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5 results on '"Minoru Kawamura"'

1. Intracellular free magnesium of red blood cells in patients with renal disease

Author

Masaru Kanashiro, Minoru Kawamura, Tohru Sanai, Genjiro Kimura, Hiroshi Amemiya, Yuhei Kawano, Teruo Omae, Mono Kuramochi, Masahito Imanishi, and Shunichi Kojima

Subjects
Adult, Male, medicine.medical_specialty, Erythrocytes, Urology, chemistry.chemical_element, Blood Pressure, Disease, urologic and male genital diseases, Adenosine Triphosphate, Reference Values, Internal medicine, medicine, Humans, In patient, Magnesium, business.industry, Middle Aged, Ciclosporin, Kidney Transplantation, Endocrinology, chemistry, Renal transplant, Creatinine, Kidney Failure, Chronic, Female, business, Intracellular, medicine.drug
Abstract

While serum magnesium (Mg) level is increased in patients with end-stage renal disease (ESRD), it is decreased in renal transplant recipients (TR) receiving ciclosporin. This study was performed to examine the cation metabolism of red blood cells (RBC) in these patients. Intracellular free Mg was measured with 31P-nuclear magnetic resonance spectrometry, and ouabain-sensitive sodium (Na) efflux rate (Eos) was measured from the increase in RBC-Na concentration when RBC were incubated in the presence of ouabain. The ouabain-sensitive Na efflux rate constant (ERCos) was obtained by dividing Eos by RBC-Na concentration. RBC free Mg and ERCos were significantly higher in the TR group than in the ESRD group. There was a significant correlation between RBC free Mg and ERCos (r = 0.474, p less than 0.01). These results support the views that the regulation mechanism for intracellular free Mg is different from that for extracellular Mg in patients with renal disease, and intracellular free Mg modulates Na pump activity of RBC.

Published
1992

2. Contents, Vol. 36, 1984

Author

Naoshi Kohrogi, Elisa Minelli Bertazzoni, P. Coruzzi, Rene Pelleya, L. Sánchez-Sicilia, P. Gómez-Fernández, J.S. Pierce, Keiichi Ito, Kimiyoshi Tsuji, Arthur H. Cohen, A.B. Geers, R. Selgas, J.T. Daugirdas, A. da Costa e Suva, Amin A. Nanji, Kazuro Kanatsu, Harry J. Ward, M. D’Amicone, Tetsuya Miyajima, W.J.F. van der Vijgh, Hiroki Tuchida, Takashi Kuwahara, O. Giardini, M.E. Martínez, M. Taccone-Gallucci, R. Lubrano, R. Coppo, C. Canavese, Jerry L. Newton, J.G. Martinelli, J.C. Netelenbos, Giovanni Panzetta, Jugoro Takeuchi, B. Basolo, A. Montero, James R. Oster, F.A.R. Neves, A. Vercellone, German Ramirez, A. Jonash, Hidehiko Kashiwabara, Frank H. Anderson, R.C.J. Ribeiro, E.J. Dorhout Mees, Toshio Doi, G. Ricciardi-Tenore, H. Boichis, D.J. Leehey, P.S.S. Beraldo, B. Seegal, G.P. Segoloni, Satoshi Akabane, C.U. Casciani, Patoula V. Caralis, Carl D. Brueggemeyer, E. Rossi, A. Borghetti, David C. Kem, G. Koren, U. Ruberto, F. Escuin, Minoru Kawamura, D. Bandino, Shigeo Tomura, J.M. Calatrava, L.O. Simpson, L. Musiari, L. Sánchez Agudo, S. Talarico, M. Aladjem, R.H. Albuquerque, P. Lips, Hideo Shishido, Shunichiro Sakurai, A. Novarini, M.J.M. Jongen, Guido O. Perez, S. Lamon, Wayne A. Border, Yoshihiro Hamashima, G. Piccoli, M.R. Bulzomi, I. Silvi, Koichi Ogino, H.A. Koomans, G.P. Campos, T.S. Ing, Hiroyuki Nagai, and J. Militiano

Subjects
Traditional medicine, business.industry, Medicine, business
Published
1984
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3. Diuretic Response of a Second Infusion of Atrial Natriuretic Polypeptide into Anesthetized Dogs

Author

Keiichi Ito, Minoru Kawamura, Yohkazu Matsushima, Shunichi Kojima, and Satoshi Akabane

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Urinary system, Natriuresis, Diuresis, Drug Administration Schedule, Renal Circulation, Excretion, Dogs, Internal medicine, Renin, Carnivora, Animals, Medicine, Kidney, biology, business.industry, Fissipedia, biology.organism_classification, medicine.anatomical_structure, Endocrinology, cardiovascular system, Female, Kallikreins, Diuretic, business, Atrial Natriuretic Factor, hormones, hormone substitutes, and hormone antagonists, Glomerular Filtration Rate, circulatory and respiratory physiology
Abstract

