1. Two new 7, 20-epoxy-ent-kauranes from the aerial parts of Isodon eriocalyx
- Author
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Chao-Jun Wang, Zhi-Qi Yin, Zheng-Yun Rao, Li-Hua Zhu, Jian Zhang, Min Jiang, and Shu-Ying Li
- Subjects
010405 organic chemistry ,Chemistry ,Stereochemistry ,Organic Chemistry ,Interleukin ,Plant Science ,Isodon eriocalyx ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Analytical Chemistry ,Interleukin 1β ,010404 medicinal & biomolecular chemistry ,Monosodium urate ,otorhinolaryngologic diseases ,Ent kaurane - Abstract
Two previously undescribed 7, 20-epoxy-ent-kauranes along with six known ent-kauranoids, were isolated from the aerial parts of Isodon eriocalyx. The structures of new compounds were established on the basis of extensive spectroscopic analyses. Compound 2 could inhibit the production of interleukin - 1β (IL - 1β) in monosodium urate (MSU) and lipopolysaccharide (LPS) induced macrophages.
- Published
- 2020
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