1. Laser surgery for mouse geneticists.
- Author
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Gridley, Thomas and Woychik, Rick
- Subjects
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LASER surgery , *GENETICISTS , *LABORATORY mice , *PHENOTYPES , *EMBRYONIC stem cell research , *MICROINJECTIONS , *ANIMAL mutation breeding - Abstract
The authors focus on the laser surgery on mice which are subjected to genetic testing. In order to accelerate phenotype analysis, mutant mice from embryonic stem cells are being generated. The eight cell microinjection procedure in two approaches is being suggested for production of homozygotes. The authors conclude that the need for cost effectiveness for breeding, phenotyping and maintaining the mice will be met by laser surgery.
- Published
- 2007
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