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Your search keyword '"Li, Yingrui"' showing total 12 results
Start Over Author "Li, Yingrui" Journal nature genetics
12 results on '"Li, Yingrui"'

1. Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease

Author

Zhou, Fusheng, primary, Cao, Hongzhi, additional, Zuo, Xianbo, additional, Zhang, Tao, additional, Zhang, Xiaoguang, additional, Liu, Xiaomin, additional, Xu, Ricong, additional, Chen, Gang, additional, Zhang, Yuanwei, additional, Zheng, Xiaodong, additional, Jin, Xin, additional, Gao, Jinping, additional, Mei, Junpu, additional, Sheng, Yujun, additional, Li, Qibin, additional, Liang, Bo, additional, Shen, Juan, additional, Shen, Changbing, additional, Jiang, Hui, additional, Zhu, Caihong, additional, Fan, Xing, additional, Xu, Fengping, additional, Yue, Min, additional, Yin, Xianyong, additional, Ye, Chen, additional, Zhang, Cuicui, additional, Liu, Xiao, additional, Yu, Liang, additional, Wu, Jinghua, additional, Chen, Mengyun, additional, Zhuang, Xuehan, additional, Tang, Lili, additional, Shao, Haojing, additional, Wu, Longmao, additional, Li, Jian, additional, Xu, Yu, additional, Zhang, Yijie, additional, Zhao, Suli, additional, Wang, Yu, additional, Li, Ge, additional, Xu, Hanshi, additional, Zeng, Lei, additional, Wang, Jianan, additional, Bai, Mingzhou, additional, Chen, Yanling, additional, Chen, Wei, additional, Kang, Tian, additional, Wu, Yanyan, additional, Xu, Xun, additional, Zhu, Zhengwei, additional, Cui, Yong, additional, Wang, Zaixing, additional, Yang, Chunjun, additional, Wang, Peiguang, additional, Xiang, Leihong, additional, Chen, Xiang, additional, Zhang, Anping, additional, Gao, Xinghua, additional, Zhang, Furen, additional, Xu, Jinhua, additional, Zheng, Min, additional, Zheng, Jie, additional, Zhang, Jianzhong, additional, Yu, Xueqing, additional, Li, Yingrui, additional, Yang, Sen, additional, Yang, Huanming, additional, Wang, Jian, additional, Liu, Jianjun, additional, Hammarström, Lennart, additional, Sun, Liangdan, additional, Wang, Jun, additional, and Zhang, Xuejun, additional

Published
2016
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2. A large-scale screen for coding variants predisposing to psoriasis

Author

Tang, Huayang, primary, Jin, Xin, additional, Li, Yang, additional, Jiang, Hui, additional, Tang, Xianfa, additional, Yang, Xu, additional, Cheng, Hui, additional, Qiu, Ying, additional, Chen, Gang, additional, Mei, Junpu, additional, Zhou, Fusheng, additional, Wu, Renhua, additional, Zuo, Xianbo, additional, Zhang, Yong, additional, Zheng, Xiaodong, additional, Cai, Qi, additional, Yin, Xianyong, additional, Quan, Cheng, additional, Shao, Haojing, additional, Cui, Yong, additional, Tian, Fangzhen, additional, Zhao, Xia, additional, Liu, Hong, additional, Xiao, Fengli, additional, Xu, Fengping, additional, Han, Jianwen, additional, Shi, Dongmei, additional, Zhang, Anping, additional, Zhou, Cheng, additional, Li, Qibin, additional, Fan, Xing, additional, Lin, Liya, additional, Tian, Hongqing, additional, Wang, Zaixing, additional, Fu, Huiling, additional, Wang, Fang, additional, Yang, Baoqi, additional, Huang, Shaowei, additional, Liang, Bo, additional, Xie, Xuefeng, additional, Ren, Yunqing, additional, Gu, Qingquan, additional, Wen, Guangdong, additional, Sun, Yulin, additional, Wu, Xueli, additional, Dang, Lin, additional, Xia, Min, additional, Shan, Junjun, additional, Li, Tianhang, additional, Yang, Lin, additional, Zhang, Xiuyun, additional, Li, Yuzhen, additional, He, Chundi, additional, Xu, Aie, additional, Wei, Liping, additional, Zhao, Xiaohang, additional, Gao, Xinghua, additional, Xu, Jinhua, additional, Zhang, Furen, additional, Zhang, Jianzhong, additional, Li, Yingrui, additional, Sun, Liangdan, additional, Liu, Jianjun, additional, Chen, Runsheng, additional, Yang, Sen, additional, Wang, Jun, additional, and Zhang, Xuejun, additional

