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Your search keyword '"Globas C"' showing total 6 results
Start Over Author "Globas C" Journal neurology
6 results on '"Globas C"'

1. The natural history of spinocerebellar ataxia type 1, 2, 3, and 6: A 2-year follow-up study

Author

Jacobi, H., primary, Bauer, P., additional, Giunti, P., additional, Labrum, R., additional, Sweeney, M. G., additional, Charles, P., additional, Durr, A., additional, Marelli, C., additional, Globas, C., additional, Linnemann, C., additional, Schols, L., additional, Rakowicz, M., additional, Rola, R., additional, Zdzienicka, E., additional, Schmitz-Hubsch, T., additional, Fancellu, R., additional, Mariotti, C., additional, Tomasello, C., additional, Baliko, L., additional, Melegh, B., additional, Filla, A., additional, Rinaldi, C., additional, van de Warrenburg, B. P., additional, Verstappen, C. C. P., additional, Szymanski, S., additional, Berciano, J., additional, Infante, J., additional, Timmann, D., additional, Boesch, S., additional, Hering, S., additional, Depondt, C., additional, Pandolfo, M., additional, Kang, J.- S., additional, Ratzka, S., additional, Schulz, J., additional, Tezenas du Montcel, S., additional, and Klockgether, T., additional

Published
2011
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2. Spinocerebellar ataxia types 1, 2, 3, and 6

Author

Schmitz-Hübsch, T., primary, Coudert, M., additional, Bauer, P., additional, Giunti, P., additional, Globas, C., additional, Baliko, L., additional, Filla, A., additional, Mariotti, C., additional, Rakowicz, M., additional, Charles, P., additional, Ribai, P., additional, Szymanski, S., additional, Infante, J., additional, van de Warrenburg, B.P.C., additional, Dürr, A., additional, Timmann, D., additional, Boesch, S., additional, Fancellu, R., additional, Rola, R., additional, Depondt, C., additional, Schöls, L., additional, Zdienicka, E., additional, Kang, J. -S., additional, Döhlinger, S., additional, Kremer, B., additional, Stephenson, D. A., additional, Melegh, B., additional, Pandolfo, M., additional, di Donato, S., additional, du Montcel, S. Tezenas, additional, and Klockgether, T., additional

Published
2008
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3. SCA Functional Index: A useful compound performance measure for spinocerebellar ataxia

Author

Schmitz-Hubsch, T., primary, Giunti, P., additional, Stephenson, D. A., additional, Globas, C., additional, Baliko, L., additional, Sacca, F., additional, Mariotti, C., additional, Rakowicz, M., additional, Szymanski, S., additional, Infante, J., additional, van de Warrenburg, B.P.C., additional, Timmann, D., additional, Fancellu, R., additional, Rola, R., additional, Depondt, C., additional, Schols, L., additional, Zdzienicka, E., additional, Kang, J. -S., additional, Dohlinger, S., additional, Kremer, B., additional, Melegh, B., additional, Filla, A., additional, and Klockgether, T., additional

Published
2008
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4. Scale for the assessment and rating of ataxia: Development of a new clinical scale

Author

Schmitz-Hubsch, T., primary, du Montcel, S. T., additional, Baliko, L., additional, Berciano, J., additional, Boesch, S., additional, Depondt, C., additional, Giunti, P., additional, Globas, C., additional, Infante, J., additional, Kang, J. -S., additional, Kremer, B., additional, Mariotti, C., additional, Melegh, B., additional, Pandolfo, M., additional, Rakowicz, M., additional, Ribai, P., additional, Rola, R., additional, Schols, L., additional, Szymanski, S., additional, van de Warrenburg, B. P., additional, Durr, A., additional, and Klockgether, T., additional

Published
2006
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5. Spinocerebellar ataxia type 5

Author

Bürk, K., primary, Zühlke, C., additional, König, I. R., additional, Ziegler, A., additional, Schwinger, E., additional, Globas, C., additional, Dichgans, J., additional, and Hellenbroich, Y., additional

Published
2004
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6. SCA Functional Index: A useful compound performance measure for spinocerebellar ataxia

Author

T. Schmitz-Hübsch, Paola Giunti, J-S Kang, A. Filla, B.P.C. van de Warrenburg, Thomas Klockgether, C. Globas, S Döhlinger, L. Baliko, Francesco Saccà, Christian Mariotti, Roberto Fancellu, Jon Infante, Chantal Depondt, Rafał Rola, Béla Melegh, Sandra Szymanski, Berry Kremer, E. Zdzienicka, Ludger Schöls, Dagmar Timmann, Maria Rakowicz, D A Stephenson, Schmitz Hübsch, T, Giunti, P, Stephenson, Da, Globas, C, Baliko, L, Sacca', Francesco, Mariotti, C, Rakowicz, M, Szymanski, S, Infante, J, van de Warrenburg, Bp, Timmann, D, Fancellu, R, Rola, R, Depondt, C, Schöls, L, Zdzienicka, E, Kang, J, Döhlinger, S, Kremer, B, Melegh, B, Filla, Alessandro, and Klockgether, T.

Subjects
Male, medicine.medical_specialty, Ataxia, Central nervous system disease, Disability Evaluation, 03 medical and health sciences, 0302 clinical medicine, Degenerative disease, Cognitive neurosciences [UMCN 3.2], Disease severity, Rating scale, 030225 pediatrics, Multicenter trial, Internal medicine, Perception and Action [DCN 1], medicine, Humans, Spinocerebellar Ataxias, Confounding, Middle Aged, medicine.disease, Motor Skills, Spinocerebellar ataxia, Physical therapy, Female, Neurology (clinical), medicine.symptom, Psychology, Functional Neurogenomics [DCN 2], 030217 neurology & neurosurgery
Abstract

Contains fulltext : 71097.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To evaluate the usefulness of functional measures in patients with spinocerebellar ataxia (SCA). METHODS: We assessed three functional measures-8 m walking time (8MW), 9-hole peg test (9HPT), and PATA repetition rate-in 412 patients with autosomal dominant SCA (genotypes 1, 2, 3, and 6) in a multicenter trial. RESULTS: While PATA rate was normally distributed (mean/median 21.7/20.5 per 10 s), the performance times for 8MW (mean/median 10.8/7.5 s) or 9HPT (mean/median 47.2/35.0 s in dominant, 52.2/37.9 s in nondominant hand) were markedly skewed. Possible learning effects were small and likely clinically irrelevant. A composite functional index (SCAFI) was formed after appropriate transformation of subtest results. The Z-scores of each subtest correlated well with the Scale for the Assessment and Rating of Ataxia (SARA), the Unified Huntington's disease Rating Scale functional assessment, and disease duration. Correlations for SCAFI with each of these parameters were stronger (Pearson r = -0.441 to -0.869) than for each subtest alone. Furthermore, SCAFI showed a linear decline over the whole range of disease severity, while 9HPT and 8MW had floor effects with respect to SARA. Analysis of possible confounders showed no effect of genotype or study site and only minor effects of age for 8MW. CONCLUSION: The proposed functional measures and their composite SCAFI have favorable properties to assess patients with spinocerebellar ataxia.

Published
2008

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