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Start Over Author "Krishna, Vibhor" Journal neuromodulation
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2. List of Contributors of Volume 1

Author

Ackermann, D. Michael, primary, Ajiboye, Abidemi B., additional, Allison, Brendan Z., additional, Barolat, Giancarlo, additional, Bhadra, Narendra, additional, Bhadra, Niloy, additional, Blaha, Charles D., additional, Bouton, Chad E., additional, Bradley, Kerry, additional, Capadona, Jeffrey R., additional, Cogan, Stuart F., additional, Cozzens, Jeffrey W., additional, Cusack, William, additional, D’Haese, Pierre-Francois, additional, Dawant, Benoit M., additional, de Groat, William C., additional, De Ridder, Dirk, additional, Denison, Timothy, additional, Dolce, Jeffery J., additional, Doleys, Daniel M., additional, Donoghue, John P., additional, E. Larsen, Lars, additional, Falowski, Steven M., additional, Foster, Allison, additional, Gauthier, Lynne V., additional, George, Lydia C., additional, Gomez, Christy, additional, Goodman, Amy M., additional, Grill, Warren M., additional, Gross, Robert E., additional, Guan, Yun, additional, Hara, Seth, additional, Harris, James, additional, He, Bin, additional, Herron, Jeffrey A., additional, Hoyen, Harry A., additional, Kaplitt, Michael G., additional, Keith, Michael W., additional, Kent, Alexander R., additional, Kilgore, Kevin L., additional, Kirsch, Robert F., additional, Kocharian, Gary, additional, Konrad, Peter E., additional, Kramer, Jeffery, additional, Krames, Elliot S., additional, Krishna, Vibhor, additional, Lee, Kendall H., additional, Linderoth, Bengt, additional, Ludwig, Kip A., additional, Machado, Andre G., additional, Madineni, Ravichandra, additional, Manker, Steve G., additional, McIntyre, Cameron C., additional, Mogilner, Alon Y., additional, Mortimer, John T., additional, Mosier, Elizabeth M., additional, North, Richard B., additional, Pancrazio, Joseph J., additional, Parker, John L., additional, Peckham, P. Hunter, additional, Pedersen, Nigel P., additional, Peterson, Erik J., additional, Pless, Benjamin, additional, Pulliam, Christopher L., additional, Rezai, Ali R., additional, Richter, Troy A., additional, Riley, Jonathan, additional, Rosenow, Joshua M., additional, Ross, Erika, additional, Sammartino, Francesco, additional, Schalk, Gerwin, additional, Schubauer, Kathryn M., additional, Sharan, Ashwini D., additional, Shellock, Frank G., additional, Shipley, Jane, additional, Shoffstall, Andrew, additional, Simpson, Brian, additional, Slavin, Konstantin V., additional, Stanton-Hicks, Michael, additional, Tai, Changfeng, additional, Taylor, Toacca, additional, Tomasiewicz, Hilarie C., additional, Tyler, Dustin J., additional, Vancamp, Tim, additional, Vanneste, Sven, additional, Vonck, Kristl E.J., additional, W. Clark, Shannon, additional, Weber, Doug, additional, Weiner, Richard L., additional, Wolfson, Michael, additional, Wu, Chengyuan, additional, Ye, Donald Y., additional, Yin, Dali, additional, and Yin, Hang, additional

Published
2018
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4. List of Contributors of Volume 2

