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Start Over Author "Volker Scheuss" Journal nature communications
1 results on '"Volker Scheuss"'

1. Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

Author

Karl E. Bauer, Inmaculada Segura, Imre Gaspar, Volker Scheuss, Christin Illig, Georg Ammer, Saskia Hutten, Eugénia Basyuk, Sandra M. Fernández-Moya, Janina Ehses, Edouard Bertrand, and Michael A. Kiebler

Subjects
Science
Abstract

Asymmetric subcellular mRNA distribution is important for local translation of neuronal mRNAs. Here the authors employed MS2 live-cell imaging and showed that the reporter mRNA containing the 3’ UTR of Rgs4 shows an anterograde transport bias, dependent on neuronal activity and the protein Staufen2, and mediates sustained mRNA recruitment to synapses.

Published
2019
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