1. New ω-phthalimidoperoxyalkanoic acids in decontamination. Destruction of some toxic organophosphorus and organosulfur pollutants
- Author
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Gilbert Magnaud, Gérard Delmas, Louis Da Conceicao, and C. Lion
- Subjects
Pollutant ,chemistry.chemical_classification ,Chemical Warfare Agents ,Paraoxon ,Sulfide ,Stereochemistry ,Chemistry ,General Chemistry ,Human decontamination ,Medicinal chemistry ,Catalysis ,Materials Chemistry ,medicine ,Organosulfur compounds ,medicine.drug - Abstract
Chemical decontamination of toxic compounds (chemical warfare agents and/or insecticides) is of increasing importance. In this study, we report the use of ω-phthalimidoperoxyalkanoic acids 2 in the destruction of paraoxon (O,O-diethyl-O-para-nitrophenylphosphate), a well-known insecticide, and 2-chloro-2′-phenyldiethyl sulfide (a half mustard). We show that while all the peroxyacids used in this series allow the destruction of toxic compounds, the length n of the alkanoic side chain is important to the choice of the optimal industrial compound, which is 2d (n = 5). Synthese et reactivite d'une nouvelle serie d'ω-phtalimidoperacides. Application a la destruction de polluants organophosphores et organosoufres. La decontamination chimique de composes toxiques dans les series des organophosphores et organosoufres est d'une grande importance. Nous decrivons ici nos resultats sur la recherche de reactifs susceptibles de detruire des composes dans ces familles de toxiques; il s'agit d'une serie d'acides ω-phtalimidoperalcanoiques 2. Nous rationalisons, optimisons et justifions le choix du meilleur candidat en fonction de la longueur de la chaine alkyle du peracide 2d (n = 5).
- Published
- 2001