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1. Current structure and organization for renal patient assistance in Italy

Author

Alloatti, S, Strippoli, Gf, Buccianti, G, Daidone, G, Schena, FP Bonomini, M, Iannuzziello, F, Cicchetti, T, Avella, F, Cagnoli, L, Panzetta, O, Simeoni, P, Garibotto, Giacomo, Pedrini, L, Concetti, M, Brigante, M, Triolo, G, Gesualdo, L, Cogoni, G, Marrocco, L, Rindi, P, Rovati, C, Standoli, M, Marchini, P., and Italian Society of Nephrology

Subjects
Nephrology, medicine.medical_specialty, medicine.medical_treatment, Population, urologic and male genital diseases, Ambulatory Care Facilities, Renal Dialysis, Surveys and Questionnaires, Internal medicine, medicine, Humans, Renal replacement therapy, Intensive care medicine, education, Dialysis, Transplantation, education.field_of_study, business.industry, Public health, medicine.disease, Renal Replacement Therapy, Hemodialysis Units, Hospital, Italy, Emergency medicine, Kidney Failure, Chronic, Hemodialysis, Morbidity, business, Delivery of Health Care, Kidney disease
Abstract

Background. Given the public health challenge and burden of chronic kidney disease, the Italian Society ofNephrology (SIN) has compiled a national census of Renal Units (RU) existing in the twenty Italian regions related to the year 2004. Methods. An on-line questionnaire including 158 items explored structural and human resources, organization aspects, activities and epidemiological data in SIN, 2004. Results. The census identified 363 public RU, 303 satellite Dialysis Centres (DC) and 295 private DC totalling 961 DC [16.4 per million population (pmp)]. The inpatient renal beds were 2742 (47 pmp). Renal and dialysis activity was performed by 3728 physicians (64 pmp), of whom 2964 (80%) were nephrologists. There was no permanent medical assistance in 41% of satellite DC. There were 1802 renal admissions pmp and 99 renal biopsies pmp. The management of acute renal failure (13 456 cases; 230 pmp) represented a relevant proportion of the activities conducted in public RU. In 2004 there were 9858 new cases of end-stage kidney disease requiring renal replacement therapy (RRT) (169 pmp). On 31 December 2004, 60 058 patients were on RRT (1027 pmp), 43 293 of which (740 pmp) were on dialysis and 16 765 (287 pmp) with renal graft. Conclusions. This census of the Italian RU and DC in 2004 provides decision makers and healthcare stakeholders with detailed data for benchmarking and has financial implications for the public health system. Similar analyses may be conducted in other countries permitting standardization of medical and cost-related aspects of renal care.

Published
2007
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2. DIALYSIS MINERAL BONE DISEASE

Author

Komaba, H., primary, Taniguchi, M., additional, Yamamoto, S., additional, Nomura, T., additional, Fukagawa, M., additional, Pasch, A., additional, De Francisco, A. L., additional, Covic, A., additional, Marzell, B., additional, Arens, H. J., additional, Passlick-Deetjen, J., additional, Jahnen-Dechent, W., additional, Castellano, A., additional, Ruggiero, P., additional, Pedrini, L. A., additional, Barreto, F., additional, Grassmann, A., additional, Marcelli, D., additional, Canaud, B., additional, Kotanko, P., additional, Silva, V. C., additional, Usvyat, L., additional, Pecoits-Filho, R., additional, Consortium, M., additional, Drueke, T. B., additional, Moe, S. M., additional, Abdalla, S., additional, Parfrey, P. S., additional, and Chertow, G. M., additional

Published
2014
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3. Phosphate levels in patients treated with low-flux haemodialysis, pre-dilution haemofiltration and haemodiafiltration: post hoc analysis of a multicentre, randomized and controlled trial

Author

Locatelli, F., primary, Altieri, P., additional, Andrulli, S., additional, Sau, G., additional, Bolasco, P., additional, Pedrini, L. A., additional, Basile, C., additional, David, S., additional, Gazzanelli, L., additional, Tampieri, G., additional, Isola, E., additional, Marzolla, O., additional, Memoli, B., additional, Ganadu, M., additional, Reina, E., additional, Bertoli, S., additional, Ferrara, R., additional, Casu, D., additional, Logias, F., additional, Tarchini, R., additional, Mattana, G., additional, Passaghe, M., additional, Fundoni, G., additional, Villa, G., additional, Di Iorio, B. R., additional, Pontoriero, G., additional, and Zoccali, C., additional

