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Your search keyword '"Kristiaan, Wouters"' showing total 3 results
Start Over Author "Kristiaan, Wouters" Journal nederlands tijdschrift voor diabetologie
3 results on '"Kristiaan, Wouters"'

1. PS1 - 2. Role of the tumour suppressor CDKN2A/p16INK4a in the development of perivascular adipose tissue

Author

Céline Cudejko, Casper G. Schalkwijk, Sarah Anissa Hannou, Anthony Lucas, Bart Staels, Kadiombo Bantubungi, Emanuel Bouchaert, Anne Tailleux, Réjane Paumelle, Jonathan Vanhoutte, Kristiaan Wouters, and Emanuelle Vallez

Subjects
Pathology, medicine.medical_specialty, Adipose tissue, Genome-wide association study, Type 2 diabetes, Biology, medicine.disease, Phenotype, law.invention, Increased risk, CDKN2A, law, Diabetes mellitus, cardiovascular system, medicine, Suppressor
Abstract

Genome wide association studies have been linked the CDKN2A/B locus to an increased risk for atherosclerosis, type 2 diabetes and aneurysm development. These conditions all are linked to perivascular adipose tissue (pAT) accumulation, which has an inflammatory phenotype.

Published
2013
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2. PS1 - 10. Obesity induces CD11c+ macrophages in murine adipose tissue which are distinctive from, but resemble, dendritic cells

Author

Casper G. Schalkwijk, Katrien H.J. Gaens, Kristiaan Wouters, Erwin Wijnands, Coen D.A. Stehouwer, Jarno J.G. van Wegberg, and Erik A.L. Biessen

Subjects
Follicular dendritic cells, Adipose tissue macrophages, Adipose tissue, CD11c, chemical and pharmacologic phenomena, Dendritic cell, Biology, medicine.disease, Obesity, Insulin resistance, Diabetes mellitus, Immunology, medicine, Cancer research
Abstract

During obesity, inflammatory ‘M1’ macrophages infiltrate adipose tissue (AT). These ‘M1’ AT macrophages (ATMs) express the dendritic cell marker CD11c. Dendritic cells are immune regulators that promote insulin resistance. However, it is unclear whether and how CD11c+ ATMs differ from dendritic cells and if they are activated by obesity.

Published
2013
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3. PS1 - 1. Levels of Advanced Glycation Endproducts in carotid atherosclerotic plaques of individuals with and without diabetes correlate with characteristics of rupture-prone lesions

Author

Gerard Pasterkamp, Judith C. Sluimer, Marion J.J. Gijbels, Michael Brownlee, Casper G. Schalkwijk, Kristiaan Wouters, Mat J.A.P. Daemen, Dominique P.V. de Kleijn, Maya S. P. Huijberts, Erik A.L. Biessen, Jean L.J.M. Scheijen, Nordin M J Hanssen, and Coen D.A. Stehouwer

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Diabetes mellitus, Cardiology, Medicine, Plaque rupture, business, medicine.disease, Stroke, Advanced Glycation Endproducts
Abstract

Heart attack and stroke, major causes of death in diabetes, are caused by plaque rupture, in which metabolic characteristics of the plaque are major determinants.

Published
2012
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