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10 results on '"Micek, Agnieszka"'

2. Proposition of a New POLA Index to Assess the Immunomodulatory Properties of the Diet and Its Relationship with the Gut Microbiota, Using the Example of the Incidence of COVID-19 in a Group of People without Comorbidities

Author

Jagielski, Paweł, primary, Wnęk, Dominika, additional, Łuszczki, Edyta, additional, Bolesławska, Izabela, additional, Micek, Agnieszka, additional, Kozioł-Kozakowska, Agnieszka, additional, Piórecka, Beata, additional, Koczur, Karolina, additional, Jankowska, Katarzyna, additional, Gaździńska, Agata, additional, Turczyńska, Marta, additional, and Kawalec, Paweł, additional

Published
2022
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3. The Effect of Dietary Polyphenols on Vascular Health and Hypertension: Current Evidence and Mechanisms of Action

Author

Grosso, Giuseppe, primary, Godos, Justyna, additional, Currenti, Walter, additional, Micek, Agnieszka, additional, Falzone, Luca, additional, Libra, Massimo, additional, Giampieri, Francesca, additional, Forbes-Hernández, Tamara Y., additional, Quiles, José L., additional, Battino, Maurizio, additional, La Vignera, Sandro, additional, and Galvano, Fabio, additional

Published
2022
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5. Enhanced GIP Secretion in Obesity Is Associated with Biochemical Alteration and miRNA Contribution to the Development of Liver Steatosis

Author

Góralska, Joanna, primary, Raźny, Urszula, additional, Polus, Anna, additional, Dziewońska, Agnieszka, additional, Gruca, Anna, additional, Zdzienicka, Anna, additional, Dembińska-Kieć, Aldona, additional, Solnica, Bogdan, additional, Micek, Agnieszka, additional, Kapusta, Maria, additional, Słowińska-Solnica, Krystyna, additional, and Malczewska-Malec, Małgorzata, additional

Published
2020
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6. High Fat Mixed Meal Tolerance Test Leads to Suppression of Osteocalcin Decrease in Obese Insulin Resistant Subjects Compared to Healthy Adults

Author

Raźny, Urszula, Góralska, Joanna, Zdzienicka, Anna, Gruca, Anna, Zapała, Barbara, Micek, Agnieszka, Dembińska-Kieć, Aldona, Solnica, Bogdan, and Malczewska-Malec, Małgorzata

Subjects
0301 basic medicine, Adult, medicine.medical_specialty, osteocalcin, 030209 endocrinology & metabolism, lcsh:TX341-641, Carbohydrate metabolism, Article, postprandial bone turnover, Bone remodeling, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Internal medicine, insulin resistance, medicine, Humans, Obesity, cardiovascular diseases, Meals, Aged, 2. Zero hunger, Nutrition and Dietetics, biology, Adiponectin, business.industry, nutritional and metabolic diseases, mixed meal tolerance test, Bone formation in obesity, Middle Aged, medicine.disease, Dietary Fats, 030104 developmental biology, Endocrinology, Postprandial, Case-Control Studies, Osteocalcin, biology.protein, Homeostatic model assessment, lipids (amino acids, peptides, and proteins), business, Body mass index, lcsh:Nutrition. Foods and food supply, Food Science
Abstract

Nutrients influence bone turnover. Carboxylated osteocalcin (Gla-OC) participates in bone formation whereas its undercarboxylated form (Glu-OC) acts as a hormone in glucose metabolism. The aim of the study was to determine the responses of Gla-OC, Glu-OC, and total-OC (calculated as the sum of Gla-OC and Glu-OC) to a high fat mixed meal tolerance test (HFMTT) in non-obese (body mass index (BMI) &lt, 30 kg/m2, n = 24) and obese subjects (30 &lt, BMI &lt, 40 kg/m2, n = 70) (both sexes, aged 25&ndash, 65 years). Serum Gla-OC and Glu-OC were measured at baseline as well as at 2 and 6 h during a HFMTT by enzyme-linked immunosorbent assay (ELISA). Baseline Gla-OC, Glu-OC, and total-OC levels were lower in obese individuals compared to non-obese participants (p = 0.037, p = 0.016 and p = 0.005, respectively). The decrease in Gla-OC and total-OC, but not in Glu-OC, concentrations during the HFMTT was suppressed in obese, but not in non-obese controls (p &lt, 0.05, p &lt, 0.01, p = 0.08, respectively). Subjects with the highest homeostatic model assessment for insulin resistance (HOMA-IR) index values had a less pronounced decrease in total-OC compared to patients with values of HOMA-IR index in the 1st quartile (p &lt, 0.05). Net incremental area under Gla-OC inversely correlated with adiponectin (rho = &minus, 0.35, p = 0.001). Increase in insulin sensitivity and adiponectin level in obese subjects could beneficially influence postprandial bone turnover expressed by osteocalcin concentration.

Published
2018
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