Published
2014
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4. Extracorporeal techniques and adequacy

Author

Chapdelaine, I., primary, Mostovaya, I. M., additional, Blankestijn, P. J., additional, Bots, M. L., additional, van den Dorpel, M. A., additional, Nube, M. J., additional, ter Wee, P. W., additional, Grooteman, M. P. C., additional, Wang, B., additional, Wang, K., additional, Gayrard, N., additional, Ficheux, A., additional, Duranton, F., additional, Guzman, C., additional, Szwarc, I., additional, Bismuth-Mondolfo, J., additional, Brunet, P., additional, Servel, M. F., additional, Argiles, A., additional, Pedrini, L., additional, Mari, F., additional, Barbieri, C., additional, Cattinelli, I., additional, Bellocchio, F., additional, Amato, C., additional, Leypoldt, J. K., additional, Agar, B. U., additional, Culleton, B. F., additional, Eloot, S., additional, and Vanholder, R., additional

Published
2013
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5. Predictors of haemoglobin levels and resistance to erythropoiesis-stimulating agents in patients treated with low-flux haemodialysis, haemofiltration and haemodiafiltration: results of a multicentre randomized and controlled trial

Author

Locatelli, F., primary, Altieri, P., additional, Andrulli, S., additional, Sau, G., additional, Bolasco, P., additional, Pedrini, L. A., additional, Basile, C., additional, David, S., additional, Feriani, M., additional, Nebiolo, P. E., additional, Ferrara, R., additional, Casu, D., additional, Logias, F., additional, Tarchini, R., additional, Cadinu, F., additional, Passaghe, M., additional, Fundoni, G., additional, Villa, G., additional, Di Iorio, B. R., additional, and Zoccali, C., additional

Published
2012
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6. Hypertension

