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Start Over Author "Moio N" Journal nutrition, metabolism and cardiovascular diseases
5 results on '"Moio N"'

4. Elevated blood pressure, cardiometabolic risk and target organ damage in youth with overweight and obesity

Author

Claudia Forziato, Lucia Pacifico, Anita Morandi, Melania Manco, Giuseppina Campana, Claudio Maffeis, Emanuele Miraglia del Giudice, Giuliana Valerio, Giovanni de Simone, Claudio Chiesa, Sandro Loche, Marco Giorgio Baroni, Maria Rosaria Licenziati, Luisa Gilardini, Nicola Moio, Gianluca Tornese, Procolo Di Bonito, Anna Di Sessa, Di Bonito, P., Pacifico, L., Licenziati, M. R., Maffeis, C., Morandi, A., Manco, M., del Giudice, E. M., Di Sessa, A., Campana, G., Moio, N., Baroni, M. G., Chiesa, C., De Simone, G., Valerio, G., Forziato, C., Gilardini, L., Loche, S., and Tornese, G.

Subjects
Carotid Artery Diseases, Male, Pediatric Obesity, Cross-sectional study, Endocrinology, Diabetes and Metabolism, Left ventricular ma, Liver steatosis, Medicine (miscellaneous), Blood Pressure, 030204 cardiovascular system & hematology, Overweight, Adolescents, Body Mass Index, Left ventricular mass, Prehypertension, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Risk Factors, Carotid intima media thickness, Prevalence, Child, Children, Carotid intima media thickne, education.field_of_study, Nutrition and Dietetics, Age Factors, Left Ventricular, Italy, Cardiovascular Diseases, Child, Preschool, Liver steatosi, Elevated blood pressure, Obesity, Adolescent, Cross-Sectional Studies, Female, Humans, Hypertrophy, Left Ventricular, Insulin Resistance, Risk Assessment, medicine.symptom, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Population, 030209 endocrinology & metabolism, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Preschool, education, business.industry, Hypertrophy, medicine.disease, Blood pressure, business, Body mass index
Abstract

Background and aim: To compare cardiometabolic risk profile and preclinical signs of target organ damage in youth with normal and elevated blood pressure (BP), according to the American Academy of Pediatrics (AAP) guidelines. Methods and results: This cross-sectional multicenter study included 2739 youth (5-17 year-old; 170 normal-weight, 610 overweight and 1959 with obesity) defined non hypertensive by the AAP guidelines. Anthropometric, biochemical and liver ultrasound data were available in the whole population; carotid artery ultrasound and echocardiographic assessments were available respectively in 427 and 264 youth. Elevated BP was defined as BP >= 90th to = 120/80 to

Published
2020
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5. Central adiposity and left ventricular mass in obese children

Author

G. Sibilio, P. Di Bonito, Nicola Moio, Claudia Forziato, Carolina Scilla, Eduardo Sanguigno, T. Di Fraia, Luigi Cavuto, Francesco Saitta, Brunella Capaldo, Di Bonito, P, Capaldo, Brunella, Forziato C, Sanguigno, E, Di Fraia, T, Scilla, C, Cavuto, L, Saitta, F, Sibilio, G, and Moio, N.

Subjects
Male, medicine.medical_specialty, Adolescent, Systole, Endocrinology, Diabetes and Metabolism, Diastole, Medicine (miscellaneous), Ventricular Function, Left, Childhood obesity, Body Mass Index, Tissue Doppler echocardiography, Internal medicine, medicine, Humans, Child, Adiposity, Waist-to-height ratio, Nutrition and Dietetics, business.industry, Stepwise regression, medicine.disease, Endocrinology, Blood pressure, Cardiology, Female, Hypertrophy, Left Ventricular, Cardiology and Cardiovascular Medicine, business, Body mass index
Abstract

The impact of central adiposity on left ventricular (LV) mass in childhood obesity has been little explored. This study evaluates whether central obesity influences LV mass and function in obese children.Biochemical, anthropometric and echocardiographic measurements were taken in obese (n=111, mean age 10.6+/-2.5 years) and non-obese children (n=30, mean age 10.8+/-3.0 years). Left ventricular function was analyzed by conventional and tissue Doppler echocardiography. LV mass was calculated according to the Penn convention and indexed for height(2.7) (LVM(i)). The obese group showed increased levels of LVM(i) as compared to the non-obese group (35.7+/-8.5 vs 23.5+/-2.8 g/h(2.7), p0.0001). Among obese children, we observed a significant increase of LVM(i) across tertile of waist-height ratio (WHtR). The subjects identified by the highest tertile of WHtR, as compared to subjects identified by the lowest tertile, showed higher levels of BMI (29.5+/-5.4 vs 31.0+/-5.0 kg/m(2), p0.0001) and LVM(i) (32.1+/-6.5 vs 37.1+/-8.5 g/h(2.7), p0.01). Among obese children a positive correlation (standardized for age and gender) was found between LVM(i) and BMI (r=0.282, p0.01) and WHtR (r=0.334, p0.0001). To analyze the independent predictors of LVM(i), a stepwise linear regression analysis was performed using age, gender, BMI, blood pressure, heart rate, HOMA-IR and WHtR as independent variables. LVM(i) was independently associated only with WHtR (beta=0.309, t=3.238, p=0.002).Obese children show an increased LVM(i) and a preserved LV function. Central adiposity is the major determinant of left ventricular mass.

Published
2008
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