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Your search keyword '"Marc O. Warmoes"' showing total 2 results
Start Over Author "Marc O. Warmoes" Journal nature immunology
2 results on '"Marc O. Warmoes"'

1. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

Author

Sivan Cohen, Jeffrey C. Rathmell, Laurence A. Turka, Rigel J. Kishton, Marc O. Warmoes, Jason W. Locasale, Nancie J. MacIver, Valerie A. Gerriets, Amanda G. Nichols, Aguirre A. de Cubas, Marc O. Johnson, Peter J. Siska, and Andrew D. Wells

Subjects
0301 basic medicine, Toll-like receptor, Anabolism, Chemistry, Immunology, FOXP3, Metabolism, Oxidative phosphorylation, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Immunology and Allergy, Glycolysis, Receptor, Gene, 030215 immunology
Abstract

T cells undergo metabolic reprogramming after they are activated. Rathmell and colleagues show that inflammatory Toll-like receptor signals induce glycolysis and impair the suppression of regulatory T cells, but Foxp3 can promote a switch to oxidative phosphorylation and suppression.

Published
2016
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2. Foxp3 and Toll-like receptor signaling balance T

Author

Valerie A, Gerriets, Rigel J, Kishton, Marc O, Johnson, Sivan, Cohen, Peter J, Siska, Amanda G, Nichols, Marc O, Warmoes, Aguirre A, de Cubas, Nancie J, MacIver, Jason W, Locasale, Laurence A, Turka, Andrew D, Wells, and Jeffrey C, Rathmell

Subjects
Glucose Transporter Type 1, TOR Serine-Threonine Kinases, Toll-Like Receptors, Cell Differentiation, Forkhead Transcription Factors, Mice, Transgenic, T-Lymphocytes, Helper-Inducer, Mechanistic Target of Rapamycin Complex 1, T-Lymphocytes, Regulatory, Mice, Inbred C57BL, Mice, Metabolism, Multiprotein Complexes, Immune Tolerance, Animals, Glycolysis, Proto-Oncogene Proteins c-akt, Cells, Cultured, Cell Proliferation, Signal Transduction
Abstract

CD4

Published
2016

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