We examined the diuretic effects of a second infusion of atrial natriuretic polypeptide (ANP). Intrarenal infusion of ANP (50 ng X kg-1 X min-1) for 30 min to anesthetized dogs had no significant effect on mean arterial blood pressure (MABP), renal blood flow (RBF) and glomerular filtration rate (GFR), whereas there was an increase in urine flow (V) and urinary excretion of sodium (UNaV) from 7.5 +/- 1.5 to 34.1 +/- 9.4 microliters/g X min, from 0.97 +/- 0.20 to 4.38 +/- 1.32 microEq/g X min, respectively. When the same dose of ANP was infused 1 h after the first administration, V and UNaV were increased from 12.4 +/- 1.8 to 62.5 +/- 18.8 microliters/g X min, from 1.72 +/- 0.57 to 7.18 +/- 2.68 microEq/g X min, respectively. A second infusion of ANP caused a greater absolute increase in UNaV than did the first infusion but proportionally the increase in UNaV with the second ANP infusion was much the same. The present study shows that acute ANP infusion has no tachyphylaxis on the natriuretic response. These data will aid in establishing a bioassay for natriuretic response in vivo, thereby leading to elucidation of the physiological action of ANP.

Published
1987
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4. Intrarenal beta-adrenergic stimulation enhances excretion of urinary lysosomal enzyme in anesthetized dogs

Author

Keiichi Ito, Satoshi Akabane, Koichi Ogino, and Minoru Kawamura

Subjects
Male, medicine.medical_specialty, Urinary system, Adrenergic, Renal function, Propranolol, urologic and male genital diseases, Kidney, Renal Circulation, Excretion, Dogs, Internal medicine, Receptors, Adrenergic, beta, Medicine, Animals, Renal circulation, Microvilli, urogenital system, business.industry, Isoproterenol, gamma-Glutamyltransferase, Stimulation, Chemical, Endocrinology, medicine.anatomical_structure, Renal blood flow, Female, business, Lysosomes, medicine.drug, Glomerular Filtration Rate
Abstract

The effects of intrarenal administration of isoproterenol on excretion of urinary enzymes were examined in dogs. Urinary N-acetyl-beta-D-glucosaminidase (NAG) and glutamyl transpeptidase (gamma-GTP) originated from lysosomes and the brush border membrane of the kidney, respectively. NAG excretion was elevated for 10 min by isoproterenol (0.2 microgram/kg/min) without a drastic change in glomerular filtration rate and renal blood flow. This elevation was inhibited by pretreatment with d,l-propranolol (0.6 mg/kg bolus injection 0.3 mg/kg/30 min) but less so by d-propranolol. Urinary gamma-GTP excretion was little affected by isoproterenol. In light of these findings, the possibility that beta-receptors may be involved in the excretion of NAG has to be considered.

Published
1984

5. Subject Index, Vol. 36, 1984

Author

B. Basolo, James R. Oster, W.J.F. van der Vijgh, German Ramirez, Hiroki Tuchida, Jerry L. Newton, Kazuro Kanatsu, J.G. Martinelli, Yoshihiro Hamashima, S. Talarico, M. Aladjem, P. Coruzzi, Arthur H. Cohen, R.H. Albuquerque, David C. Kem, G. Koren, J.S. Pierce, G.P. Segoloni, Hidehiko Kashiwabara, H.A. Koomans, D.J. Leehey, Patoula V. Caralis, M.J.M. Jongen, Guido O. Perez, S. Lamon, A. Vercellone, Frank H. Anderson, G.P. Campos, U. Ruberto, M. D’Amicone, C. Canavese, R.C.J. Ribeiro, T.S. Ing, L.O. Simpson, A.B. Geers, Amin A. Nanji, J.C. Netelenbos, L. Musiari, J.T. Daugirdas, A. Novarini, J.M. Calatrava, M.E. Martínez, Elisa Minelli Bertazzoni, Giovanni Panzetta, H. Boichis, Hideo Shishido, M. Taccone-Gallucci, Naoshi Kohrogi, Toshio Doi, L. Sánchez Agudo, Jugoro Takeuchi, Hiroyuki Nagai, Takashi Kuwahara, A. Montero, P.S.S. Beraldo, Satoshi Akabane, O. Giardini, Shunichiro Sakurai, Harry J. Ward, A. Jonash, Shigeo Tomura, I. Silvi, C.U. Casciani, Minoru Kawamura, J. Militiano, D. Bandino, E.J. Dorhout Mees, A. Borghetti, P. Lips, Wayne A. Border, Koichi Ogino, R. Selgas, F. Escuin, G. Ricciardi-Tenore, G. Piccoli, M.R. Bulzomi, Carl D. Brueggemeyer, R. Coppo, Keiichi Ito, A. da Costa e Suva, E. Rossi, Tetsuya Miyajima, R. Lubrano, Rene Pelleya, P. Gómez-Fernández, Kimiyoshi Tsuji, L. Sánchez-Sicilia, B. Seegal, and F.A.R. Neves

Subjects
Index (economics), business.industry, Statistics, Medicine, Subject (documents), business
Published
1984
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