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Abstract: Several fuzzy c-means based clustering techniques have been developed to tackle many problems in a number of areas such as pattern recognition, image analysis, communication, data mining. Among all, a common use of such a class of clustering algorithms is in the training of radial basis function neural networks (RBFNNs). In this paper, we describe a novel approach to fuzzy clustering, which organizes the data in clusters on the basis of the input data and a ‘prototype’ regression function built, in the output space, as a summation of a number of linear local regression models. This methodology is shown to be effective in the training of RBFNNs leading to improved performance with respect to other clustering algorithms. [Copyright &y& Elsevier]