1. Bioactive constituents from Michelia champaca
- Author
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Yu-Ting, Yeh, Jin-Cherng, Huang, Po-Lin, Kuo, and Chung-Yi, Chen
- Subjects
Lung Neoplasms ,Plant Stems ,Cell Line, Tumor ,Humans ,Breast Neoplasms ,Female ,Antineoplastic Agents, Phytogenic ,Magnoliaceae - Abstract
(-)-Anonaine (1), (-)-asimilobine (2), (-)-nuciferine (3), (-)-anolobine (4), (-)-romerine (5), (-)-N-acetylanonaine (6), liriodenine (7), (+)-syringaresinol (8), N-trans-feruloyltyramine (9), N-cis-feruloyltyramine (10), scopoletin (11), 4-acetonyl-3,5-dimethoxy-p-quinol (12), vanillin (13), vanillic acid (14), syringic acid (15), beta-sitosterol (16) and stigmasterol (17) were isolated from branches of Michelia champaca L. In addition, a cell proliferation assay of five of the isolated compounds on human breast and lung cancer cells showed that liriodenine (7) was the strongest inhibitor.
- Published
- 2011