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1. Resolutions to enhance confident creativity

2. 'Japan's scientists must learn to take action'

3. news in brief

4. Millennial highlights

5. Making waves in physics

6. Astronomy: Optics adapt to the whole sky

7. 100 and 50 years ago

8. Earth science: Taking the temperature of slabs

9. Medical physics: Explaining the T-wave shape in the ECG

10. Forecasting Andean rainfall and crop yield from the influence of El Nino on Pleiades visibility

11. Dynamic biogeography and conservation of endangered species

12. Private vs public genomics?

13. UK discussed ban on foreign job ads in 1960s

14. Brussels research chief backs European website proposal

15. The truth is in here

16. A reduced estimate of the number of kilometre-sized near-Earth asteroids

17. Quick-fire genes, pipettes, RNA

18. Australian university chiefs attack plans for research funding

20. Seeking the great transition

21. The Osler magic revisited

22. Seeing the world in a mote of dust

23. 100 and 50 years ago

24. Atmospheric chemistry: Better budgets for methyl halides?

25. Obituary: Robert A. Swanson (1947-99)

26. Annual fluxes of carbon from deforestation and regrowth in the Brazilian Amazon

27. Regulation of carbamoyl phosphate synthetase by MAP kinase

28. Can biological phenomena be understood by humans?

29. All parties keen to press on with Europe-based science website

30. news in brief

31. Science moves to centre stage

32. Instincts for the past tense

33. Palaeoclimatology: Out of Africa

34. Citation analysis: Democracy on the rocks

35. Global change: Rice, microbes and methane

36. 100 and 50 years ago

37. Earth science: Volcanic action at Axial Seamount

38. Exploring the territory in tissue engineering

39. Electronic submissions now welcome

40. German science begins to cure its historical amnesia

41. Apathy rewards misconduct -- and everybody suffers

42. End of impact factors?

43. Nucleic acids revelation delayed by a sceptic

44. The decade of the sheep

45. 100 and 50 years ago

46. Plant ecology: Alien invaders

47. Correction

48. Quality of the fossil record through time

49. erratum The neurobiology of cognition

50. Scientists reject blame for German genome shortfall