1. Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis
- Author
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Yunsun Song, Dongwhane Lee, Dae Chul Suh, Joong-goo Kim, Jae Kyun Kim, Minkyu Han, Hairi Liu, Lingbo Zhao, Eun Hye Kim, Sung Chul Jung, Dong-geun Lee, Hyun Jung Koo, Min-ju Kim, Seunghee Baek, Seon Moon Hwang, Bum Joon Kim, Yeon-Jung Kim, Hong-Jun Cho, Sang Joon Kim, Sang-Beom Jeon, and Jong S. Kim
- Subjects
atherosclerosis ,risk factors ,cerebrovascular circulation ,smoking ,Medicine (General) ,R5-920 ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Purpose Cigarette smoking (CS) is one of the major risk factors of cerebral atherosclerotic disease, however, its level of contribution to extracranial and intracranial atherosclerotic stenosis (ECAS and ICAS) was not fully revealed yet. The purpose of our study was to assess the association of CS to cerebral atherosclerosis along with other risk factors. Materials and Methods All consecutive patients who were angiographically confirmed with severe symptomatic cerebral atherosclerotic disease between January 2002 and December 2012 were included in this study. Multivariate logistic regression analyses were performed to identify risk factors for ECAS and ICAS. Thereafter, CS group were compared to non-CS group in the entire study population and in a propensity-score matched population with two different age-subgroups. Results Of 1709 enrolled patients, 794 (46.5%) had extracranial (EC) lesions and the other 915 (53.5%) had intracranial (IC) lesions. CS group had more EC lesions (55.8% vs. 35.3%, P
- Published
- 2019
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