1. The clinical management of neuromuscular disorders in intensive care
- Author
-
Eelco F. M. Wijdicks and Maxwell S. Damian
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Neuromuscular disease ,Critical Care ,Icu acquired weakness ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,Intensive care ,medicine ,Humans ,Set (psychology) ,Intensive care medicine ,Genetics (clinical) ,business.industry ,Myasthenic crisis ,Disease Management ,Neuromuscular Diseases ,medicine.disease ,Intensive care unit ,030104 developmental biology ,Neurology ,Pediatrics, Perinatology and Child Health ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Life-threatening neuromuscular disorders affect a small, but growing group of patients in the intensive care unit who present special management problems, as well as great therapeutic opportunities. In inflammatory conditions, a cure is often possible, and for chronic, genetic or degenerative conditions, achieving the previous level of function is the target. Neuromuscular experts and intensivists need to cooperate closely to achieve the best possible outcomes. They need to acquire a very specific set of skills, including both a thorough understanding of the mechanics of ventilation as well as familiarity with the diagnostic categories of genetic and of autoimmune diseases. This review of the clinical management of adult neuromuscular disease in the ICU aims to provide an overview of the most important conditions encountered in the ICU and a practical approach to their diagnosis, monitoring, and treatment.
- Published
- 2019