Author

Shin, S. J., primary, Rhee, M.-Y., additional, Lim, C., additional, Lavoz, C., additional, Rodrigues-Di;ez, R., additional, Rayego-Mateos, S., additional, Benito-Martin, A., additional, Rodrigues-Diez, R., additional, Alique, M., additional, Ortiz, A., additional, Mezzano, S., additional, Ruiz-Ortega, M., additional, Axelsson, J., additional, Rippe, A., additional, Sverrisson, K., additional, Rippe, B., additional, Calo, L., additional, Dal Maso, L., additional, Pagnin, E., additional, Caielli, P., additional, Spanos, G., additional, Kalaitzidis, R., additional, Karasavvidou, D., additional, Pappas, K., additional, Balafa, O., additional, Siamopoulos, K., additional, Fang, T.-C., additional, Lee, T. J. F., additional, Pappas, E., additional, Ermeidi, E., additional, Tatsioni, A., additional, Blazquez-Medela, A., additional, Garcia-Sanchez, O., additional, Quiros, Y., additional, Lopez-Hernandez, F. J., additional, Lopez-Novoa, J. M., additional, Martinez-Salgado, C., additional, Wu, H.-Y., additional, Peng, Y.-S., additional, Hung, K.-Y., additional, Tsai, T.-J., additional, Tu, Y.-K., additional, Chien, K.-L., additional, Larsen, T., additional, Mose, F. H., additional, Hansen, A. B., additional, Pedersen, E. B., additional, Quiroz, Y., additional, Rivero, M., additional, Yaguas, K., additional, Rodriguez-Iturbe, B., additional, Xydakis, D., additional, Sfakianaki, M., additional, Petra, C., additional, Maragaki, E., additional, Antonaki, E., additional, Krasoudaki, E., additional, Kostakis, K., additional, Stylianou, K., additional, Papadogiannakis, A., additional, Sagliker, Y., additional, Paylar, N., additional, Heidland, A., additional, Keck, A., additional, Erek, R., additional, Kolasin, P., additional, S Ozkaynak, P., additional, Sagliker, H. S., additional, Gokcay, I., additional, Ritz, E., additional, Koleganova, N., additional, Gross-Weissmann, M.-L., additional, Piecha, G., additional, Reinecke, N., additional, Marquez Cunha, T., additional, M . S. Higa, E., additional, Pfeferman Heilberg, I., additional, Neder, J. A., additional, Nishiura, J. L., additional, Silva Almeida, W., additional, Schor, N., additional, Tapia, E., additional, Sanchez-Lozada, L. G., additional, Cristobal, M., additional, Soto, V., additional, Garci;a-Arroyo, F., additional, Monroy-Sanchez, F., additional, Madero, M., additional, Johnson, R., additional, Kim, S. M., additional, Yang, S. H., additional, Kim, Y. S., additional, Karanovic, S., additional, Fistrek, M., additional, Kos, J., additional, Pecin, I., additional, Premuzic, V., additional, Abramovic, M., additional, Matijevic, V., additional, Cvoriscec, D., additional, Cvitkovic, A., additional, Knezevic, M., additional, Bitunjac, M., additional, Laganovic, M., additional, Jelakovic, B., additional, Liu, F., additional, Wu, M., additional, Fu, P., additional, Klok Matthesen, S., additional, Guldager Lauridsen, T., additional, Vase, H., additional, Gjorup Holland, P., additional, Nykjaer, K. M., additional, Nielsen, S., additional, Bjerregaard Pedersen, E., additional, Montero, M. J., additional, Vink, E., additional, Willemien, V., additional, Michiel, V., additional, Wilko, S., additional, Evert-Jan, V., additional, Blankestijn, P., additional, Zerbi, S., additional, Pedrini, L. A., additional, Zbroch, E., additional, Malyszko, J., additional, Koc-Zorawska, E., additional, Mysliwiec, M., additional, Quelhas-Santos, J., additional, Serrao, P., additional, Soares-Silva, I., additional, Tang, L., additional, Sampaio-Maia, B., additional, Desir, G., additional, Pestana, M., additional, Elsurer, R., additional, Demir, T., additional, Celik, G., additional, Yavas, M., additional, Yavas, O., additional, Murphy, M., additional, Jacquillet, G., additional, Unwin, R. J., additional, Chichger, H., additional, Shirley, D. G., additional, Caraba, A., additional, Andreea, M., additional, Corina, S., additional, Ioan, R., additional, Nowicki, M., additional, Bobik, M., additional, Pawelec, A., additional, Lacisz, J., additional, Zapala, A., additional, Bryc, K., additional, Esposito, C., additional, Scaramuzzi, M. L., additional, Manini, A., additional, Torreggiani, M., additional, Beneventi, F., additional, Spinillo, A., additional, Grosjean, F., additional, Fasoli, G., additional, Dal Canton, A., additional, Christos, C., additional, Bernhard M.W., S., additional, Martin, N., additional, Jan, K., additional, Claus, M., additional, Leyla, R., additional, Jan, B., additional, Ulrich, K., additional, Hermann, H., additional, Menne, J., additional, Pavicevic, M., additional, Markovic, S., additional, and Igrutinovic, Z., additional

Published
2012
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7. Extracorporeal dialysis: techniques and adequacy