Author

Adnan, Al-Kaisy, primary, Alexopoulos, Andreas, additional, Alo, Kenneth M., additional, Alterman, Ron L., additional, Amar, Arun, additional, Andrade, Pablo, additional, Arulkumar, Sailesh, additional, Awad, Ahmed J., additional, Baltuch, Gordon, additional, Barolat, Giancarlo, additional, Barthélemy, Ernest J., additional, Barua, Neil U., additional, Bennett, Maria E., additional, Bentley, Nicole, additional, Bezchlibnyk, Yarema B., additional, Bijanki, Kelly R., additional, Bingaman, William, additional, Boggs, Joseph W., additional, Boon, Paul, additional, Brouwer, Brigitte A., additional, Campos, Lucas W., additional, Caparso, Anthony, additional, Capozzo, Annamaria, additional, Chae, John, additional, Chang, Jin Woo, additional, Cheng, Jennifer, additional, Copenhaver, David, additional, Deer, Timothy R., additional, Deogaonkar, Milind, additional, Dhar, Deepali, additional, Dohmeier, Keeley, additional, Dougherty, Darin D., additional, Durand, Dominique M., additional, Foote, Kelly, additional, Gilligan, Jeffrey, additional, Gill, Steven S., additional, Gonzalez-Martinez, Jorge, additional, Greenberg, Benjamin D., additional, Gross, Robert E., additional, H. Pourfar, Michael, additional, Hamani, Clement, additional, Hayek, Salim M., additional, Holtzheimer, Paul E., additional, Ilfeld, Brian M., additional, Jin, Haiyan, additional, Joosten, Bert, additional, Jung, Na Young, additional, Kim, Chong H., additional, Kim, Young Goo, additional, Klehr, Martin, additional, Koch, Paul, additional, Kohl, Sina, additional, Kopell, Brian H., additional, Kramer, Daniel, additional, Krames, Elliot S., additional, Krishnan, Balu, additional, Krishna, Vibhor, additional, Kuhn, Jens, additional, Kyung-soo Hong, Jason, additional, Leonardo, Kapural, additional, Leong, Michael S., additional, Li, Dianyou, additional, Linninger, Andreas A., additional, Lipsman, Nir, additional, Liu, Charles, additional, Lozano, Andres M., additional, Mackow, Michael, additional, Malinowski, Mark N., additional, Mayberg, Helen S., additional, Mazzone, Paolo, additional, Mehta, Ankit I., additional, Mehta, Vivek, additional, Mills-Joseph, Reversa, additional, Nair, Dileep, additional, North, Richard B., additional, Okun, Michael, additional, Patel, Nikunj K., additional, Patil, Parag G., additional, Pope, Jason E., additional, Poree, Lawrence R., additional, Prager, Joshua P., additional, Raedt, Robrecht, additional, Rasouli, Jonathan J., additional, Rasskazoff, Serge, additional, Rauck, Richard, additional, Reeves, Kevin, additional, Rezai, Ali R., additional, Russin, Jonathan, additional, Sabersky, Abraham, additional, Saulino, Michael, additional, Scarnati, Eugenio, additional, Schu, Stefan, additional, Sharma, Mayur, additional, Shipley, Jane, additional, Shirvalkar, Prasad, additional, Slavin, Konstantin V., additional, Stanton-Hicks, Michael, additional, Stone, Scellig, additional, Stuart, William A., additional, Sun, Bomin, additional, Tangen, Kevin, additional, Tepper, Stewart J., additional, van Kleef, Maarten, additional, Vancamp, Tim, additional, Verrills, Paul, additional, Viselli, Fabio, additional, Visser-Vandewalle, Veerle, additional, Vitale, Flora, additional, Vonck, Kristl, additional, Wang, Tao, additional, Wang, Xuelian, additional, Weiner, Richard L., additional, Widge, Alik S., additional, Wongsarnpigoon, Amorn, additional, Y. Mogilner, Alon, additional, Yaeger, Kurt A., additional, Yaksh, Tony L., additional, Yin, Dali, additional, Zeljic, Kristina, additional, Zhang, Chencheng, additional, and Zhan, Shikun, additional

Published
2018
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7. The Utility of Diffusion Tensor Imaging in Neuromodulation: Moving Beyond Conventional Magnetic Resonance Imaging

Author

Tohyama, Sarasa, Walker, Matthew R., Sammartino, Francesco, Krishna, Vibhor, and Hodaie, Mojgan

Abstract

Conventional targeting methods for neuromodulation therapies are insufficient for visualizing targets along white matter pathways and localizing targets in patient‐specific space. Diffusion tensor imaging (DTI) holds promise for enhancing neuromodulation targeting by allowing detailed visualization of white matter tracts and their connections on an individual level. We review the literature on DTI and neuromodulation, focusing on clinical studies that have utilized DTI tractography for surgical neuromodulation planning. This primarily includes the growing number of studies on tractography‐guided targeting in deep brain stimulation as well as magnetic resonance‐guided focused ultrasound. In this review, we discuss three main topics: 1) an overview of the basic principles of DTI, its metrics, and tractography, 2) the evolution and utility of DTI to better guide neuromodulation targets, and 3) the ability of DTI to investigate structural connectivity and brain networks, and how such a network perspective may be an integral part of identifying new or optimal neuromodulation targets. There is increasing evidence that DTI is superior to conventional targeting methods with respect to improving brain stimulation therapies. DTI has the ability to better define anatomical targets by allowing detailed visualization of white matter tracts and localizing targets based on individual anatomy. Network analyses can lead to the identification of new or optimal stimulation targets based on understanding how target regions are connected. The integration of DTI as part of routine MRI and surgical planning offers a more personalized approach to therapy and may be an important path for the future of neuromodulation.

Published
2020
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8. Reliability of Intraoperative Testing During Deep Brain Stimulation Surgery

Author

Sammartino, Francesco, Rege, Rahul, and Krishna, Vibhor

Abstract

Deep brain stimulation (DBS) is an effective treatment for medically refractory Parkinson's disease (PD). During DBS surgery, intraoperative testing is performed to confirm optimal lead placement by determining the stimulation thresholds for symptom improvement and side effects. However, the reliability of intraoperative testing in predicting distant postoperative thresholds is unknown. In this study, we hypothesized that intraoperative testing reliably estimates postoperative thresholds for both symptom improvement and side effects. We retrospectively analyzed a prospective database with intraoperative and postoperative thresholds for symptom improvement and side effects from a cohort of 66 PD patients who underwent STN DBS. We recorded the stimulation locations relative to the mid‐commissural point. Within‐patient stimulation pairs were generated by clustering the intraoperative stimulation locations closest to the DBS contacts. We computed the distance between stimulation locations and atlas‐based pyramidal tract (PT) and medial lemniscus (ML) masks. A leave‐one‐out cross‐validation analysis was performed to determine the reliability of intraoperative testing in predicting postoperative thresholds while controlling for the distance from the relevant tracks. Intraoperative testing reliably predicted (area under ROC >0.8) postoperative thresholds for tremor and rigidity improvements, as well as stimulation‐induced motor contractions and paresthesias. The reliability was poor for improvement in bradykinesia. Intraoperative testing reliably predicts postoperative thresholds. These results are relevant during the informed consent process and patient counseling for DBS surgery. These will also guide the development of future methods for intraoperative feedback, especially during asleep DBS.

Published
2020
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