Search

Your search keyword '"C. Wessig"' showing total 4 results
Start Over Author "C. Wessig" Journal neurology
4 results on '"C. Wessig"'

1. Creatine monohydrate in DM2/PROMM: a double-blind placebo-controlled clinical study. Proximal myotonic myopathy

Author

C, Schneider-Gold, M, Beck, C, Wessig, A, George, H, Kele, K, Reiners, and K V, Toyka

Subjects
Adult, Male, Muscle Weakness, Hand Strength, Pilot Projects, Middle Aged, Creatine, Treatment Outcome, Double-Blind Method, Dietary Supplements, Humans, Female, Aged, Myotonic Disorders
Abstract

The efficacy and safety of creatine monohydrate (Cr) in patients with myotonic dystrophy type 2/proximal myotonic myopathy were studied in a small placebo-controlled double-blind trial. Twenty patients received either Cr or placebo for 3 months. After 3 months, there were no significant differences of muscle strength as assessed by hand-held dynamometry, testing of maximum grip strength, Medical Research Council scoring, and the Neuromuscular Symptom Score between the two groups. Some measures indicated trends toward mild improvement with Cr. Myalgia improved in two patients.

Published
2003

2. Fascicular hypoglossus nerve lesion.

Author

Nolte I, Wessig C, and Bendszus M

Subjects
Adult, Female, Humans, Hypoglossal Nerve pathology, Tongue innervation, Tongue pathology, Wounds, Penetrating diagnosis, Wounds, Penetrating pathology, Anastomosis, Surgical adverse effects, Facial Nerve surgery, Hypoglossal Nerve surgery, Hypoglossal Nerve Injuries, Magnetic Resonance Imaging, Neuroma, Acoustic surgery, Wounds, Penetrating etiology
Published
2006
Full Text
View/download PDF

3. Neuropathology and binding studies in anti-amphiphysin-associated stiff-person syndrome.

Author

Wessig C, Klein R, Schneider MF, Toyka KV, Naumann M, and Sommer C

Subjects
Aged, Animals, Antigen-Antibody Reactions, Autoantibodies blood, Autoimmune Diseases of the Nervous System etiology, Autoimmune Diseases of the Nervous System pathology, Autoimmune Diseases of the Nervous System therapy, Breast Neoplasms complications, Breast Neoplasms immunology, Carcinoma, Ductal, Breast complications, Carcinoma, Ductal, Breast immunology, Cognition Disorders drug therapy, Cognition Disorders etiology, Cognition Disorders immunology, Cognition Disorders pathology, Combined Modality Therapy, Cyclophosphamide therapeutic use, Disease Progression, Fatal Outcome, Female, Gliosis etiology, Gliosis pathology, Humans, Immunosuppressive Agents therapeutic use, Magnetic Resonance Imaging, Ocular Motility Disorders drug therapy, Ocular Motility Disorders etiology, Ocular Motility Disorders immunology, Ocular Motility Disorders pathology, Paraneoplastic Syndromes etiology, Paraneoplastic Syndromes pathology, Paraneoplastic Syndromes therapy, Plasmapheresis, Rats, Stiff-Person Syndrome etiology, Stiff-Person Syndrome pathology, Stiff-Person Syndrome therapy, Autoantibodies immunology, Autoantigens immunology, Autoimmune Diseases of the Nervous System immunology, Nerve Tissue Proteins immunology, Paraneoplastic Syndromes immunology, Pons pathology, Spinal Cord pathology, Stiff-Person Syndrome immunology
Abstract

The authors report a 71-year-old woman with amphiphysin-associated paraneoplastic stiff-person syndrome, opsoclonus, and encephalopathy. The patient's symptoms temporarily responded to plasmapheresis in parallel with a decline of serum anti-amphiphysin antibody titers. Later, the encephalopathy progressed rapidly and the patient died. Binding studies and the detection of autoantibodies in the patient's CNS as well as the treatment response suggest a pathogenic role of the anti-amphiphysin antibodies.

Published
2003
Full Text
View/download PDF

4. Creatine monohydrate in DM2/PROMM: a double-blind placebo-controlled clinical study. Proximal myotonic myopathy.

Author

Schneider-Gold C, Beck M, Wessig C, George A, Kele H, Reiners K, and Toyka KV

Subjects
Adult, Aged, Creatine adverse effects, Dietary Supplements, Double-Blind Method, Female, Hand Strength, Humans, Male, Middle Aged, Muscle Weakness diagnosis, Muscle Weakness drug therapy, Muscle Weakness etiology, Myotonic Disorders complications, Myotonic Disorders genetics, Pilot Projects, Treatment Outcome, Creatine analogs & derivatives, Creatine therapeutic use, Myotonic Disorders drug therapy
Abstract

The efficacy and safety of creatine monohydrate (Cr) in patients with myotonic dystrophy type 2/proximal myotonic myopathy were studied in a small placebo-controlled double-blind trial. Twenty patients received either Cr or placebo for 3 months. After 3 months, there were no significant differences of muscle strength as assessed by hand-held dynamometry, testing of maximum grip strength, Medical Research Council scoring, and the Neuromuscular Symptom Score between the two groups. Some measures indicated trends toward mild improvement with Cr. Myalgia improved in two patients.

Published
2003
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results