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Your search keyword '"Bonavita, Simona"' showing total 23 results
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23 results on '"Bonavita, Simona"'

1. Assessing association of comorbidities with treatment choice and persistence in MS: A real-life multicenter study

Author

Laroni, Alice, Signori, Alessio, Maniscalco, Giorgia T., Lanzillo, Roberta, Russo, Cinzia Valeria, Binello, Eleonora, Lo Fermo, Salvatore, Repice, Annamaria, Annovazzi, Pietro, Bonavita, Simona, Clerico, Marinella, Baroncini, Damiano, Prosperini, Luca, La Gioia, Sara, Rossi, Silvia, Cocco, Eleonora, Frau, Jessica, Torri Clerici, Valentina, Signoriello, Elisabetta, Sartori, Arianna, Zarbo, Ignazio Roberto, Rasia, Sarah, Cordioli, Cinzia, Cerqua, Raffaella, Di Sapio, Alessia, Lavorgna, Luigi, Pontecorvo, Simona, Barrilà, Caterina, Saccà, Francesco, Frigeni, Barbara, Esposito, Sabrina, Ippolito, Domenico, Gallo, Fabio, and Sormani, Maria Pia

Published
2017
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2. Disability assessment in the Google Maps era: a feasibility study to explore a new clinical opportunity (2381)

Author

Abbadessa, Gianmarco, primary, Lavorgna, Luigi, additional, Iaffaldano, Pietro, additional, Lanzillo, Roberta, additional, Esposito, Sabrina, additional, Ippolito, Domenico, additional, Sparaco, Maddalena, additional, Cepparulo, Simone, additional, Lus, Giacomo, additional, Viterbo, Rosa, additional, Clerico, Marinella, additional, Ragonese, Paolo, additional, Borriello, Giovanna, additional, Signoriello, Elisabetta, additional, Trojano, Maria, additional, Tedeschi, Gioacchino, additional, and Bonavita, Simona, additional

Published
2020
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3. Patterns of regional changes in thalamic shape and volume are related to performance in specific cognitive domains in Multiple Sclerosis (S31.009)

Author

Bisecco, Alvino, primary, Capuano, Rocco, additional, Caiazzo, Giuseppina, additional, D’Ambrosio, Alessandro, additional, Docimo, Renato, additional, Bonavita, Simona, additional, Cirillo, Mario, additional, Russo, Antonio, additional, Trojsi, Francesca, additional, Rocca, Maria Assunta, additional, Tedeschi, Gioacchino, additional, and Gallo, Antonio, additional

Published
2019
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4. Resting-state functional correlates of Social Cognition in Multiple Sclerosis (P5.2-048)

Author

Bisecco, Alvino, primary, Santangelo, Gabriella, additional, Di Nardo, Federica, additional, Docimo, Renato, additional, Altieri, Manuela, additional, Capuano, Rocco, additional, Pappacena, Simona, additional, D’Ambrosio, Alessandro, additional, Bonavita, Simona, additional, Cirillo, Mario, additional, Esposito, Fabrizio, additional, Tedeschi, Gioacchino, additional, and Gallo, Antonio, additional

Published
2019
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6. Parenthood and Multiple Sclerosis: an explorative web-based study. (P4.365)

Author

Lavorgna, Luigi, primary, Esposito, Sabrina, additional, Lanzillo, Roberta, additional, Cocco, Eleonora, additional, Clerico, Marinella, additional, Fenu, Giuseppe, additional, Borriello, Giovanna, additional, De Mercanti, Stefania Federica, additional, Frau, Jessica, additional, Capuano, Rocco, additional, Rosa, Laura, additional, Laroni, Alice, additional, Morra, Vincenzo Brescia, additional, Tedeschi, Gioacchino, additional, and Bonavita, Simona, additional

Published
2018
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8. Cognitive impairment in Multiple Sclerosis: the contribution of cognitive reserve and regional gray matter volumes (P3.365)