Published
2013
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3. Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

Author

Guo, Guangwu, primary, Sun, Xiaojuan, additional, Chen, Chao, additional, Wu, Song, additional, Huang, Peide, additional, Li, Zesong, additional, Dean, Michael, additional, Huang, Yi, additional, Jia, Wenlong, additional, Zhou, Quan, additional, Tang, Aifa, additional, Yang, Zuoquan, additional, Li, Xianxin, additional, Song, Pengfei, additional, Zhao, Xiaokun, additional, Ye, Rui, additional, Zhang, Shiqiang, additional, Lin, Zhao, additional, Qi, Mingfu, additional, Wan, Shengqing, additional, Xie, Liangfu, additional, Fan, Fan, additional, Nickerson, Michael L, additional, Zou, Xiangjun, additional, Hu, Xueda, additional, Xing, Li, additional, Lv, Zhaojie, additional, Mei, Hongbin, additional, Gao, Shengjie, additional, Liang, Chaozhao, additional, Gao, Zhibo, additional, Lu, Jingxiao, additional, Yu, Yuan, additional, Liu, Chunxiao, additional, Li, Lin, additional, Fang, Xiaodong, additional, Jiang, Zhimao, additional, Yang, Jie, additional, Li, Cailing, additional, Zhao, Xin, additional, Chen, Jing, additional, Zhang, Fang, additional, Lai, Yongqi, additional, Lin, Zheguang, additional, Zhou, Fangjian, additional, Chen, Hao, additional, Chan, Hsiao Chang, additional, Tsang, Shirley, additional, Theodorescu, Dan, additional, Li, Yingrui, additional, Zhang, Xiuqing, additional, Wang, Jian, additional, Yang, Huanming, additional, Gui, Yaoting, additional, Wang, Jun, additional, and Cai, Zhiming, additional

Published
2013
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4. The duck genome and transcriptome provide insight into an avian influenza virus reservoir species

Author

Huang, Yinhua, primary, Li, Yingrui, additional, Burt, David W, additional, Chen, Hualan, additional, Zhang, Yong, additional, Qian, Wubin, additional, Kim, Heebal, additional, Gan, Shangquan, additional, Zhao, Yiqiang, additional, Li, Jianwen, additional, Yi, Kang, additional, Feng, Huapeng, additional, Zhu, Pengyang, additional, Li, Bo, additional, Liu, Qiuyue, additional, Fairley, Suan, additional, Magor, Katharine E, additional, Du, Zhenlin, additional, Hu, Xiaoxiang, additional, Goodman, Laurie, additional, Tafer, Hakim, additional, Vignal, Alain, additional, Lee, Taeheon, additional, Kim, Kyu-Won, additional, Sheng, Zheya, additional, An, Yang, additional, Searle, Steve, additional, Herrero, Javier, additional, Groenen, Martien A M, additional, Crooijmans, Richard P M A, additional, Faraut, Thomas, additional, Cai, Qingle, additional, Webster, Robert G, additional, Aldridge, Jerry R, additional, Warren, Wesley C, additional, Bartschat, Sebastian, additional, Kehr, Stephanie, additional, Marz, Manja, additional, Stadler, Peter F, additional, Smith, Jacqueline, additional, Kraus, Robert H S, additional, Zhao, Yaofeng, additional, Ren, Liming, additional, Fei, Jing, additional, Morisson, Mireille, additional, Kaiser, Pete, additional, Griffin, Darren K, additional, Rao, Man, additional, Pitel, Frederique, additional, Wang, Jun, additional, and Li, Ning, additional

Published
2013
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5. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

Author

Sung, Wing-Kin, primary, Zheng, Hancheng, additional, Li, Shuyu, additional, Chen, Ronghua, additional, Liu, Xiao, additional, Li, Yingrui, additional, Lee, Nikki P, additional, Lee, Wah H, additional, Ariyaratne, Pramila N, additional, Tennakoon, Chandana, additional, Mulawadi, Fabianus H, additional, Wong, Kwong F, additional, Liu, Angela M, additional, Poon, Ronnie T, additional, Fan, Sheung Tat, additional, Chan, Kwong L, additional, Gong, Zhuolin, additional, Hu, Yujie, additional, Lin, Zhao, additional, Wang, Guan, additional, Zhang, Qinghui, additional, Barber, Thomas D, additional, Chou, Wen-Chi, additional, Aggarwal, Amit, additional, Hao, Ke, additional, Zhou, Wei, additional, Zhang, Chunsheng, additional, Hardwick, James, additional, Buser, Carolyn, additional, Xu, Jiangchun, additional, Kan, Zhengyan, additional, Dai, Hongyue, additional, Mao, Mao, additional, Reinhard, Christoph, additional, Wang, Jun, additional, and Luk, John M, additional

