Search

Your search keyword '"Pan, Z.Z."' showing total 1 results
Start Over Author "Pan, Z.Z." Journal nature
1 results on '"Pan, Z.Z."'

1. Cellular mechanism for anti-analgesic action of agonists of the kappa-opioid receptor

Author

Pan, Z.Z., Tershner, S.A., and Fields, H.L.

Subjects
Opioids -- Receptors, Neurology -- Research, Endorphins -- Receptors, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The analgesic effect of opioids primarily activates the mu-opioid receptor but has a similar effect on the kappa-receptor, whose role is less clear. While kappa-receptors produce analgesia, they are also found to antagonize morphine analgesia. New research shows that the activation of the kappa-receptor specifically antagonizes analgesia induced by the mu-receptor. The finding suggest new approaches to the treatment of opioid addiction and pain control.

Published
1997

Catalog

Books, media, physical & digital resources
See catalog results