1. Limitations of functional neuroimaging for patient selection and surgical planning in glioma surgery
- Author
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Tej D. Azad, Hugues Duffau, Johns Hopkins University School of Medicine [Baltimore], Neurochirurgie [Hôpital Gui de Chauliac], and Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier]
- Subjects
CBV = cerebral blood volume ,MESH: Functional Neuroimaging ,rs-fMRI = resting-state fMRI ,Surgical planning ,Neurosurgical Procedures ,030218 nuclear medicine & medical imaging ,MESH: Glioma ,0302 clinical medicine ,Medicine ,DES = direct electrical stimulation ,Brain Neoplasms ,Glioma surgery ,Glioma ,General Medicine ,Diffusion tensor imaging ,MESH: Brain Neoplasms ,[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,Radiology ,Tractography ,psychological phenomena and processes ,MESH: Diffusion Tensor Imaging ,MESH: Preoperative Care ,medicine.medical_specialty ,Neurological morbidity ,Direct electrical stimulation ,[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery ,behavioral disciplines and activities ,fMRI = functional MRI ,03 medical and health sciences ,Functional neuroimaging ,Preoperative Care ,Humans ,MESH: Patient Selection ,Selection (genetic algorithm) ,Functional MRI ,MESH: Humans ,DTI = diffusion tensor imaging ,business.industry ,Functional Neuroimaging ,Patient Selection ,MESH: Neurosurgical Procedures ,medicine.disease ,nervous system ,Surgery ,Neurology (clinical) ,business ,BOLD = blood oxygen level–dependent ,030217 neurology & neurosurgery ,Diffusion MRI - Abstract
International audience; The optimal surgical management of gliomas requires a balance between surgical cytoreduction and preservation of neurological function. Preoperative functional neuroimaging, such as functional MRI (fMRI) and diffusion tensor imaging (DTI), has emerged as a possible tool to inform patient selection and surgical planning. However, evidence that preoperative fMRI or DTI improves extent of resection, limits neurological morbidity, and broadens surgical indications in classically eloquent areas is lacking. In this review, the authors describe facets of functional neuroimaging techniques that may limit their impact on neurosurgical oncology and critically evaluate the evidence supporting fMRI and DTI for patient selection and operative planning in glioma surgery. The authors also propose alternative applications for functional neuroimaging in the care of glioma patients.
- Published
- 2020
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