Author

Donadio, C., primary, Kanaki, A., additional, Martin-Gomez, A., additional, Garcia, S., additional, Palacios-Gomez, M., additional, Donadio, C., additional, Calia, D., additional, Colombini, E., additional, DI Francesco, F., additional, Ghimenti, S., additional, Onor, M., additional, Tognotti, D., additional, Fuoco, R., additional, Marka-Castro, E., additional, Torres Zamora, M. I., additional, Giron-Mino, J., additional, Jaime-Solis, M. A., additional, Arteaga, L. M., additional, Romero, H., additional, Akonur, A., additional, Leypoldt, K., additional, Asola, M., additional, Culleton, B., additional, Eloot, S., additional, Glorieux, G., additional, Nathalie, N., additional, Vanholder, R., additional, Perez de Jose, A., additional, Verdalles Guzman, U., additional, Abad Esttebanez, S., additional, Vega Martinez, A., additional, Barraca, D., additional, Yuste, C., additional, Bucalo, L., additional, Rincon, A., additional, Lopez-Gomez, J. M., additional, Bataille, P., additional, Celine, P., additional, Raymond, A., additional, Francois, G., additional, Herve, L., additional, Michel, D., additional, Jean Louis, R., additional, Zhu, F., additional, Kotanko, P., additional, Thijssen, S., additional, Levin, N. W., additional, Papamichail, N., additional, Bougiakli, M., additional, Gouva, C., additional, Antoniou, S., additional, Gianitsi, S., additional, Vlachopanou, A., additional, Chachalos, S., additional, Naka, K., additional, Kaarsavvidou, D., additional, Katopodis, K., additional, Michalis, L., additional, Sasaki, K., additional, Yasuda, K., additional, Yamato, M., additional, Surace, A., additional, Rovatti, P., additional, Steckiph, D., additional, Bandini, R., additional, Severi, S., additional, Dellacasa Bellingegni, A., additional, Santoro, A., additional, Arias, M., additional, Sentis, A., additional, Perez, N., additional, Fontsere, N., additional, Vera, M., additional, Rodriguez, N., additional, Arcal, C., additional, Ortega, N., additional, Uriza, F., additional, Cases, A., additional, Maduell, F., additional, Abbas, S. R., additional, Georgianos, P., additional, Sarafidis, P., additional, Nikolaidis, P., additional, Lasaridis, A., additional, Ahmed, A., additional, Kaoutar, H., additional, Mohammed, B., additional, Zouhir, O., additional, Balter, P., additional, Ginsberg, N., additional, Taylor, P., additional, Sullivan, T., additional, Usvyat, L. A., additional, Zabetakis, P., additional, Moissl, U., additional, Ferrario, M., additional, Garzotto, F., additional, Wabel, P., additional, Cruz, D., additional, Tetta, C., additional, Signorini, M. G., additional, Cerutti, S., additional, Brendolan, A., additional, Ronco, C., additional, Heaf, J., additional, Axelsen, M., additional, Pedersen, R. S., additional, Amine, H., additional, Oualim, Z., additional, Ammirati, A. L., additional, Guimaraes de Souza, N. K., additional, Nemoto Matsui, T., additional, Luiz Vieira, M., additional, Alves de Oliveira, W. A., additional, Fischer, C. H., additional, Dias Carneiro, F., additional, Iizuka, I. J., additional, Aparecida de Souza, M., additional, Mallet, A. C., additional, Cruz Andreoli, M. C., additional, Cardoso Dos Santos, B. F., additional, Rosales, L., additional, Dou, Y., additional, Carter, M., additional, Testa, A., additional, Sottini, L., additional, Giacon, B., additional, Prati, E., additional, Loschiavo, C., additional, Brognoli, M., additional, Marseglia, C., additional, Tommasi, A., additional, Sereni, L., additional, Palladino, G., additional, Bove, S., additional, Bosticardo, G., additional, Schillaci, E., additional, Detoma, P., additional, Bergia, R., additional, Park, J. W., additional, Moon, S. J., additional, Choi, H. Y., additional, Ha, S. K., additional, Park, H.-C., additional, Liao, Y., additional, Zhang, L., additional, Fu, P., additional, Igarashi, H., additional, Suzuki, N., additional, Esashi, S., additional, Masakane, I., additional, Panichi, V., additional, De Ferrari, G., additional, Saffiotti, S., additional, Sidoti, A., additional, Biagioli, M., additional, Bianchi, S., additional, Imperiali, P., additional, Gabrielli, C., additional, Conti, P., additional, Patrone, P., additional, Rombola, G., additional, Falqui, V., additional, Mura, C., additional, Icardi, A., additional, Rosati, A., additional, Santori, F., additional, Mannarino, A., additional, Bertucci, A., additional, Jeong, J., additional, Kim, O. K., additional, Kim, N. H., additional, Bots, M., additional, Den Hoedt, C., additional, Grooteman, M. P., additional, Van der Weerd, N. C., additional, Mazairac, A. H. A., additional, Levesque, R., additional, Ter Wee, P. M., additional, Nube, M. J., additional, Blankestijn, P., additional, Van den Dorpel, M. A., additional, Park, Y., additional, Jeon, J., additional, Tessitore, N., additional, Bedogna, V., additional, Girelli, D., additional, Corazza, L., additional, Jacky, P., additional, Guillaume, Q., additional, Julien, B., additional, Marcinkowski, W., additional, Drozdz, M., additional, Milkowski, A., additional, Rydzynska, T., additional, Prystacki, T., additional, August, R., additional, Benedyk-Lorens, E., additional, Bladek, K., additional, Cina, J., additional, Janiszewska, G., additional, Kaczmarek, A., additional, Lewinska, T., additional, Mendel, M., additional, Paszkot, M., additional, Trafidlo, E., additional, Trzciniecka-Kloczkowska, M., additional, Vasilevsky, A., additional, Konoplev, G., additional, Lopatenko, O., additional, Komashnya, A., additional, Visnevsky, K., additional, Gerasimchuk, R., additional, Neivelt, I., additional, Frorip, A., additional, Vostry, M., additional, Racek, J., additional, Rajdl, D., additional, Eiselt, J., additional, Malanova, L., additional, Pechter, U., additional, Selart, A., additional, Ots-Rosenberg, M., additional, Krieter, D. H., additional, Seidel, S., additional, Merget, K., additional, Lemke, H.