13 results on '"M. van Buren"'
Search Results
2. Choosing conservative care in advanced chronic kidney disease: a scoping review of patients' perspectives.
- Author
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Jongejan M, de Lange S, Bos WJW, Pieterse AH, Konijn WS, van Buren M, Abrahams AC, and van Oevelen M
- Subjects
- Humans, Renal Dialysis, Quality of Life, Emotions, Decision Making, Kidney Failure, Chronic therapy, Renal Insufficiency, Chronic
- Abstract
Background: Conservative care (CC) is a viable treatment option for some patients with kidney failure. Choosing between dialysis and CC can be a complex decision in which involvement of patients is desirable. Gaining insight into the experiences and preferences of patients regarding this decision-making process is an important initial step to improve care. We aimed to identify what is known about the perspective of patients regarding decision-making when considering CC., Methods: PubMed, EMBASE and Cochrane databases were systematically searched on 23 February 2023 for qualitative and quantitative studies on patient-reported experiences on decision-making about CC. Data were analysed thematically., Results: Twenty articles were included. We identified three major themes: creating awareness about disease and treatment choice, decision support and motivation to choose CC. Patients were often not aware of the option to choose CC. Patients felt supported by their loved ones during the decision-making process, although they perceived they made the final decision to choose CC themselves. Some patients felt pressured by their healthcare professional to choose dialysis. Reported reasons to choose CC were maintaining quality of life, treatment burden of dialysis, cost and the desire not to be a burden to others. In general, patients were satisfied with their decision for CC., Conclusions: By focussing on the perspective of patients, we identified a wide range of patient experiences and preferences regarding the decision-making process. These findings can help to improve the complex decision-making process between dialysis and CC and to provide patient-centred care., (© The Author(s) 2023. Published by Oxford University Press on behalf of the ERA.)
- Published
- 2024
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3. Health-related quality of life and symptom burden in patients on haemodialysis.
- Author
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van Oevelen M, Bonenkamp AA, van Eck van der Sluijs A, Bos WJW, Douma CE, van Buren M, Meuleman Y, Dekker FW, van Jaarsveld BC, and Abrahams AC
- Subjects
- Humans, Aged, Quality of Life, Symptom Burden, Health Surveys, Renal Dialysis, Kidney Failure, Chronic therapy
- Abstract
Background: Patients on haemodialysis (HD) generally experience poor health-related quality of life (HRQoL) and a broad range of physical and mental symptoms, but it is unknown whether this differs between younger and older patients. We aimed to describe the trajectories of HRQoL and symptom burden of patients <70 and ≥70 years old and to assess the impact of symptom burden on HRQoL., Methods: In incident Dutch HD patients, HRQoL and symptoms were measured with the 12-item Short Form Health Survey and Dialysis Symptom Index. We used linear mixed models for examining the trajectories of HRQoL and symptom burden during the first year of dialysis and linear regression for the impact of symptom burden on HRQoL., Results: In 774 patients, the trajectories of physical HRQoL, mental HRQoL and symptom burden were stable during the first year of dialysis. Compared with patients <70 years of age, patients ≥70 years reported similar physical HRQoL {mean difference -0.61 [95% confidence interval (CI) -1.86-0.63]}, better mental HRQoL [1.77 (95% CI 0.54-3.01)] and lower symptom burden [-2.38 (95% CI -5.08-0.32)]. With increasing symptom burden, physical HRQoL declined more in older than in younger patients (β = -0.287 versus -0.189, respectively; P-value for interaction = .007). For mental HRQoL, this decrease was similar in both age groups (β = -0.295 versus -0.288, P = .847)., Conclusion: Older HD patients generally experience a better mental HRQoL and a (non-statistically significant) lower symptom burden compared with younger patients. Their physical HRQoL declines more rapidly with increasing symptom burden., (© The Author(s) 2023. Published by Oxford University Press on behalf of the ERA.)
- Published
- 2024
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4. Survival of patients who opt for dialysis versus conservative care: a systematic review and meta-analysis.
