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Your search keyword '"Radbruch, Alexander"' showing total 7 results
Start Over Author "Radbruch, Alexander" Journal neuroradiology
7 results on '"Radbruch, Alexander"'

2. Impact of an AI software on the diagnostic performance and reading time for the detection of cerebral aneurysms on time of flight MR-angiography

Author

Lehnen, Nils C., primary, Schievelkamp, Arndt-Hendrik, additional, Gronemann, Christian, additional, Haase, Robert, additional, Krause, Inga, additional, Gansen, Max, additional, Fleckenstein, Tobias, additional, Dorn, Franziska, additional, Radbruch, Alexander, additional, and Paech, Daniel, additional

Published
2024
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4. Estimation of radiation exposure of children undergoing superselective intra-arterial chemotherapy for retinoblastoma treatment: assessment of local diagnostic reference levels as a function of age, sex, and interventional success

Author

Opitz, Marcel, primary, Bos, Denise, additional, Deuschl, Cornelius, additional, Radbruch, Alexander, additional, Zensen, Sebastian, additional, Sirin, Selma, additional, Forsting, Michael, additional, Bechrakis, Nikolaos, additional, Biewald, Eva, additional, Bornfeld, Norbert, additional, Ketteler, Petra, additional, Timmermann, Beate, additional, Stuschke, Martin, additional, Guberina, Maja, additional, Wetter, Axel, additional, Göricke, Sophia, additional, and Guberina, Nika, additional

Published
2020
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5. Feasibility of intra-arterial chemotherapy for retinoblastoma: experiences in a large single center cohort study

Author

Stenzel, Elena, primary, Göricke, Sophia, additional, Temming, Petra, additional, Biewald, Eva, additional, Zülow, Stefan, additional, Göbel, Juliane, additional, Wanke, Isabel, additional, Umutlu, Lale, additional, Kleinschnitz, Christoph, additional, Bornfeld, Norbert, additional, Forsting, Michael, additional, Radbruch, Alexander, additional, and Mönninghoff, Christoph, additional

Published
2019
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6. Estimation of radiation exposure of children undergoing superselective intra-arterial chemotherapy for retinoblastoma treatment: assessment of local diagnostic reference levels as a function of age, sex, and interventional success.

Author

Opitz, Marcel, Bos, Denise, Deuschl, Cornelius, Radbruch, Alexander, Zensen, Sebastian, Sirin, Selma, Forsting, Michael, Bechrakis, Nikolaos, Biewald, Eva, Bornfeld, Norbert, Ketteler, Petra, Timmermann, Beate, Stuschke, Martin, Guberina, Maja, Wetter, Axel, Göricke, Sophia, and Guberina, Nika

Subjects
ANGIOGRAPHY, CANCER chemotherapy, INTRA-arterial injections, PEDIATRICS, RADIATION doses, INTERVENTIONAL radiology, REFERENCE values, RETINOBLASTOMA, ENVIRONMENTAL exposure, RETROSPECTIVE studies, DESCRIPTIVE statistics, KRUSKAL-Wallis Test, CHILDREN
Abstract

Purpose: This study aims to determine local diagnostic reference levels (LDRLs) of intra-arterial chemotherapy (IAC) procedures of pediatric patients with retinoblastoma (RB) to provide data for establishing diagnostic reference levels (DRLs) in pediatric interventional radiology (IR). Methods: In a retrospective study design, LDRLs and achievable dose (AD) were assessed for children undergoing superselective IAC for RB treatment. All procedures were performed at the flat-panel angiography systems (I) ArtisQ biplane (Siemens Healthineers) and (II) Allura Xper (Philips Healthcare). Patients were differentiated according to age (A1: 1–3 months; A2: 4–12 months; A3: 13–72 months; A4: 73 months–10 years; A5: > 10 years), sex, conducted or not-conducted chemotherapy. Results: 248 neurointerventional procedures of 130 pediatric patients (median age 14.5 months, range 5–127 months) with RB (68 unilateral, 62 bilateral) could be included between January 2010 and March 2020. The following diagnostic reference values, AD, and mean values could be determined: (A2) DRL 3.9 Gy cm2, AD 2.9 Gy cm2, mean 3.5 Gy cm2; (A3) DRL 7.0 Gy cm2, AD 4.3 Gy cm2, mean 6.0 Gy cm2; (A4) DRL 14.5 Gy cm2, AD 10.7 Gy cm2, mean 10.8 Gy cm2; (A5) AD 8.8 Gy cm2, mean 8.8 Gy cm2. Kruskal-Wallis-test confirmed a significant dose difference between the examined age groups (A2–A5) (p < 0.001). There was no statistical difference considering sex (p = 0.076) and conducted or not-conducted chemotherapy (p = 0.627). A successful procedure was achieved in 207/248 cases. Conclusion: We report on radiation exposure during superselective IAC of a pediatric cohort at the German Retinoblastoma Referral Centre. Although an IAC formally represents a therapeutic procedure, our results confirm that radiation exposure lies within the exposure of a diagnostic interventional procedure. DRLs for superselective IAC are substantially lower compared with DRLs of more complex endovascular interventions. [ABSTRACT FROM AUTHOR]

Published
2021
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