Author

Bisecco, Alvino, primary, Santangelo, Gabriella, additional, Trojano, Luigi, additional, Docimo, Renato, additional, Capuano, Rocco, additional, Siciliano, Mattia, additional, d’Ambrosio, Alessandro, additional, Corte, Marida Della, additional, Bonavita, Simona, additional, Tedeschi, Gioacchino, additional, and Gallo, Antonio, additional

Published
2018
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9. ATTENTION AND PROCESSING SPEED PERFORMANCE IN MULTIPLE SCLEROSIS IS MOSTLY RELATED TO THALAMIC VOLUME (P4.344)

Author

Bisecco, Alvino, primary, Stamenova, Svetlana, additional, Caiazzo, Giuseppina, additional, D’Ambrosio, Alessandro, additional, Sacco, Rosaria, additional, Docimo, Renato, additional, Esposito, Sabrina, additional, Cirillo, Mario, additional, Esposito, Fabrizio, additional, Bonavita, Simona, additional, Tedeschi, Gioacchino, additional, and Gallo, Antonio, additional

Published
2017
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10. Efficiency of Medical Oversight on an MS Web Community: A Factorial Analysis (P1.342)

Author

Lavorgna, Luigi, primary, Manuela, De Stefano, additional, Montella, Patrizia, additional, Buonanno, Daniela, additional, Fatemeh, Moshtari, additional, Maniscalco, Giorgia Teresa, additional, Francesco, Rullani, additional, Kyrie, Piscopo, additional, Lanzillo, Roberta, additional, Brescia Morra, Vincenzo, additional, Tedeschi, Gioacchino, additional, and Bonavita, Simona, additional

Published
2016
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11. Switch Strategies in RRMS: A Real-Life Multi Center Study (S24.003)

Author

Sacc, Francesco, primary, Signori, Alessio, additional, Maniscalco, Giorgia Teresa, additional, Lanzillo, Roberta, additional, Lo Fermo, Salvatore, additional, Annovazzi, Pietro, additional, Prosperini, Luca, additional, Cocco, Eleonora, additional, Bonavita, Simona, additional, Torri Clerici, Valentina, additional, Laroni, Alice, additional, Repice, Anna Maria, additional, Zarbo, Ignazio Roberto, additional, Raffaella, Cerqua, additional, Di Sapio, Alessia, additional, Pontecorvo, Simona, additional, Clerico, Marinella, additional, Lavorgna, Luigi, additional, Barrillà, Caterina, additional, Cordioli, Cinzia, additional, Gallo, Fabio, additional, and Sormani, Maria Pia, additional

Published
2016
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13. Fatigue in Multiple Sclerosis: The Contribution of Resting-State Functional Connectivity Reorganization (P4.131)

Author

Bisecco, Alvino, primary, Di Nardo, Federica, additional, Docimo, Renato, additional, Caiazzo, Giuseppina, additional, d'Ambrosio, Alessandro, additional, Sacco, Rosaria, additional, Bonavita, Simona, additional, Cirillo, Mario, additional, Esposito, Fabrizio, additional, Tedeschi, Gioacchino, additional, and Gallo, Antonio, additional

Published
2016
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16. Abnormal White Matter Fraction Predicts Cognitive Dysfunction in Multiple Sclerosis Patients (P6.121)

Author

de Stefano, Manuela, primary, Patti, Francesco, additional, Lavorgna, Luigi, additional, Montella, Patrizia, additional, Messina, Silvia, additional, Clara Grazia, Chisari, additional, Ippolito, Domenico, additional, Lanzillo, Roberta, additional, Salemi, Giuseppe, additional, Valentino, Paola, additional, Coniglio, Gabriella, additional, Buccafusca, Maria, additional, Paolicelli, Damiano, additional, Alessandro, D'Ambrosio, additional, Brescia Morra, Vincenzo, additional, Savettieri, Giovanni, additional, Alfano, Bruno, additional, Gallo, Antonio, additional, Simone, Isabella, additional, Zappia, Mario, additional, Valentina, Panetta, additional, Bonavita, Simona, additional, and Tedeschi, Gioacchino, additional