- Author
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Voorend CGN, van Oevelen M, Verberne WR, van den Wittenboer ID, Dekkers OM, Dekker F, Abrahams AC, van Buren M, Mooijaart SP, and Bos WJW
- Subjects
- Cohort Studies, Comorbidity, Glomerular Filtration Rate, Humans, Frailty, Renal Dialysis methods
- Abstract
Background: Non-dialytic conservative care (CC) has been proposed as a treatment option for patients with kidney failure. This systematic review and meta-analysis aims at comparing survival outcomes between dialysis and CC in studies where patients made an explicit treatment choice., Methods: Five databases were systematically searched from origin through 25 February 2021 for studies comparing survival outcomes among patients choosing dialysis versus CC. Adjusted and unadjusted survival rates were extracted and meta-analysis performed where applicable. Risk of bias analysis was performed according to the Cochrane Risk Of Bias In Non-randomized Studies of Interventions., Results: A total of 22 cohort studies were included covering 21 344 patients. Most studies were prone to selection bias and confounding. Patients opting for dialysis were generally younger and had fewer comorbid conditions, fewer functional impairments and less frailty than patients who chose CC. The unadjusted median survival from treatment decision or an estimated glomerular filtration rate <15 mL/min/1.73 m2 ranged from 20 and 67 months for dialysis and 6 and 31 months for CC. Meta-analysis of 12 studies that provided adjusted hazard ratios (HRs) for mortality showed a pooled adjusted HR of 0.47 (95% confidence interval 0.39-0.57) for patients choosing dialysis compared with CC. In subgroups of patients with older age or severe comorbidities, the reduction of mortality risk remained statistically significant, although analyses were unadjusted., Conclusions: Patients opting for dialysis have an overall lower mortality risk compared with patients opting for CC. However, a high risk of bias and heterogeneous reporting preclude definitive conclusions and results cannot be translated to an individual level., Competing Interests: Outside the submitted work, C.G.N.V. has received grant support from the Dutch Kidney Foundation and Nephrosearch Foundation; W.R.V. has received grant support from Zilveren Kruis; W.J.W.B. has received grant support from Zilveren Kruis and the Dutch Kidney Foundation; and M.v.B has received grant support from the Dutch Kidney Foundation and Healthcare Evaluation Leading the Change. The remaining authors declare that they have no conflicts of interest., (© The Author(s) 2022. Published by Oxford University Press on behalf of the ERA.)
- Published
- 2022
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5. Circulating angiopoietin-2 and angiogenic microRNAs associate with cerebral small vessel disease and cognitive decline in older patients reaching end-stage renal disease.
- Author
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Bijkerk R, Kallenberg MH, Zijlstra LE, van den Berg BM, de Bresser J, Hammer S, Bron EE, Achterberg H, van Buchem MA, Berkhout-Byrne NC, Bos WJW, van Heemst D, Rabelink TJ, van Zonneveld AJ, van Buren M, and Mooijaart S
- Subjects
- Aged, Angiopoietin-2 genetics, Cognition, Humans, Magnetic Resonance Imaging methods, Neuropsychological Tests, Cerebral Small Vessel Diseases complications, Cerebral Small Vessel Diseases epidemiology, Cerebral Small Vessel Diseases genetics, Cognitive Dysfunction genetics, Kidney Failure, Chronic complications, Kidney Failure, Chronic genetics, MicroRNAs genetics
- Abstract
Background: The prevalence of end-stage renal disease (ESRD) is increasing worldwide, with the majority of new ESRD cases diagnosed in patients >60 years of age. These older patients are at increased risk for impaired cognitive functioning, potentially through cerebral small vessel disease (SVD). Novel markers of vascular integrity may be of clinical value for identifying patients at high risk for cognitive impairment., Methods: We aimed to associate the levels of angiopoietin-2 (Ang-2), asymmetric dimethylarginine and a selection of eight circulating angiogenic microRNAs (miRNAs) with SVD and cognitive impairment in older patients reaching ESRD that did not yet initiate renal replacement therapy (n = 129; mean age 75.3 years, mean eGFR 16.4 mL/min). We assessed brain magnetic resonance imaging changes of SVD (white matter hyperintensity volume, microbleeds and the presence of lacunes) and measures of cognition in domains of memory, psychomotor speed and executive function in a neuropsychological test battery., Results: Older patients reaching ESRD showed an unfavourable angiogenic profile, as indicated by aberrant levels of Ang-2 and five angiogenic miRNAs (miR-27a, miR-126, miR-132, miR-223 and miR-326), compared with healthy persons and patients with diabetic nephropathy. Moreover, Ang-2 was associated with SVD and with the domains of psychomotor speed and executive function, while miR-223 and miR-29a were associated with memory function., Conclusions: Taken together, these novel angiogenic markers might serve to identify older patients with ESRD at risk of cognitive decline, as well as provide insights into the underlying (vascular) pathophysiology., (© The Author(s) 2020. Published by Oxford University Press on behalf of the ERA.)