-D., additional, Wanner, C., additional, Canaud, B., additional, Rodriguez, A., additional, Morgenroth, A., additional, Von Appen, K., additional, Dragoun, G.-P., additional, Fluck, R., additional, Fouque, D., additional, Lockridge, R., additional, Motomiya, Y., additional, Uji, Y., additional, Hiramatsu, T., additional, Ando, Y., additional, Furuta, M., additional, Kuragano, T., additional, Kida, A., additional, Yahiro, M., additional, Otaki, Y., additional, Hasuike, Y., additional, Nonoguchi, H., additional, Nakanishi, T., additional, Sain, M., additional, Kovacic, V., additional, Ljutic, D., additional, Radic, J., additional, Jelicic, I., additional, Yalin, S. F., additional, Trabulus, S., additional, Yalin, A. S., additional, Altiparmak, M. R., additional, Serdengecti, K., additional, Ohtsuka, A., additional, Fukami, K., additional, Ishikawa, K., additional, Ando, R., additional, Kaida, Y., additional, Adachi, T., additional, Sugi, K., additional, Okuda, S., additional, Nesterova, O. B., additional, Suglobova, E. D., additional, Golubev, R. V., additional, Vasiliev, A. N., additional, Lazeba, V. A., additional, Smirnov, A. V., additional, Arita, K., additional, Kihara, E., additional, Maeda, K., additional, Oda, H., additional, Doi, S., additional, Masaki, T., additional, Hidaka, S., additional, Ishioka, K., additional, Oka, M., additional, Moriya, H., additional, Ohtake, T., additional, Nomura, S., additional, Kobayashi, S., additional, Wagner, S., additional, Gmerek, A., additional, Wagner, J., additional, Wizemann, V., additional, Eftimovska - Otovic, N., additional, Spaseska-Gjurovska, K., additional, Bogdanovska, S., additional, Babalj - Banskolieva, E., additional, Milovanceva, M., additional, Grozdanovski, R., additional, Pisani, A., additional, Riccio, E., additional, Mancini, A., additional, Ambuhl, P., additional, Astrid, S., additional, Ivana, P., additional, Martin, H., additional, Thomas, K., additional, Hans-Rudolf, R., additional, Daniel, A., additional, Denes, K., additional, Marco, M., additional, Wuthrich, R. P., additional, Andreas, S., additional, Andrulli, S., additional, Altieri, P., additional, Sau, G., additional, Bolasco, P., additional, Pedrini, L. A., additional, Basile, C., additional, David, S., additional, Feriani, M., additional, Nebiolo, P. E., additional, Ferrara, R., additional, Casu, D., additional, Logias, F., additional, Tarchini, R., additional, Cadinu, F., additional, Passaghe, M., additional, Fundoni, G., additional, Villa, G., additional, DI Iorio, B. R., additional, Zoccali, C., additional, Locatelli, F., additional, Hamamoto, M., additional, Lee, D.-Y., additional, Kim, B., additional, Moon, K. H., additional, LI, Z., additional, Ahrenholz, P., additional, Winkler, R. E., additional, Waitz, G., additional, Wolf, H., additional, Grundstrom, G., additional, Alquist, M., additional, Holmquist, M., additional, Christensson, A., additional, Bjork, P., additional, Abdgawad, M., additional, Ekholm, L., additional, Segelmark, M., additional, Corsi, C., additional, De Bie, J., additional, Mambelli, E., additional, Mortara, D., additional, Arroyo, D., additional, Panizo, N., additional, Quiroga, B., additional, Reque, J., additional, Melero, R., additional, Rodriguez-Ferrero, M., additional, Rodriguez-Benitez, P., additional, Anaya, F., additional, Luno, J., additional, Ragon, A., additional, James, A., additional, Brunet, P., additional, Ribeiro, S., additional, Faria, M. S., additional, Rocha, S., additional, Rodrigues, S., additional, Catarino, C., additional, Reis, F., additional, Nascimento, H., additional, Fernandes, J., additional, Miranda, V., additional, Quintanilha, A., additional, Belo, L., additional, Costa, E., additional, Santos-Silva, A., additional, Arund, J., additional, Tanner, R., additional, Fridolin, I., additional, Luman, M., additional, Clajus, C., additional, Kielstein, J. T., additional, Haller, H., additional, Libutti, P., additional, Lisi, P., additional, Vernaglione, L., additional, Casucci, F., additional, Losurdo, N., additional, Teutonico, A., additional, Lomonte, C., additional, Krisp, C., additional, Wolters, D. A., additional, Matsuyama, M., additional, Tomo, T., additional, Ishida, K., additional, Matsuyama, K., additional, Nakata, T., additional, Kadota, J., additional, Caiazzo, M., additional, Monari, E., additional, Cuoghi, A., additional, Bellei, E., additional, Bergamini, S., additional, Tomasi, A., additional, Baranger, T., additional, Seniuta, P., additional, Berge, F., additional, Drouillat, V., additional, Frangie, C., additional, Rosier, E., additional, Labonia, W., additional, Lescano, A., additional, Rubio, D., additional, Von der Lippe, N., additional, Jorgensen, J. A., additional, Osthus, T. B., additional, Waldum, B., additional, Os, I., additional, Bossola, M., additional, DI Stasio, E., additional, Antocicco, M., additional, Tazza, L., additional, Griveas, I., additional, Karameris, A., additional, Pasadakis, P., additional, Savica, V., additional, Santoro, D., additional, Saitta, S., additional, Tigano, V., additional, Bellinghieri, G., additional, Gangemi, S., additional, Daniela, R., additional, Checherita, I. A., additional, Ciocalteu, A., additional, Vacaroiu, I. A., additional, Niculae, A., additional, Stefaniak, E., additional, Pietrzak, I., additional, Krupa, D., additional, Garred, L., additional, Mancini, E., additional, Corrazza, L., additional, Atti, M., additional, Afsar, B., additional, Stamopoulos, D., additional, Mpakirtzi, N., additional, Gogola, B., additional, Zeibekis, M., additional, Stivarou, D., additional, Panagiotou, M., additional, Grapsa, E., additional, Vega Vega, O., additional, Barraca Nunez, D., additional, Fernandez-Lucas, M., additional, Gomis, A., additional, Teruel, J. L., additional, Elias, S., additional, Quereda, C., additional, Hignell, L., additional, Humphrey, S., additional, Pacy, N., additional, and Afentakis, N., additional

