1. Preoperative evaluation by functional magnetic resonance imaging in patients with dysembryoplastic neuroepithelial tumours: A case series
- Author
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Natalia García-Casares, Francisco Alfaro-Rubio, José Ramón Ramos-Rodríguez, Álvaro Ocaña-Ledesma, Bernarda Márquez-Márquez, Victoria E. Fernández-Sánchez, Guillermo Ibáñez-Botella, Miguel Ángel Arráez-Sánchez, and Pedro J. Serrano-Castro
- Subjects
03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Brain Neoplasms ,Seizures ,Preoperative Care ,Humans ,Glioma ,Child ,Magnetic Resonance Imaging ,030217 neurology & neurosurgery - Abstract
Dysembryoplastic neuroepithelial tumours (DNET) are a type of benign glioneuronal neoplasia of typically temporal location that produce drug-resistant epileptic seizures in children and young adults.This work aims to assess the usefulness of functional magnetic resonance imaging (fMRI) in the preoperative study in four patients with DNET. A Philips Intera 3.0 Tesla magnetic resonance imaging scanner and the Blood-Oxygen-Level-Dependent (BOLD) technique were used to obtain the images, making it possible to locate the eloquent areas for language and motor areas through the application of specific paradigms.In one case the tumour was adjacent to Broca's area, in two cases it coincided with Wernicke's area, in one patient it was1cm from the motor area for the hand and in another close to memory. Only two of the patients were operated on, without postoperative functional deficit. Hemispheric activation contralateral to the tumour suggestive of neuroplasticity was observed in one of the patients.fMRI is a non-invasive method that allows us to assess the proximity of lesions to eloquent areas, which is key in the evaluation of surgical risk. In addition, it allowed the detection of probable neuroplasticity in one case, which guaranteed the success of the surgery.
- Published
- 2019