- Published
- 2022
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6. Dialysis withdrawal in The Netherlands between 2000 and 2019: time trends, risk factors and centre variation.
- Author
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van Oevelen M, Abrahams AC, Bos WJW, Hoekstra T, Hemmelder MH, Ten Dam M, and van Buren M
- Subjects
- Female, Humans, Netherlands epidemiology, Registries, Risk Factors, Kidney Failure, Chronic therapy, Renal Dialysis
- Abstract
Background: Dialysis withdrawal is a common cause of death in dialysis-dependent patients. This study aims to describe dialysis withdrawal practice in The Netherlands, focussing on time trends, risk factors and centre variation., Methods: Data were retrieved from the Dutch registry of kidney replacement therapy patients. All patients who started maintenance dialysis and died in the period 2000-2019 were included. The main outcome was death after dialysis withdrawal; all other causes of death were used for comparison. Time trends were analysed as unadjusted data (proportion per year) and the year of death was included in a multivariable logistic model. Univariable and multivariable analyses were performed to identify factors associated with withdrawal. Centre variation was compared using funnel plots., Results: A total of 34 692 patients started dialysis and 18 412 patients died while on dialysis. Dialysis withdrawal was an increasingly common cause of death, increasing from 18.3% in 2000-2004 to 26.8% in 2015-2019. Of all patients withdrawing, 26.1% discontinued treatment within their first year. In multivariable analysis, increasing age, female sex, haemodialysis as a treatment modality and year of death were independent factors associated with death after dialysis withdrawal. Centre variation was large (80.7 and 57.4% within 95% control limits of the funnel plots for 2000-2009 and 2010-2019, respectively), even after adjustment for confounding factors., Conclusions: Treatment withdrawal has become the main cause of death among dialysis-dependent patients in The Netherlands, with large variations between centres. These findings emphasize the need for timely advance care planning and improving the shared decision-making process on choosing dialysis or conservative care., (© The Author(s) 2021. Published by Oxford University Press on behalf of ERA-EDTA.)
- Published
- 2021
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7. Changing the choice from dialysis to conservative care or vice versa in older patients with advanced chronic kidney disease.
- Author
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Voorend CGN, Verberne WR, van Oevelen M, Meuleman Y, van Buren M, and Bos WJW
- Subjects
- Aged, Humans, Renal Dialysis, Kidney Failure, Chronic therapy, Renal Insufficiency, Chronic therapy
- Published
- 2021
- Full Text
- View/download PDF
8. Health-related quality of life and symptoms of conservative care versus dialysis in patients with end-stage kidney disease: a systematic review.
- Author
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Verberne WR, van den Wittenboer ID, Voorend CGN, Abrahams AC, van Buren M, Dekker FW, van Jaarsveld BC, van Loon IN, Mooijaart SP, Ocak G, van Delden JJM, and Bos WJW
- Subjects
- Cohort Studies, Humans, Prospective Studies, Renal Dialysis, Kidney Failure, Chronic therapy, Quality of Life
- Abstract
Background: Non-dialytic conservative care (CC) has been proposed as a viable alternative to maintenance dialysis for selected older patients to treat end-stage kidney disease (ESKD). This systematic review compares both treatment pathways on health-related quality of life (HRQoL) and symptoms, which are major outcomes for patients and clinicians when deciding on preferred treatment., Methods: We searched PubMed, Embase, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus and PsycINFO from inception to 1 October 2019 for studies comparing patient-reported HRQoL outcomes or symptoms between patients who chose either CC or dialysis for ESKD., Results: Eleven observational cohort studies were identified comprising 1718 patients overall. There were no randomized controlled trials. Studies were susceptible to selection bias and confounding. In most studies, patients who chose CC were older and had more comorbidities and worse functional status than patients who chose dialysis. Results were broadly consistent across studies, despite considerable clinical and methodological heterogeneity. Patient-reported physical health outcomes and symptoms appeared to be worse in patients who chose CC compared with patients who chose dialysis but had not yet started, but similar compared with patients on dialysis. Mental health outcomes were similar between patients who chose CC or dialysis, including before and after dialysis start. In patients who chose dialysis, the burden of kidney disease and impact on daily life increased after dialysis start., Conclusions: The available data, while heterogeneous, suggest that in selected older patients, CC has the potential to achieve similar HRQoL and symptoms compared with a dialysis pathway. High-quality prospective studies are needed to confirm these provisional findings., (© The Author(s) 2020. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.)
- Published
- 2021
- Full Text
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9. Pre-dialysis decline of measured glomerular filtration rate but not serum creatinine-based estimated glomerular filtration rate is a risk factor for mortality on dialysis.