Published
2014
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18. MRI and Clinical Predictors in Multiple Sclerosis: 9 Year Follow-Up Study (S10.006)

Author

Lavorgna, Luigi, primary, Ippolito, Domenico, additional, Simone, Isabella, additional, D'Ambrosio, Alessandro, additional, Lanzillo, Roberta, additional, Gallo, Antonio, additional, Salemi, Giuseppe, additional, Patti, Francesco, additional, Brescia Morra, Vincenzo, additional, Zappia, Mario, additional, Valentino, Paola, additional, Buccafusca, Maria, additional, Coniglio, Gabriella, additional, Savettieri, Giovanni, additional, Bonavita, Simona, additional, and Tedeschi, Gioacchino, additional

Published
2013
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20. Cortical and subcortical chemical pathology in Alzheimer's disease as assessed by multislice proton magnetic resonance spectroscopic imaging

Author

J.H. Duyn, L. Verhagen Metman, Nicholas J. Patronas, Alessandro Bertolino, G. Di Chiro, T. N. Chase, Simona Bonavita, N. Lundbom, Gioacchino Tedeschi, Tedeschi, Gioacchino, Bertolino, A, Lundbom, N, Bonavita, Simona, Patronas, Nj, Duyn, Jh, Metman, Lv, Chase, Tn, and DI CHIRO, G.

Subjects
Brain Mapping, Pathology, medicine.medical_specialty, medicine.diagnostic_test, Brain, Magnetic resonance imaging, Middle Aged, Creatine, Magnetic Resonance Imaging, Brain mapping, Phosphocreatine, White matter, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Alzheimer Disease, medicine, Humans, Choline, Multislice, Neurology (clinical), Protons, Aged, Phosphocholine
Abstract

Background: Multislice proton magnetic resonance spectroscopic imaging (1H-MRSI) permits the simultaneous acquisition of N-acetylaspartate (NA), choline (Cho), creatine/phosphocreatine (Cre), and lactate (Lac) signal intensities from four 15-mm slices divided into 0.84-ml single-volume elements. NA is inferred to be a neuron-specific molecule, whereas Cho mainly reflects glycerophosphocholine and phosphocholine, compounds involved in phospholipid metabolism. Objective: To assess whether 1H-MRSI could detect a regional pattern of cortical and subcortical involvement in the brain of Alzheimer's disease (AD) patients. Methods: 1H-MRSI was performed in 15 patients with probable AD and 15 age-matched healthy controls. Regions of interest (ROIs) were selected from frontal (FC), temporal (TC), parietal (PC), occipital, and insular cortices, subcortical white matter (WM), and thalamus. Results: In AD patients, we found a significant reduction of NA/Cre in the FC, TC, and PC and a significant reduction of Cho/Cre in the WM. Conclusions: This 1H-MRSI study of AD patients shows a regional pattern of neuronal damage in the associative cortices, as revealed by significant reduction of NA/Cre in the FC, TC, and PC, and regional derangement of phospholipid metabolism, as revealed by significant reduction of Cho/Cre in the WM.NEUROLOGY 1996;47: 696-704

Published
1996

21. Genetic association of alpha2-macroglobulin polymorphisms with AD in southern Italy

Author

Mario Zappia, Aldo Quattrone, Rita Cittadella, Virginia Andreoli, Antonio Gambardella, Simona Bonavita, Ida Manna, Giuseppe Nicoletti, Zappia, M, Cittadella, R, Manna, I, Nicoletti, G, Andreoli, V, Bonavita, Simona, Gambardella, A, and Quattrone, A.

