms in the beta2-adrenergic receptor gene influence the amount of body fat in white obese men (Gln27Glu) and women (Arg16Gly), as well as the changes in adiposity in response to endurance training in white women (Arg16Gly).

Published
2003
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