- Author
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Ramspek CL, Nacak H, van Diepen M, van Buren M, Krediet RT, Rotmans JI, and Dekker FW
- Subjects
- Female, Humans, Kidney Failure, Chronic blood, Kidney Failure, Chronic therapy, Kidney Function Tests, Male, Middle Aged, Prognosis, Prospective Studies, Retrospective Studies, Risk Factors, Creatinine blood, Glomerular Filtration Rate, Kidney Failure, Chronic mortality, Renal Dialysis mortality
- Abstract
Background: Monitoring of renal function is important in patients with chronic kidney disease progressing towards end-stage renal failure, both for timing the start of renal replacement therapy and for determining the prognosis on dialysis. Thus far, studies on associations between estimated glomerular filtration rate (eGFR) measurements in the pre-dialysis stage and mortality on dialysis have shown no or even inverse relations, which may result from the poor validity of serum creatinine-based estimation equations for renal function in pre-dialysis patients. As decline in renal function may be better reflected by the mean of the measured creatinine and urea clearance based on 24-h urine collections (mGFR by C Cr-U ), we hypothesize that in patients with low kidney function, a fast mGFR decline is a risk factor for mortality on dialysis, in contrast to a fast eGFR decline., Methods: For 197 individuals, included from the multicentre NECOSAD cohort, pre-dialysis annual decline of mGFR and eGFR was estimated with linear regression, and classified according to KDOQI as fast (>4 mL/min/1.73 m 2 /year) or slow (≤4 mL/min/1.73 m 2 /year). Cox regression was used to adjust for potential confounders., Results: Patients with a fast mGFR decline had an increased risk of mortality on dialysis: crude hazard ratio (HR) 1.84 (95% confidence interval: 1.13-2.98), adjusted HR 1.94 (1.11-3.36). In contrast, no association was found between a fast eGFR decline in the pre-dialysis phase and mortality on dialysis: crude HR 1.20 (0.75-1.89), adjusted HR 1.14 (0.67-1.94)., Conclusions: This study demonstrates the importance of mGFR decline (by C Cr-U ) as opposed to eGFR decline in patients with low kidney function, and gives incentive for repeated mGFR measurements in patients on pre-dialysis care., (© The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.)
- Published
- 2017
- Full Text
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10. Quality of care in patients with chronic kidney disease is determined by hospital specific factors.
- Author
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van Zuilen AD, Blankestijn PJ, van Buren M, ten Dam MA, Kaasjager KA, Ligtenberg G, Sijpkens YW, Sluiter HE, van de Ven PJ, Vervoort G, Vleming LJ, Bots ML, and Wetzels JF
- Subjects
- Adult, Aged, Cardiovascular Diseases etiology, Chronic Disease, Female, Hospitals, Humans, Kidney Diseases complications, Male, Middle Aged, Randomized Controlled Trials as Topic, Risk Factors, Kidney Diseases therapy, Quality of Health Care
- Abstract
Background: Guidelines have set goals for risk factor management in chronic kidney disease (CKD) patients. These goals are often not met. In this analysis, we set out to assess the quality of risk factor management in CKD and to identify factors that determine the quality of care (QoC). For that purpose, baseline data of the MASTERPLAN (Multifactorial Approach and Superior Treatment Efficacy in Renal Patients with the Aid of Nurse practitioners) study have been used. MASTERPLAN is a multicentre study which evaluates the effect of a multifactorial intervention in prevalent CKD patients on cardiovascular (CV) events and progression of kidney failure., Methods: QoC was quantified using a score based on the number of 11 defined treatment goals on target. The maximum score per patient was 11., Results: The average (±SD) QoC score was 6.7 (±1.5). The average score per centre ranged from 5.9 to 6.9. In a multivariable analysis, centre proved to be a significant, independent determinant of QoC with a difference up to 0.7 between centres. This difference remained when adjustments were made for those risk factors primarily treated by pharmacotherapy. Other factors that were significantly related to the QoC were estimated glomerular filtration rate, Caucasian race, diabetes mellitus, diabetic nephropathy as cause of kidney disease and previous kidney transplantation., Conclusions: In CKD patients, risk factors for progression of kidney failure and CV events were inadequately controlled. Treatment centre proved to be an important determinant of QoC. This data may point towards the physician's interest and preference as important determinants of QoC. This is a potentially modifiable determinant of the quality of patient care [Trial registration ISRCTN registry: 73187232 (http://isrctn.org)].
