1. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
- Author
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Zillikens, M.C. (Carola), Stolk, L. (Lisette), Broer, L. (Linda), Amin, N. (Najaf), Campos Obanda, N. (Natalia), Enneman, A.W. (Anke), Estrada Gil, K. (Karol), Hofman, A. (Albert), Kloth, J.S.L. (Jacqueline), Launer, L.J. (Lenore), Medina-Gomez, M.C. (Carolina), Oostra, B.A. (Ben), Zhou, Y. (Yanhua), Duijn, C.M. (Cornelia) van, Rivadeneira Ramirez, F. (Fernando), Uitterlinden, A.G. (André), Kiel, D.P. (Douglas P.), Zillikens, M.C. (Carola), Stolk, L. (Lisette), Broer, L. (Linda), Amin, N. (Najaf), Campos Obanda, N. (Natalia), Enneman, A.W. (Anke), Estrada Gil, K. (Karol), Hofman, A. (Albert), Kloth, J.S.L. (Jacqueline), Launer, L.J. (Lenore), Medina-Gomez, M.C. (Carolina), Oostra, B.A. (Ben), Zhou, Y. (Yanhua), Duijn, C.M. (Cornelia) van, Rivadeneira Ramirez, F. (Fernando), Uitterlinden, A.G. (André), and Kiel, D.P. (Douglas P.)
- Abstract
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body and appendicular lean body mass measured using dual energy X-ray absorptiometry or bioelectrical impedance analysis, adjusted for sex, age, height, and fat mass. Twenty-one single-nucleotide polymorphisms were significantl
- Published
- 2017
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