Published
2012
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13. EBPG guideline on dialysis strategies

Author

Tattersall, J., primary, Martin-Malo, A., additional, Pedrini, L., additional, Basci, A., additional, Canaud, B., additional, Fouque, D., additional, Haage, P., additional, Konner, K., additional, Kooman, J., additional, Pizzarelli, F., additional, Tordoir, J., additional, Vennegoor, M., additional, Wanner, C., additional, ter Wee, P., additional, and Vanholder, R., additional

Published
2007
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14. EBPG Guideline on Nutrition

Author

Fouque, D., primary, Vennegoor, M., additional, Ter Wee, P., additional, Wanner, C., additional, Basci, A., additional, Canaud, B., additional, Haage, P., additional, Konner, K., additional, Kooman, J., additional, Martin-Malo, A., additional, Pedrini, L., additional, Pizzarelli, F., additional, Tattersall, J., additional, Tordoir, J., additional, and Vanholder, R., additional

Published
2007
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15. EBPG on Vascular Access

Author

Tordoir, J., primary, Canaud, B., additional, Haage, P., additional, Konner, K., additional, Basci, A., additional, Fouque, D., additional, Kooman, J., additional, Martin-Malo, A., additional, Pedrini, L., additional, Pizzarelli, F., additional, Tattersall, J., additional, Vennegoor, M., additional, Wanner, C., additional, ter Wee, P., additional, and Vanholder, R., additional

Published
2007
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16. EBPG guideline on haemodynamic instability

Author

Kooman, J., primary, Basci, A., additional, Pizzarelli, F., additional, Canaud, B., additional, Haage, P., additional, Fouque, D., additional, Konner, K., additional, Martin-Malo, A., additional, Pedrini, L., additional, Tattersall, J., additional, Tordoir, J., additional, Vennegoor, M., additional, Wanner, C., additional, ter Wee, P., additional, and Vanholder, R., additional

Published
2007
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18. Reply

Author

Feliciani, A., primary and Pedrini, L. A., additional

Published
2007
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21. Convection versus diffusion in dialysis: an Italian prospective multicentre study

Author

Sau, G., Bolasco, P., Locatelli, F., Altieri, P., Andrulli, S., Basile, C., Filippo, S. Di, Feriani, M., Pedrini, L., Santoro, A., and Zoccali, C.