- Published
- 2010
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11. Patients' representations of their end-stage renal disease: relation with mortality.
- Author
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van Dijk S, Scharloo M, Kaptein AA, Thong MS, Boeschoten EW, Grootendorst DC, Krediet RT, Dekker FW, Apperloo AJ, Bijlsma JA, Boekhout M, Boer WH, van der Boog PJ, Büller HR, van Buren M, de Charro FT, Doorenbos CJ, van den Dorpel MA, van Es A, Fagel WJ, Feith GW, de Fijter CW, Frenken LA, van Geelen JA, Gerlag PG, Grave W, Gorgels JP, Huisman RM, Jager KJ, Jie K, Koning-Mulder WA, Koolen MI, Hovinga TK, Lavrijssen AT, Luik AJ, van der Meulen J, Parlevliet KJ, Raasveld MH, van der Sande FM, Schonck MJ, Schuurmans MM, Siegert CE, Stegeman CA, Stevens P, Thijssen JG, Valentijn RM, Vastenburg GH, Verburgh CA, Vincent HH, and Vos PF
- Subjects
- Aged, Female, Humans, Male, Surveys and Questionnaires, Kidney Failure, Chronic mortality, Kidney Failure, Chronic psychology
- Abstract
Background: Self-regulation theory explains how patients' illness perceptions influence self-management behaviour (e.g. via adherence to treatment). Following these assumptions, we explored whether illness perceptions of ESRD-patients are related to mortality rates., Methods: Illness perceptions of 182 patients participating in the NECOSAD-2 study in the period between December 2004 and June 2005 were assessed. Cox proportional hazard models were used to estimate whether subsequent all-cause mortality could be attributed to illness perception dimensions., Results: One-third of the participants had died at the end of the follow-up. Mortality rates were higher among patients who believed that their treatment was less effective in controlling their disease (perceived treatment control; RR = 0.71, P = 0.028). This effect remained stable after adjusting for sociodemographic and clinical variables (RR = 0.65, P = 0.015)., Conclusions: If we consider risk factors for mortality, we tend to rely on clinical parameters rather than on patients' representations of their illness. Nevertheless, results from the current exploration may suggest that addressing patients' personal beliefs regarding the effectiveness of treatment can provide a powerful tool for predicting and perhaps even enhancing survival.
- Published
- 2009
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12. A stony history.
- Author
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van Buren M
- Subjects
- Diagnosis, Differential, Humans, Hydronephrosis complications, Hydronephrosis therapy, Kidney diagnostic imaging, Lithotripsy, Male, Middle Aged, Nephrocalcinosis complications, Nephrocalcinosis therapy, Renal Dialysis, Renal Insufficiency diagnosis, Renal Insufficiency etiology, Renal Insufficiency therapy, Ultrasonography, Urinary Calculi complications, Urinary Calculi therapy, Urography, Hydronephrosis diagnostic imaging, Hyperoxaluria, Primary diagnosis, Nephrocalcinosis diagnostic imaging, Urinary Calculi diagnostic imaging
- Published
- 2000
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13. Natriuretic and kaliuretic response to potassium load: modulation by sodium intake.
- Author
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van Buren M, Rabelink AJ, Bijlsma JA, and Koomans HA
- Subjects
- Adolescent, Adult, Aldosterone blood, Female, Humans, Male, Natriuresis, Potassium urine, Sodium, Dietary administration & dosage
- Abstract
Potassium (K) loading is followed by a rapid increase in sodium (Na) and K excretion. To evaluate the influence of Na intake on this effect, we studied the acute natriuretic and kaliuretic response to a single oral K load (100 mmol) in six healthy volunteers equilibrated on a 10-, 100-, and 400-mmol Na intake. Compared to the 100-mmol Na intake, the 400-mmol Na intake greatly enhanced the natriuretic effect of the K load; during the 10-mmol Na intake no natriuresis but even some Na retention occurred. The kaliuretic effect was not significantly changed and occurred at similar values of plasma K. Plasma aldosterone was suppressed during the 400-mmol Na diet and stimulated during the 10-mmol Na diet, but the relative increments after the KCl load did not differ among the three diets. In conclusion, whereas the effect of a K load on kaliuresis is relatively independent of Na intake, its effect on Na excretion varies from marked natriuresis to slight Na retention. The Na retention is probably due to acute K-induced aldosterone stimulation, and the natriuresis to K-induced increase in distal Na delivery not utilized to promote K excretion. Apparently, the integration of renal Na and K handling after a K load is such that K balance is maintained at the cost of Na balance.
- Published
- 1993
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