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Your search keyword '"Nichola Cooper"' showing total 2 results
Start Over Author "Nichola Cooper" Journal nature communications
2 results on '"Nichola Cooper"'

1. Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19

Author

Allison K. Maher, Katie L. Burnham, Emma M. Jones, Michelle M. H. Tan, Rocel C. Saputil, Laury Baillon, Claudia Selck, Nicolas Giang, Rafael Argüello, Clio Pillay, Emma Thorley, Charlotte-Eve Short, Rachael Quinlan, Wendy S. Barclay, Nichola Cooper, Graham P. Taylor, Emma E. Davenport, and Margarita Dominguez-Villar

Subjects
Science
Abstract

Although myeloid cell dysfunction has been observed in COVID-19, the underlying mechanisms remain incompletely understood. Here, the authors demonstrate that monocytes from patients with mild to moderate COVID-19 show a blunted innate immune response and a pro-thrombotic signature following secondary SARS-CoV-2 challenge.

Published
2022
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2. Third primary SARS-CoV-2 mRNA vaccines enhance antibody responses in most patients with haematological malignancies

Author

Lucy B. Cook, Gillian O’Dell, Eleni Vourvou, Renuka Palanicawandar, Sasha Marks, Dragana Milojkovic, Jane F. Apperley, Sandra Loaiza, Simone Claudiani, Marco Bua, Catherine Hockings, Donald Macdonald, Aris Chaidos, Jiri Pavlu, Nichola Cooper, Sarah Fidler, Paul Randell, and Andrew J. Innes

Subjects
Science
Abstract

SARS-CoV-2 vaccination has shown reduced efficacy in patients with haematological malignancies. Here, the authors show that a third vaccine is able to enhance SARS-CoV-2 antibody responses in most cases in a cohort of 381 patients with haematological malignancies.

Published
2022
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