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Your search keyword '"Pavese, Nicola"' showing total 17 results
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17 results on '"Pavese, Nicola"'

1. Exploratory Analysis of PASADENA Open-label Extension Evaluating the Effect of Prasinezumab on the Progression of Motor Signs and Symptoms (S30.006)

Author

Pagano, Gennaro, primary, Monnet, Annabelle, additional, Reyes, Adriana, additional, Simuni, Tanya, additional, Postuma, Ronald, additional, Pavese, Nicola, additional, Stocchi, Fabrizio, additional, Smigorski, Krzysztof, additional, Gerbaldo, Valentina, additional, Thomas, Riorge, additional, Svoboda, Hanno, additional, Fontoura, Paulo, additional, Doody, Rachelle, additional, Kerchner, Geoffrey, additional, Brundin, Patrik, additional, Bonni, Azad, additional, Marek, Kenneth, additional, and Nikolcheva, Tania, additional

Published
2024
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3. A 104-week delayed-start analysis of PASADENA (Phase II study evaluating the safety and efficacy of prasinezumab in early Parkinson’s disease) (S16.008)

Author

Pagano, Gennaro, primary, Zanigni, Stefano, additional, Monnet, Annabelle, additional, Taylor, Kirsten I., additional, Hahn, Andrea, additional, Marek, Kenneth, additional, Postuma, Ron, additional, Pavese, Nicola, additional, Stocchi, Fabrizio, additional, Simuni, Tanya, additional, D’Urso, Giulia, additional, Pross, Nathalie, additional, Lindemann, Michael, additional, Svoboda, Hanno, additional, Fontoura, Paulo, additional, Doody, Rachelle, additional, Kerchner, Geoffrey A., additional, Bonni, Azad, additional, and Nikolcheva, Tania, additional

Published
2022
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4. Outcomes of a Prospective, Multicenter International Registry of Deep Brain Stimulation for Parkinson’s Disease (S4.008)

Author

Deuschl, Günther, primary, Jain, Roshini, additional, Wang, Alex, additional, Scholtes, Heleen, additional, Witt, Karsten, additional, Mehdorn, Hubertus, additional, Timmermann, Lars, additional, Visser-Vandewalle, Veerle, additional, Kuhn, Andrea, additional, Schneider, Gerd-Helge, additional, Schnitzler, Alfons, additional, Martin, Esther Suarez San, additional, Seijo, Fernando, additional, Eldridge, Paul, additional, Jibril, Farah, additional, Pötter-Nerger, Monica, additional, Hamel, Wolfgang, additional, Cavallo, Michele, additional, Sensi, Mariachiara, additional, Regidor, Ignacio, additional, Del Alamo, Del Alamo Marta, additional, Volkmann, Jens, additional, Matthies, Cordula, additional, Whone, Alan, additional, Sarangmat, Nagaraja, additional, Pavese, Nicola, additional, Hassin, Sharon, additional, Spiegelmann, Roberto, additional, Fitzgerald, James, additional, Green, Alex, additional, and Vesper, Jan, additional

Published
2017
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14. Brain Monoaminergic Innervation in Parkin Patients.

Author

Pavese, Nicola, Scherfler, Christopher, Khan, Naheed L., Moore, Robert Y., Hotton, Gary, Lees, Andrew J., Quinn, Niall P., Wood, Nicholas W., Brooks, David J., and Piccini, Paola

Published
2006

17. Decreased intestinal acetylcholinesterase in early Parkinson disease: An 11 C-donepezil PET study.

Author

Fedorova TD, Seidelin LB, Knudsen K, Schacht AC, Geday J, Pavese N, Brooks DJ, and Borghammer P

Subjects
Aged, Area Under Curve, Carbon Radioisotopes, Cross-Sectional Studies, Donepezil, Female, Heart diagnostic imaging, Humans, Indans, Kidney diagnostic imaging, Kidney enzymology, Male, Middle Aged, Myocardium enzymology, Pancreas diagnostic imaging, Pancreas enzymology, Piperidines, ROC Curve, Radiopharmaceuticals, Time Factors, Acetylcholinesterase metabolism, Intestines diagnostic imaging, Intestines enzymology, Parkinson Disease diagnostic imaging, Parkinson Disease enzymology, Positron-Emission Tomography
Abstract

Objective: To investigate systemic levels of acetylcholinesterase in early Parkinson disease (PD) with 11 C-donepezil PET, a potential marker of parasympathetic innervation., Methods: This was a cross-sectional study with 19 patients with early-stage PD (disease duration 1.5 ± 0.6 years) and 16 age-matched controls who had clinical assessments, olfaction tests, and 11 C-donepezil PET to measure acetylcholinesterase density in peripheral organs., Results: The patients with PD showed significantly reduced 11 C-donepezil uptake in the small intestine (-14%, p = 0.018), colon (-22%, p < 0.001), and kidneys (-14%, p = 0.028). No difference in myocardial or pancreatic acetylcholinesterase levels was seen., Conclusion: We found significantly decreased 11 C-donepezil signal in the intestine and kidneys of patients with early PD, suggesting that parasympathetic denervation is present early in the disease course., (© 2017 American Academy of Neurology.)

Published
2017
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