1. Dietary Fiber Intake (Supplemental or Dietary Pattern Rich in Fiber) and Diabetic Kidney Disease: A Systematic Review of Clinical Trials
- Author
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Luiza de Azevedo Gross, Mirela Jobim de Azevedo, Luciana Verçoza Viana, and Cláudia Mesquita de Carvalho
- Subjects
Dietary Fiber ,Male ,medicine.medical_specialty ,vegetarian diet ,medicine.medical_treatment ,Renal function ,030209 endocrinology & metabolism ,lcsh:TX341-641 ,Review ,030204 cardiovascular system & hematology ,Kidney ,albuminuria ,Diabetic nephropathy ,03 medical and health sciences ,0302 clinical medicine ,systematic review ,Internal medicine ,Diabetes mellitus ,medicine ,Humans ,Diabetic Nephropathies ,Dialysis ,Glycemic ,glomerular filtration rate ,Clinical Trials as Topic ,Nutrition and Dietetics ,Proteinuria ,business.industry ,diabetic nephropathy ,Middle Aged ,medicine.disease ,Diet ,Clinical trial ,Treatment Outcome ,Dietary Supplements ,Albuminuria ,Female ,medicine.symptom ,business ,lcsh:Nutrition. Foods and food supply ,Food Science - Abstract
Fiber intake is associated with better glycemic control being an important nonpharmacologicaltreatment for diabetes (DM). We hypothesize that a dietary fiber intake can bringbenefits to diabetic kidney disease (DKD), improving renal outcomes. This systematic review aimedto evaluate the effect of dietary fiber (supplemental or dietary pattern rich in fiber) on DKD. Wesearched six databases to identify clinical trials that reported fiber intake and renal outcomes(albuminuria, proteinuria, estimated glomerular filtration rate (eGFR) dialysis) in patients with DM.From 1814 studies, 48 papers were fully evaluated. In the end, seven trials (161 patients, aged 58.3years, 49% females) were included. The studies were organized into three categories (vegetarian,Dietary Approaches to Stop Hypertension (DASH) diet, and fiber supplement), two evaluatedsupplements and five dietary patterns. Vegetarian diet reduced albuminuria in three trials, two inpatients with type 1 DM and one in patients with type 2 DM; and one study demonstrated a change inthe eGFR in type 1 DM. The individual quality of the studies was low/uncertain. A vegetarian dietarypattern may have a beneficial effect on these renal outcomes. However, the individual effect of theintake of fiber on DKD not was possible to be evaluated.
- Published
- 2019