Abstract

The concept of dialysis adequacy has to be widened to include medium size and large molecule removal in addition to urea kinetics. The HEMO study found a non-significant trend toward a beneficial effect on mortality of high-flux dialysis compared with low-flux dialysis. In that study, the beneficial effect of convection could have been attenuated by the fact that 'internal filtration' in high-flux haemodialysis (HD) is lower than that expected by convection in haemofiltration (HF) or haemodiafiltration (HDF). To explore the putative beneficial effect of convection, this Italian multicentre study was planned, comparing on-line convective treatments (HF and HDF) with standard, low-flux HD. The enrolled patients will be evaluated prospectively on their usual treatment for 2 months (baseline period) and subsequently randomized to continue either with low-flux HD (50%) or to start on-line convective treatment (50%), HF or HDF according to a 1:1 ratio. The primary end point of the study will be cardiovascular stability and blood pressure control. As secondary aims of the study, the impact on symptoms, morbidity and mortality will be assessed. Feasibility and patient compliance during HF and HDF treatments will also be evaluated. The experimental phase of the study, of at least 2 years, is divided into a 3-month adaptation period and a subsequent evaluation period. A recruitment period of 1 year is planned. The study design has adequate power to detect an absolute reduction of 3% hypotensive episodes with the experimental convective treatments compared with standard low-flux HD.

Published
2003

22. Rate dependence of acute PTH release and association between basal plasma calcium and set point of calcium-PTH curve in dialysis patients.

Author

De Cristofaro, V, Colturi, C, Masa, A, Comelli, M, and Pedrini, L A

Abstract

In vivo, the control of calcium-mediated acute PTH release during induced hypo- or hypercalcaemia is linked not only to plasma calcium concentration per se but also to the rate and direction of calcium change. In fact, during induced hypocalcaemia, the predominant mechanism that causes PTH to be released is the reduction of plasma Ca(2+) irrespective of the absolute starting concentration of ionized calcium. This mechanism, which is rate-dependent and even activated in conditions of hypercalcaemia, may be involved in the association, reported in several papers, between the basal Ca(2+) and the set point of the calcium-PTH curve.

Published
2001
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23. Effect of high-flux dialysis on the anaemia of haemodialysis patients.

Author

Locatelli, F, Andrulli, S, Pecchini, F, Pedrini, L, Agliata, S, Lucchi, L, Farina, M, La Milia, V, Grassi, C, Borghi, M, Redaelli, B, Conte, F, Ratto, G, Cabiddu, G, Grossi, C, and Modenese, R

Abstract

Anaemia is one of the major clinical characteristics of patients with chronic renal failure, and has a considerable effect on morbidity and mortality. Adequate dialysis is of paramount importance in correcting anaemia by removing small and medium-sized molecules, which may inhibit erythropoiesis. However, high-molecular-weight inhibitors cleared only by means of highly porous membranes have also been found in uraemic serum and it has been claimed from uncontrolled studies that high-flux dialysis could improve anaemia in haemodialysis patients.

Published
2000
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24. Adequate Sodium Balance and Cardiovascular Stability

Author

Locatelli, F., Ponti, R., Pedrini, L., and Di Filippo, S.

Abstract

To evaluate the sodium balance in haemo-dialysis and haemodiafiltration a computerised model has been developed, which calculates net sodium balance from the infusive, diffusive, and convective sodium fluxes for each minute of treatment, updating the value of plasma water ionised sodium concentration at each step. Using this model and assuming constant body-weight, treatment time, and net ultrafiltration, different haemodialysis and haemodiafiltration treatments, with different dialysate sodium concentrations, sodium infusions, and pre-treatment plasma water sodium concentrations were simulated. The results show that a less negative sodium balance is almost always obtained during haemodiafiltration than in haemodialysis, when using the same dialysate sodium concentrations. Therefore, since sodium is an important factor in cardiovascular stability, it is necessary to match sodium balance with other operational parameters when comparing haemodiafiltration with haemodialysis.

Published
1989
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