Subjects
Male, Genotype, Population, Apolipoprotein E4, Biology, polymorphism, Apolipoproteins E, Gene Frequency, Polymorphism (computer science), southern Italy, Alzheimer Disease, alpha2 macroglobulin, Odds Ratio, Humans, Genetic Predisposition to Disease, alpha-Macroglobulins, Risk factor, Allele, education, Allele frequency, Genetic association, Aged, Genetics, education.field_of_study, Polymorphism, Genetic, Odds ratio, Alzheimer's disease, predisposition, Italy, Female, Neurology (clinical)
Abstract

The authors investigated the segregation of two polymorphisms of the alpha2-macroglobulin gene (A2M-I/D and A2M-Ile1000Val) in patients with sporadic AD from southern Italy. The A2M-I and A2M-Val1000 alleles were more frequent in cases than in controls, and this effect was independent from the APOE-epsilon4 status as well as from the age at onset of AD. Moreover, subjects carrying the A2M genotype I/I-Val/Val had a threefold increase of risk for AD. These data support a population-based susceptibility for AD linked to A2M polymorphisms.

Published
2002

22. Evidence for neuroaxonal injury in patients with proteolipid protein gene mutations

Author

David F. Moore, Nicholas J. Patronas, Odile Boespflug-Tanguy, A. Virta, Simona Bonavita, K. P. Frei, Gioacchino Tedeschi, Raphael Schiffmann, B. Choi, Bonavita, Simona, Schiffmann, R, Moore, Df, Frei, K, Choi, B, PATRONAS MD, N, Virta, A, BOESPFLUG TANGUY, O, and Tedeschi, Gioacchino

Subjects
Adult, Male, medicine.medical_specialty, Pathology, Proteolipid protein 1, Adolescent, chemical and pharmacologic phenomena, Gene mutation, Biology, medicine.disease_cause, Atrophy, Degenerative disease, immune system diseases, Internal medicine, medicine, Humans, Child, Myelin Proteolipid Protein, Cerebral atrophy, Mutation, Brain Diseases, Leukodystrophy, medicine.disease, Magnetic Resonance Imaging, Axons, nervous system diseases, Myelin proteolipid protein, Endocrinology, lipids (amino acids, peptides, and proteins), Female, Neurology (clinical)
Abstract

The authors used proton MRS to investigate neuropathologic correlates in nine patients with proteolipid protein (PLP) gene mutations who did not show cerebral atrophy on cranial MRI. When compared with 16 age-matched control participants, patients with PLP mutations had significant and widespread decreased brain N-acetyl aspartate, a neuronal marker. The authors conclude that PLP mutations cause neuroaxonal injury, which in turn contributes to the neurologic deficit observed in these patients.

Published
2001

23. Diffuse central neuronal involvement in Fabry disease: a proton MRS imaging study

Author

Raphael Schiffmann, T.K. Banerjee, Gioacchino Tedeschi, Simona Bonavita, A. Virta, Tedeschi, Gioacchino, Bonavita, Simona, Banerjee, Tk, Virta, A, and Schiffmann, R.

Subjects
Adult, Male, Pathology, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Central nervous system, Neuropathology, In vivo, Basal ganglia, medicine, Humans, Vascular disease, business.industry, Brain, Middle Aged, medicine.disease, Fabry disease, Magnetic Resonance Imaging, Hyperintensity, medicine.anatomical_structure, nervous system, Fabry Disease, Female, Neurology (clinical), Protons, Proton mrs, business
Abstract

Background: The in vivo determination of parenchymal involvement is important to evaluate disease burden. Proton MRS imaging (1H-MRSI) permits simultaneous measurement of N-acetylaspartate (NA), a putative neuron-specific molecule, choline-containing compounds, creatine-phosphocreatine, and lactate from four 15-mm slices divided into 0.84-mL single-volume elements.Objective: To assess the cortical and subcortical neuropathology in Fabry disease (FD).Methods: Regions of interest (ROIs) were selected from several cortical and subcortical locations in nine FD patients. Mean ROI metabolite ratios were compared with control values.Results: FD patients showed a widespread pattern of cortical and subcortical NA reduction. Seven patients showed discrete MRI abnormalities consisting of white matter hyperintensities or basal ganglia infarcts.Conclusion: We found diffuse neuronal involvement in FD extending beyond the areas of MRI-visible cerebrovascular abnormalities. 1H-MRSI may become useful in therapeutic trials.

Published
1999

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