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3 results on '"Ilhami, Celik"'

1. A new polyketide from the bark of

Author

François, Damen, Olive Monique F, Demgne, Gabin Thierry M, Bitchagno, Ilhami, Celik, James D Simo, Mpetga, Simplice Beaudelaire, Tankeo, Till, Opatz, Victor, Kuete, and Pierre, Tane

Subjects
Magnetic Resonance Spectroscopy, Drug Resistance, Multiple, Bacterial, Polyketides, Plant Bark, Microbial Sensitivity Tests, Hypericum, Anti-Bacterial Agents
Abstract

The isolation and spectroscopic data of a hitherto undescribed polyketide (

Published
2019

2. Guttiferone BL with antibacterial activity from the fruits of

Author

Blaise Kemajou, Nganou, Ingrid, Simo Konga, Aimé G, Fankam, Gabin Thierry M, Bitchagno, Gaielle, Sonfack, Paul, Nayim, Ilhami, Celik, Sema, Koyutürk, Victor, Kuete, and Pierre, Tane

Subjects
Molecular Structure, Plant Extracts, Methanol, Drug Evaluation, Preclinical, Microbial Sensitivity Tests, Gram-Positive Bacteria, Anti-Bacterial Agents, Benzophenones, Clusiaceae, Fruit, Gram-Negative Bacteria, Escherichia coli, Biflavonoids, Kaempferols
Published
2018

3. Guttiferone BL with antibacterial activity from the fruits of Allanblackia gabonensis.

Author

Nganou, Blaise Kemajou, Simo Konga, Ingrid, Fankam, Aimé G., Bitchagno, Gabin Thierry M., Sonfack, Gaielle, Nayim, Paul, Celik, Ilhami, Koyutürk, Sema, Kuete, Victor, and Tane, Pierre

Subjects
FRUIT, BIOACTIVE compounds, FRUIT extracts, SPECTROMETRY, METHANOL
Abstract

Allanblackia genus, an endless source of bioactive compounds, was investigated for its antibacterial properties. The chemical study of the methanol extract from the fruits of Allanblackia gabonensis resulted in the isolation of the undescribed guttiferone BL (1) along with the known kaempferol (2), morelloflavone (3), morelloflavone 7″-O-β-D-glucopyranoside (4), β-sitosterol 3-O-β-D-glucopyranoside and β-sitosterol. Their structures were determined using spectrometry and spectroscopic techniques. The antibacterial activity was evaluated against five Gram-negative and two Gram-positive strains using a broth micro-dilution method. Compounds displayed low to significant activity against the tested bacterial strains with MICs ranging from 8 to 512 μg/mL. Morelloflavone (3) presented significant activity against E. coli ATCC8739 (MIC = 8 μg/mL) while guttiferone BL (1) exhibited low activity (MICs = 256–512 μg/mL) against all the tested strains. The crude extract also had moderate to significant activity against the tested bacterial strains. [ABSTRACT FROM AUTHOR]

Published
2019
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