Published
2012
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6. Whole-genome sequence of Schistosoma haematobium

Author

Young, Neil D, primary, Jex, Aaron R, additional, Li, Bo, additional, Liu, Shiping, additional, Yang, Linfeng, additional, Xiong, Zijun, additional, Li, Yingrui, additional, Cantacessi, Cinzia, additional, Hall, Ross S, additional, Xu, Xun, additional, Chen, Fangyuan, additional, Wu, Xuan, additional, Zerlotini, Adhemar, additional, Oliveira, Guilherme, additional, Hofmann, Andreas, additional, Zhang, Guojie, additional, Fang, Xiaodong, additional, Kang, Yi, additional, Campbell, Bronwyn E, additional, Loukas, Alex, additional, Ranganathan, Shoba, additional, Rollinson, David, additional, Rinaldi, Gabriel, additional, Brindley, Paul J, additional, Yang, Huanming, additional, Wang, Jun, additional, Wang, Jian, additional, and Gasser, Robin B, additional

Published
2012
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7. Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

Author

Guo, Guangwu, primary, Gui, Yaoting, additional, Gao, Shengjie, additional, Tang, Aifa, additional, Hu, Xueda, additional, Huang, Yi, additional, Jia, Wenlong, additional, Li, Zesong, additional, He, Minghui, additional, Sun, Liang, additional, Song, Pengfei, additional, Sun, Xiaojuan, additional, Zhao, Xiaokun, additional, Yang, Sangming, additional, Liang, Chaozhao, additional, Wan, Shengqing, additional, Zhou, Fangjian, additional, Chen, Chao, additional, Zhu, Jialou, additional, Li, Xianxin, additional, Jian, Minghan, additional, Zhou, Liang, additional, Ye, Rui, additional, Huang, Peide, additional, Chen, Jing, additional, Jiang, Tao, additional, Liu, Xiao, additional, Wang, Yong, additional, Zou, Jing, additional, Jiang, Zhimao, additional, Wu, Renhua, additional, Wu, Song, additional, Fan, Fan, additional, Zhang, Zhongfu, additional, Liu, Lin, additional, Yang, Ruilin, additional, Liu, Xingwang, additional, Wu, Haibo, additional, Yin, Weihua, additional, Zhao, Xia, additional, Liu, Yuchen, additional, Peng, Huanhuan, additional, Jiang, Binghua, additional, Feng, Qingxin, additional, Li, Cailing, additional, Xie, Jun, additional, Lu, Jingxiao, additional, Kristiansen, Karsten, additional, Li, Yingrui, additional, Zhang, Xiuqing, additional, Li, Songgang, additional, Wang, Jian, additional, Yang, Huanming, additional, Cai, Zhiming, additional, and Wang, Jun, additional

Published
2011
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8. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

Author

Gui, Yaoting, primary, Guo, Guangwu, additional, Huang, Yi, additional, Hu, Xueda, additional, Tang, Aifa, additional, Gao, Shengjie, additional, Wu, Renhua, additional, Chen, Chao, additional, Li, Xianxin, additional, Zhou, Liang, additional, He, Minghui, additional, Li, Zesong, additional, Sun, Xiaojuan, additional, Jia, Wenlong, additional, Chen, Jinnong, additional, Yang, Shangming, additional, Zhou, Fangjian, additional, Zhao, Xiaokun, additional, Wan, Shengqing, additional, Ye, Rui, additional, Liang, Chaozhao, additional, Liu, Zhisheng, additional, Huang, Peide, additional, Liu, Chunxiao, additional, Jiang, Hui, additional, Wang, Yong, additional, Zheng, Hancheng, additional, Sun, Liang, additional, Liu, Xingwang, additional, Jiang, Zhimao, additional, Feng, Dafei, additional, Chen, Jing, additional, Wu, Song, additional, Zou, Jing, additional, Zhang, Zhongfu, additional, Yang, Ruilin, additional, Zhao, Jun, additional, Xu, Congjie, additional, Yin, Weihua, additional, Guan, Zhichen, additional, Ye, Jiongxian, additional, Zhang, Hong, additional, Li, Jingxiang, additional, Kristiansen, Karsten, additional, Nickerson, Michael L, additional, Theodorescu, Dan, additional, Li, Yingrui, additional, Zhang, Xiuqing, additional, Li, Songgang, additional, Wang, Jian, additional, Yang, Huanming, additional, Wang, Jun, additional, and Cai, Zhiming, additional

