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Background: Gestational Diabetes Mellitus (GDM) is a common metabolic complication in pregnancy with a broad range of adverse foetal and maternal outcomes if not properly managed. Due to the difficult nature of the Oral glucose tolerance test (OGTT), the utilization of the Glycatedhaemoglobin (HbAlc) test as a simpler and acceptable alternative has been suggested. The aims were to determine the GDM prevalence, the diagnostic accuracy, the optimal cut-off point and the validity of the HbAlc in diagnosing GDM using OGTT as the gold standard in the University of Port Harcourt Teaching Hospital (UPTH). Methodology: This was a prospective cross-sectional study involving a cohort of 250 antenatal attendees at 24-28 weeks of pregnancy in the UPTH from 151 February 2018 - 30,h April 2018. Socio-dcmographic data and results of the OGTT and HbAlc tests were analysed using SPSS 21.0 for windows' statistical software. The area under the Receiver Operating Characteristics (ROC) curve was used to determine the diagnostic accuracy of HbAlc. The Youden index was used to get the optimal cut-off point for HbAlc. The validity of the HbAlc was determined using sensitivity, specificity, positive predictive value and negative predictive value. The P-value at p<0.05 was set as the level of significance. Results: Out of the 250 women, 36 (14.4%) had GDM hence in this study, the GDM prevalence was 14.4%. Area under the curve (AUC) = 0.649; 95% confidence interval: 0.550 - 0.748; p-value = 0.004. The optimal cut-off point for HbAlc was 5.18% with a sensitivity of 63.9%, a specificity of 59.3%, a positive predictive value of 20.9% and a negative predictive value of 90.7%. Conclusion: The HbA 1 c at the Optimal cut-off point of 5.18% in our environment cannot replace the OGTT in the diagnosis of GDM because of its low sensitivity and specificity but will be useful in the screening for GDM because of its high negative predictive value at 24-28 weeks gestation. This will reduce the count of gravidae who undergo the cumbersome OGTT. [ABSTRACT FROM AUTHOR]

Aim: This study aimed to determine the prevalence of episiotomy and postepisiotomy complications and to assess the relationship between the risk factors and postepisiotomy complications in the University of Port Harcourt Teaching Hospital. Methodology: This was a descriptive longitudinal study, in which 403 consecutive women who had episiotomy in the labor ward were recruited for the study. They were followed up and reviewed at the postnatal clinic on the 1st and 6th weeks postdelivery. Data regarding age, marital status, occupation, educational status, address, parity, booking status, postepisiotomy complications, and the associated risk factors were entered adequately into a prestructured pro forma, and statistical analysis was done using statistical software (SPSS for Windows® version 19.0). t-test was used to explore the association of risk factors to postepisiotomy complications. Results: The episiotomy rate was 22.1%. The prevalence of postepisiotomy complications was 52.1%. The mean age of the women was 23.8 (standard deviation ± 3.2) years. Seventy-two (34.3%) patients had perineal pain, which lasted for 72 h or more; 61 (29.1%) had difficulty in walking, while 37 (17.6%) had perineal discomfort. Four (1.9%) had wound infection and only one (0.4%) had wound dehiscence. The development of postepisiotomy complications was not statistically significantly associated with risk factors such as gestational age (T = 1.4, P = 0.1), packed cell volume on admission (T = 1.0, P = 0.2), duration of first stage of labor (T = 0.5, P = 0.1), duration of second stage of labor (T = 0.7, P = 0.3), duration of rupture of fetal membranes (T = 0.8, P = 0.4), delivery repair interval (T = 0.6, P = 0.2), estimated blood loss (T = 0.9, P = 0.2), duration of Sitz bath (T = 1.0, P = 0.2), duration of analgesic (T = 1.2, P = 0.1), duration of antibiotics (T = 1.3, P = 0.1), or the operator who performed or repaired the episiotomy (P = 0.2). Conclusion: The prevalence of episiotomy and postepisiotomy complications in this study was high. Necessary attention should be given to ensure adequate pain relief for all parturients who had episiotomy, and the policy of restrictive use of episiotomy should be fully implemented in the department in line with the best practices and evidence-based recommendations. This will further reduce the incidence of episiotomy rate as well complications that may arise from it and ensure a positive pregnancy experience for pregnant women. [ABSTRACT FROM AUTHOR]