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The article discusses the results of a trial about the effects of high-dose antioxidants on postmenopausal women in the U.S. and Canada. The study found that women taking both hormone therapy and high-dose antioxidant vitamins had the highest death rate compared to women who took nothing. The study also indicated that subjects taking 800 IU vitamin E and 1000 mg vitamin C, had either more or equal progression of their coronary heart disease as measured by angiography.