Published
2011
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9. Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Author

Li, Yingrui, primary, Vinckenbosch, Nicolas, additional, Tian, Geng, additional, Huerta-Sanchez, Emilia, additional, Jiang, Tao, additional, Jiang, Hui, additional, Albrechtsen, Anders, additional, Andersen, Gitte, additional, Cao, Hongzhi, additional, Korneliussen, Thorfinn, additional, Grarup, Niels, additional, Guo, Yiran, additional, Hellman, Ines, additional, Jin, Xin, additional, Li, Qibin, additional, Liu, Jiangtao, additional, Liu, Xiao, additional, Sparsø, Thomas, additional, Tang, Meifang, additional, Wu, Honglong, additional, Wu, Renhua, additional, Yu, Chang, additional, Zheng, Hancheng, additional, Astrup, Arne, additional, Bolund, Lars, additional, Holmkvist, Johan, additional, Jørgensen, Torben, additional, Kristiansen, Karsten, additional, Schmitz, Ole, additional, Schwartz, Thue W, additional, Zhang, Xiuqing, additional, Li, Ruiqiang, additional, Yang, Huanming, additional, Wang, Jian, additional, Hansen, Torben, additional, Pedersen, Oluf, additional, Nielsen, Rasmus, additional, and Wang, Jun, additional

Published
2010
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10. A large-scale screen for coding variants predisposing to psoriasis.

Author

Tang H, Jin X, Li Y, Jiang H, Tang X, Yang X, Cheng H, Qiu Y, Chen G, Mei J, Zhou F, Wu R, Zuo X, Zhang Y, Zheng X, Cai Q, Yin X, Quan C, Shao H, Cui Y, Tian F, Zhao X, Liu H, Xiao F, Xu F, Han J, Shi D, Zhang A, Zhou C, Li Q, Fan X, Lin L, Tian H, Wang Z, Fu H, Wang F, Yang B, Huang S, Liang B, Xie X, Ren Y, Gu Q, Wen G, Sun Y, Wu X, Dang L, Xia M, Shan J, Li T, Yang L, Zhang X, Li Y, He C, Xu A, Wei L, Zhao X, Gao X, Xu J, Zhang F, Zhang J, Li Y, Sun L, Liu J, Chen R, Yang S, Wang J, and Zhang X

Subjects
Adult, Aminopeptidases genetics, Asian People genetics, CARD Signaling Adaptor Proteins genetics, Case-Control Studies, Connexin 26, Connexins genetics, Female, Fucosyltransferases genetics, Genome-Wide Association Study, Guanylate Cyclase genetics, Haplotypes, Humans, Male, Membrane Proteins genetics, Minor Histocompatibility Antigens, Mutation, Missense, Nuclear Proteins genetics, RNA-Binding Proteins genetics, Receptors, Interleukin genetics, Young Adult, Galactoside 2-alpha-L-fucosyltransferase, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide, Psoriasis genetics
Abstract

To explore the contribution of functional coding variants to psoriasis, we analyzed nonsynonymous single-nucleotide variants (SNVs) across the genome by exome sequencing in 781 psoriasis cases and 676 controls and through follow-up validation in 1,326 candidate genes by targeted sequencing in 9,946 psoriasis cases and 9,906 controls from the Chinese population. We discovered two independent missense SNVs in IL23R and GJB2 of low frequency and five common missense SNVs in LCE3D, ERAP1, CARD14 and ZNF816A associated with psoriasis at genome-wide significance. Rare missense SNVs in FUT2 and TARBP1 were also observed with suggestive evidence of association. Single-variant and gene-based association analyses of nonsynonymous SNVs did not identify newly associated genes for psoriasis in the regions subjected to targeted resequencing. This suggests that coding variants in the 1,326 targeted genes contribute only a limited fraction of the overall genetic risk for psoriasis.

Published
2014
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11. The genome of the mesopolyploid crop species Brassica rapa.

