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4. The InterPro Database, 2003 brings increased coverage and new features

Author

Mulder, Nicola J., Apweiler, Rolf, Attwood, Teresa K., Bairoch, Amos, Barrell, Daniel, Bateman, Alex, Binns, David, Biswas, Margaret, Bradley, Paul, Bork, Peer, Bucher, Phillip, Copley, Richard R., Courcelle, Emmanuel, Das, Ujjwal, Durbin, Richard, Falquet, Laurent, Fleischmann, Wolfgang, Griffiths-Jones, Sam, Haft, Daniel, Harte, Nicola, Hulo, Nicolas, Kahn, Daniel, Kanapin, Alexander, Krestyaninova, Maria, Lopez, Rodrigo, Letunic, Ivica, Lonsdale, David, Silventoinen, Ville, Orchard, Sandra E., Pagni, Marco, Peyruc, David, Ponting, Chris P., Selengut, Jeremy D., Servant, Florence, Sigrist, Christian J. A., Vaughan, Robert, and Zdobnov, Evgueni M.

Published
2003

9. The InterPro Database, 2003 brings increased coverage and new features

Author

Emmanuel Courcelle, Teresa K. Attwood, Evgeny M. Zdobnov, Nicolas Hulo, Sandra Orchard, Chris P. Ponting, Margaret Biswas, Sam Griffiths-Jones, Paul Bradley, Ivica Letunic, Robert M. Vaughan, David M. Lonsdale, Richard R. Copley, Marco Pagni, Rodrigo Lopez, Daniel H. Haft, Peer Bork, Jeremy D. Selengut, Nicola Mulder, Ujjwal Das, Wolfgang Fleischmann, Richard Durbin, Laurent Falquet, Rolf Apweiler, Phillip Bucher, Florence Servant, Ville Silventoinen, Alexander Kanapin, Alex Bateman, David Peyruc, Nicola Harte, Christian J. A. Sigrist, Daniel Barrell, Amos Marc Bairoch, Daniel Kahn, David Binns, Maria Krestyaninova, Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Bioinformatique, phylogénie et génomique évolutive (BPGE), Département PEGASE [LBBE] (PEGASE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Bairoch, Amos Marc, Falquet, Laurent, Hulo, Nicolas, Zdobnov, Evgeny, and MDC Library

Subjects
Proteins/chemistry/genetics/metabolism, Repetitive Sequences, Amino Acid, 0106 biological sciences, InterPro, Protein Structure, [SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], Web server, 570 Life Sciences, PROSITE, Biology, computer.software_genre, 01 natural sciences, Repetitive Sequences, 610 Medical Sciences, Medicine, Databases, User-Computer Interface, 03 medical and health sciences, TIGRFAMs, Computer Graphics, Genetics, Animals, Protein Databases, ddc:576, Tertiary Protein Structure, Databases, Protein, Protein Processing, 030304 developmental biology, 0303 health sciences, Database, Protein, Post-Translational, Proteins, Articles, Protein Structure, Tertiary, Amino Acid, Post translational, Cardiovascular and Metabolic Diseases, Amino Acid Repetitive Sequences, Protein processing, Protein signature, Protein Processing, Post-Translational, computer, Tertiary, Post-Translational Protein Processing, Autre (Sciences du Vivant), 010606 plant biology & botany
Abstract

InterPro, an integrated documentation resource of protein families, domains and functional sites, was created in 1999 as a means of amalgamating the major protein signature databases into one comprehensive resource. PROSITE, Pfam, PRINTS, ProDom, SMART and TIGRFAMs have been manually integrated and curated and are available in InterPro for text- and sequence-based searching. The results are provided in a single format that rationalises the results that would be obtained by searching the member databases individually. The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 post-translational modifications. Currently, the combined signatures in InterPro cover more than 74% of all proteins in SWISS-PROT and TrEMBL, an increase of nearly 15% since the inception of InterPro. New features of the database include improved searching capabilities and enhanced graphical user interfaces for visualisation of the data. The database is available via a webserver (http://www.ebi.ac.uk/interpro) and anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro).

Published
2003

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