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Start Over Author "Lianqi Huang" Journal nature communications
1 results on '"Lianqi Huang"'

1. ANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ

Author

Yu Zhang, Xian Guo, Wanyao Yan, Yan Chen, Mengxiang Ke, Cheng Cheng, Xiuqin Zhu, Weili Xue, Qiaoqiao Zhou, Ling Zheng, Shun Wang, Bin Wu, Xinran Liu, Liang Ma, Lianqi Huang, and Kun Huang

Subjects
Science
Abstract

NF-κB activation mediated by TNFα has a critical role in inflammation; however, the underlying mechanisms await further investigation. Here the authors show that selective autophagy regulates NF-κB activation via an ANGPTL8/p62-IKKγ signaling axis.

Published
2017
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