Author

Wang X, Wang H, Wang J, Sun R, Wu J, Liu S, Bai Y, Mun JH, Bancroft I, Cheng F, Huang S, Li X, Hua W, Wang J, Wang X, Freeling M, Pires JC, Paterson AH, Chalhoub B, Wang B, Hayward A, Sharpe AG, Park BS, Weisshaar B, Liu B, Li B, Liu B, Tong C, Song C, Duran C, Peng C, Geng C, Koh C, Lin C, Edwards D, Mu D, Shen D, Soumpourou E, Li F, Fraser F, Conant G, Lassalle G, King GJ, Bonnema G, Tang H, Wang H, Belcram H, Zhou H, Hirakawa H, Abe H, Guo H, Wang H, Jin H, Parkin IA, Batley J, Kim JS, Just J, Li J, Xu J, Deng J, Kim JA, Li J, Yu J, Meng J, Wang J, Min J, Poulain J, Wang J, Hatakeyama K, Wu K, Wang L, Fang L, Trick M, Links MG, Zhao M, Jin M, Ramchiary N, Drou N, Berkman PJ, Cai Q, Huang Q, Li R, Tabata S, Cheng S, Zhang S, Zhang S, Huang S, Sato S, Sun S, Kwon SJ, Choi SR, Lee TH, Fan W, Zhao X, Tan X, Xu X, Wang Y, Qiu Y, Yin Y, Li Y, Du Y, Liao Y, Lim Y, Narusaka Y, Wang Y, Wang Z, Li Z, Wang Z, Xiong Z, and Zhang Z

Subjects
Arabidopsis genetics, Chromosomes, Artificial, Bacterial genetics, Chromosomes, Plant genetics, Contig Mapping, Evolution, Molecular, Gene Duplication, Genes, Plant, Molecular Sequence Annotation, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA, Brassica rapa genetics, Genome, Plant, Polyploidy
Abstract

We report the annotation and analysis of the draft genome sequence of Brassica rapa accession Chiifu-401-42, a Chinese cabbage. We modeled 41,174 protein coding genes in the B. rapa genome, which has undergone genome triplication. We used Arabidopsis thaliana as an outgroup for investigating the consequences of genome triplication, such as structural and functional evolution. The extent of gene loss (fractionation) among triplicated genome segments varies, with one of the three copies consistently retaining a disproportionately large fraction of the genes expected to have been present in its ancestor. Variation in the number of members of gene families present in the genome may contribute to the remarkable morphological plasticity of Brassica species. The B. rapa genome sequence provides an important resource for studying the evolution of polyploid genomes and underpins the genetic improvement of Brassica oil and vegetable crops.

Published
2011
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12. The genome of the cucumber, Cucumis sativus L.

Author

Huang S, Li R, Zhang Z, Li L, Gu X, Fan W, Lucas WJ, Wang X, Xie B, Ni P, Ren Y, Zhu H, Li J, Lin K, Jin W, Fei Z, Li G, Staub J, Kilian A, van der Vossen EA, Wu Y, Guo J, He J, Jia Z, Ren Y, Tian G, Lu Y, Ruan J, Qian W, Wang M, Huang Q, Li B, Xuan Z, Cao J, Asan, Wu Z, Zhang J, Cai Q, Bai Y, Zhao B, Han Y, Li Y, Li X, Wang S, Shi Q, Liu S, Cho WK, Kim JY, Xu Y, Heller-Uszynska K, Miao H, Cheng Z, Zhang S, Wu J, Yang Y, Kang H, Li M, Liang H, Ren X, Shi Z, Wen M, Jian M, Yang H, Zhang G, Yang Z, Chen R, Liu S, Li J, Ma L, Liu H, Zhou Y, Zhao J, Fang X, Li G, Fang L, Li Y, Liu D, Zheng H, Zhang Y, Qin N, Li Z, Yang G, Yang S, Bolund L, Kristiansen K, Zheng H, Li S, Zhang X, Yang H, Wang J, Sun R, Zhang B, Jiang S, Wang J, Du Y, and Li S

Subjects
DNA Transposable Elements genetics, DNA, Plant chemistry, Gene Duplication, Genes, Plant, Immunity, Innate genetics, Molecular Sequence Data, Plant Diseases genetics, Repetitive Sequences, Nucleic Acid, Synteny, Cucumis sativus genetics, Genome, Plant
Abstract

Cucumber is an economically important crop as well as a model system for sex determination studies and plant vascular biology. Here we report the draft genome sequence of Cucumis sativus var. sativus L., assembled using a novel combination of traditional Sanger and next-generation Illumina GA sequencing technologies to obtain 72.2-fold genome coverage. The absence of recent whole-genome duplication, along with the presence of few tandem duplications, explains the small number of genes in the cucumber. Our study establishes that five of the cucumber's seven chromosomes arose from fusions of ten ancestral chromosomes after divergence from Cucumis melo. The sequenced cucumber genome affords insight into traits such as its sex expression, disease resistance, biosynthesis of cucurbitacin and 'fresh green' odor. We also identify 686 gene clusters related to phloem function. The cucumber genome provides a valuable resource for developing elite cultivars and for studying the evolution and function of the plant vascular system.

Published
2009
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