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Your search keyword '"Gwenaël Labouèbe"' showing total 1 results
Start Over Author "Gwenaël Labouèbe" Journal nature communications
1 results on '"Gwenaël Labouèbe"'

1. Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion

Author

Anastasiya Strembitska, Gwenaël Labouèbe, Alexandre Picard, Xavier P. Berney, David Tarussio, Maxime Jan, and Bernard Thorens

Subjects
Science
Abstract

During hypoglycemia, glucagon secretion is part of the mechanism needed to restore normal blood glucose levels. Here, Strembitska et al. report that sensing of hypoglycemia by AgRP neurons requires Agpat5, an enzyme which prevents fatty acids from entering the mitochondria for ATP production, ensuring correct neuronal activation and glucagon secretion.

Published
2022
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