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Start Over Author "Michael C. Salling" Journal nature communications
1 results on '"Michael C. Salling"'

1. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications

Author

Kumi Morikawa, Kazuhiro Furuhashi, Carmen de Sena-Tomas, Alvaro L. Garcia-Garcia, Ramsey Bekdash, Alison D. Klein, Nicholas Gallerani, Hannah E. Yamamoto, Seon-Hye E. Park, Grant S. Collins, Fuun Kawano, Moritoshi Sato, Chyuan-Sheng Lin, Kimara L. Targoff, Edmund Au, Michael C. Salling, and Masayuki Yazawa

Subjects
Science
Abstract

Previous versions of photoactivatable Cre recombinase (PA-Cre) suffered from unintentional recombination in dark conditions. Here, the authors develop an improved version of PA-Cre, called PA-Cre 3.0, which shows reduced leakiness and improved efficiency upon activation, and make mouse lines that express PA-Cre 3.0 conditionally.

Published
2020
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