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Your search keyword '"Gasperini S."' showing total 4 results
Start Over Author "Gasperini S." Journal neurology
4 results on '"Gasperini S."'

1. Functional changes in Duchenne muscular dystrophy

Author

Mazzone, E., primary, Vasco, G., additional, Sormani, M.P., additional, Torrente, Y., additional, Berardinelli, A., additional, Messina, S., additional, D'Amico, A., additional, Doglio, L., additional, Politano, L., additional, Cavallaro, F., additional, Frosini, S., additional, Bello, L., additional, Bonfiglio, S., additional, Zucchini, E., additional, De Sanctis, R., additional, Scutifero, M., additional, Bianco, F., additional, Rossi, F., additional, Motta, M.C., additional, Sacco, A., additional, Donati, M.A., additional, Mongini, T., additional, Pini, A., additional, Battini, R., additional, Pegoraro, E., additional, Pane, M., additional, Gasperini, S., additional, Previtali, S., additional, Napolitano, S., additional, Martinelli, D., additional, Bruno, C., additional, Vita, G., additional, Comi, G., additional, Bertini, E., additional, and Mercuri, E., additional

Published
2011
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2. Diagnosis of glycogenosis type II

Author

Bembi, B., primary, Cerini, E., additional, Danesino, C., additional, Donati, M. A., additional, Gasperini, S., additional, Morandi, L., additional, Musumeci, O., additional, Parenti, G., additional, Ravaglia, S., additional, Seidita, F., additional, Toscano, A., additional, and Vianello, A., additional

Published
2008
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3. Management and treatment of glycogenosis type II

Author

Bembi, B., primary, Cerini, E., additional, Danesino, C., additional, Donati, M. A., additional, Gasperini, S., additional, Morandi, L., additional, Musumeci, O., additional, Parenti, G., additional, Ravaglia, S., additional, Seidita, F., additional, Toscano, A., additional, and Vianello, A., additional

Published
2008
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4. Functional changes in Duchenne muscular dystrophy: A 12-month longitudinal cohort study

Author

Luisa Politano, Silvia Frosini, MP Sormani, Tiziana Mongini, Enrico Bertini, Adele D'Amico, Angela Berardinelli, Sara Napolitano, Roberta Battini, Eugenio Mercuri, Giacomo P. Comi, Maria Chiara Motta, Maria Benedetta Donati, Stefano C. Previtali, Marika Pane, Serena Gasperini, Flaviana Bianco, Fabio Cavallaro, Luca Doglio, Gianluca Vita, Sonia Messina, Elena Pegoraro, Danilo Martinelli, Angela Sacco, Gessica Vasco, M Scutifero, Luca Bello, Yvan Torrente, Francesca Rossi, E. Zucchini, Cristina Bruno, Elena S. Mazzone, Antonella Pini, R. De Sanctis, S Bonfiglio, Mazzone, E, Vasco, G, Sormani, Mp, Torrente, Y, Berardinelli, A, Messina, S, D’Amico, A, Doglio, L, Politano, L, Cavallaro, F, Frosini, S, Bello, L, Bonfiglio, S, Zucchini, E, De Sanctis, R, Scutifero, M, Bianco, F, Rossi, F, Motta, Mc, Sacco, A, Donati, Ma, Mongini, T, Pini, A, Battini, R, Pegoraro, E, Pane, M, Gasperini, S, Previtali, S, Napolitano, S, Martinelli, D, Bruno, C, Vita, G, Comi, Giancarlo, Bertini, E, and Mercuri, E.

Subjects
Male, medicine.medical_specialty, Pediatrics, Adolescent, Cross-sectional study, Prednisolone, Duchenne muscular dystrophy, Statistics as Topic, Anti-Inflammatory Agents, Walking, Severity of Illness Index, Cohort Studies, Settore MED/39 - NEUROPSICHIATRIA INFANTILE, Pregnenediones, Severity of illness, medicine, Humans, Muscular Dystrophy, Muscular dystrophy, Child, Preschool, business.industry, Reproducibility of Results, drug therapy/physiopathology, Duchenne, medicine.disease, Muscular Dystrophy, Duchenne, Clinical trial, Cross-Sectional Studies, therapeutic use, Child, Preschool, physiology, Ambulatory, Cohort, Disease Progression, Physical therapy, Female, Neurology (clinical), business, Adolescent, Anti-Inflammatory Agents, therapeutic use, Child, Child, Preschool, Cohort Studies, Cross-Sectional Studies, Disease Progression, Female, Humans, Male, Muscular Dystrophy, drug therapy/physiopathology, Prednisolone, therapeutic use, Pregnenediones, therapeutic use, Reproducibility of Results, Severity of Illness Index, Statistics as Topic, Walking, Cohort study
Abstract

Objective: The aim of the study was to assess different outcome measures in a cohort of ambulant boys with Duchenne muscular dystrophy (DMD) over 12 months in order to establish the spectrum of possible changes in relation to age and steroid treatment. Methods: The study is a longitudinal multicentric cohort study. A total of 106 ambulant patients with DMD were assessed using the 6-minute walk test (6MWT) and North Star Ambulatory Assessment (NSAA) at baseline and 12 months. Clinical data including age and steroid treatment were collected. Results: During the 12 months of the study, we observed a mean decline of 25.8 meters in the 6MWT with a SD of 74.3 meters. On NSAA, the mean decline was 2.2 points with a SD of 3.7. Not all the boys with DMD in our cohort showed a decline over the 12 months, with young boys showing some improvement in their 6MWT and NSAA scores up to the age of 7. NSAA and the 6MWT had the highest correlation ( r = 0.52, p Conclusions: This study provides longitudinal data of NSAA and 6MWT over a 12-month period. These data can be useful when designing a clinical trial.

Published
2011

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