1. Next-generation MRI scanner designed for ultra-high-resolution human brain imaging at 7 Tesla.
- Author
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Feinberg, David, Beckett, Alexander, Vu, An, Stockmann, Jason, Huber, Laurentius, Ma, Samantha, Ahn, Sinyeob, Setsompop, Kawin, Cao, Xiaozhi, Park, Suhyung, Wald, Lawrence, Polimeni, Jonathan, Mareyam, Azma, Gruber, Bernhard, Stirnberg, Rüdiger, Liao, Congyu, Yacoub, Essa, Davids, Mathias, Bell, Paul, Rummert, Elmar, Koehler, Michael, Potthast, Andreas, Gonzalez-Insua, Ignacio, Stocker, Stefan, Gunamony, Shajan, Dietz, Peter, and Liu, Chunlei
- Subjects
Humans ,Brain ,Magnetic Resonance Imaging ,Head ,Neuroimaging ,Signal-To-Noise Ratio - Abstract
To increase granularity in human neuroimaging science, we designed and built a next-generation 7 Tesla magnetic resonance imaging scanner to reach ultra-high resolution by implementing several advances in hardware. To improve spatial encoding and increase the image signal-to-noise ratio, we developed a head-only asymmetric gradient coil (200 mT m-1, 900 T m-1s-1) with an additional third layer of windings. We integrated a 128-channel receiver system with 64- and 96-channel receiver coil arrays to boost signal in the cerebral cortex while reducing g-factor noise to enable higher accelerations. A 16-channel transmit system reduced power deposition and improved image uniformity. The scanner routinely performs functional imaging studies at 0.35-0.45 mm isotropic spatial resolution to reveal cortical layer functional activity, achieves high angular resolution in diffusion imaging and reduces acquisition time for both functional and structural imaging.
- Published
- 2023