Search

Your search keyword '"Schizophyllum drug effects"' showing total 4 results
Start Over Descriptor "Schizophyllum drug effects" Journal mycoses
4 results on '"Schizophyllum drug effects"'

1. Epidural abscess caused by Schizophyllum commune: A rare case of rhinogenic cranial complication by a filamentous basidiomycete.

Author

Tone K, Fujisaki R, Hagiwara S, Tamura T, Ishigaki S, Alshahni MM, Takehisa M, Watanabe T, Yasui T, Tokairin T, Sagawa T, Sakamoto T, Ito K, Kuwano K, and Makimura K

Subjects
Amphotericin B administration & dosage, Amphotericin B therapeutic use, Anti-Bacterial Agents therapeutic use, Epidural Abscess complications, Humans, Male, Middle Aged, Mycoses complications, Paranasal Sinuses diagnostic imaging, Schizophyllum drug effects, Schizophyllum genetics, Sinusitis diagnosis, Sinusitis drug therapy, Sinusitis microbiology, Skull diagnostic imaging, Skull microbiology, Tomography Scanners, X-Ray Computed, Treatment Outcome, Epidural Abscess microbiology, Mycoses microbiology, Paranasal Sinuses microbiology, Schizophyllum isolation & purification
Abstract

Central nervous system (CNS) infections due to filamentous basidiomycetes are extremely rare. We encountered a case of epidural abscess due to Schizophyllum commune that extended from sinusitis. A 53-year-old Japanese man presented at our hospital with a headache. Computed tomography (CT) of the cranium and sinuses showed ethmoid and sphenoid sinusitis with no intracranial abnormalities. The patient was diagnosed with acute sinusitis and underwent antibiotic treatment. However, the symptoms deteriorated, and the patient came to our hospital again with consciousness disturbance. CT scan of the cranium and sinuses showed no improvement of sinusitis after antibiotic therapy and an epidural abscess emerged in the middle cranial fossa. Therefore, emergency craniotomy and endoscopic sinus fenestration were performed. Filamentous fungal elements were observed in both rhinorrhoea and epidural abscess. The symptoms improved after the operation and administration of liposomal amphotericin B. The clinical isolate was identified as S. commune by a molecular-based method. To our knowledge, this is the first report of epidural abscess due to this fungus. Although rare, clinicians should be aware that S. commune could be a causative agent of CNS infections., (© 2017 Blackwell Verlag GmbH.)

Published
2018
Full Text
View/download PDF

2. Fungal keratitis due to Schizophyllum commune: an emerging pathogenic fungus.

Author

Reddy AK, Ashok R, Majety M, Chitta M, and Narayen N

Subjects
Adult, Antifungal Agents administration & dosage, Cornea microbiology, Eye Infections, Fungal drug therapy, Female, Humans, Keratitis drug therapy, Male, Middle Aged, Natamycin administration & dosage, Retrospective Studies, Schizophyllum drug effects, Schizophyllum genetics, Schizophyllum physiology, Eye Infections, Fungal microbiology, Keratitis microbiology, Schizophyllum isolation & purification
Abstract

Fungal keratitis due to Schizophyllum commune is very rare. In this study, we report the clinical and microbiological profile of five patients with fungal keratitis due to S. commune. Direct microscopic examination of corneal scrapings from all five patients showed septate branching hyaline fungal filaments. Similarly, in all five patients Sabouraud dextrose agar (SDA) plates inoculated with corneal scrapings showed white, cottony colonies on the second day of incubation. Lactophenol cotton blue stained wet preparation of 7-day-old colonies on SDA revealed clamp connections and no spores. The fungus was identified by its characteristic clamp connections, fan-shaped bracket fruiting body with pinkish-grey longitudinally split-radiating gills. The phenotypic identification of one of the five isolates further conformed by ITS sequencing. Treatment outcome was available for two of the five patients; in these two patients, the keratitis resolved with topical natamycin., (© 2016 Blackwell Verlag GmbH.)

Published
2016
Full Text
View/download PDF

3. Sinusitis and frontal brain abscess in a diabetic patient caused by the basidiomycete Schizophyllum commune: case report and review of the literature.

Author

Hoenigl M, Aspeck E, Valentin T, Heiling B, Seeber K, Krause R, Stammberger H, Beham A, and Buzina W

Subjects
Amphotericin B pharmacology, Amphotericin B therapeutic use, Antifungal Agents pharmacology, Antifungal Agents therapeutic use, Brain diagnostic imaging, Brain microbiology, Brain Abscess drug therapy, DNA, Fungal genetics, Frontal Sinusitis surgery, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Mycoses diagnosis, Mycoses drug therapy, Mycoses microbiology, Radiography, Schizophyllum drug effects, Schizophyllum genetics, Brain Abscess microbiology, Diabetes Mellitus pathology, Frontal Sinusitis microbiology, Schizophyllum isolation & purification
Published
2013
Full Text
View/download PDF

4. Schizophyllum commune as an emerging fungal pathogen: a review and report of two cases.

Author

Chowdhary A, Randhawa HS, Gaur SN, Agarwal K, Kathuria S, Roy P, Klaassen CH, and Meis JF

Subjects
Adult, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunodiffusion, Immunoglobulin E blood, Male, Microbial Sensitivity Tests, Schizophyllum drug effects, Schizophyllum pathogenicity, Skin Tests, Lung Diseases, Fungal microbiology, Schizophyllum isolation & purification
Abstract

We report Schizophyllum commune as the aetiological agent of one case each of allergic broncho-pulmonary mycosis (ABPM) and pulmonary fungal ball, and present a literature review. The fungus was characterised by clamp connections, hyphal spicules, and formation of basidiocarps with basidiospores. The phenotypic identification was confirmed by sequencing of the ITS region. To-date, ABPM and pulmonary fungal ball to S. commune have been reported exclusively from Japan and North America respectively. Of the 71 globally reported cases due to S. commune, 45 (63%) were bronchopulmonary, 22 (31%) sinusitis and 4 extrapulmonary. Taken together, cases of bronchopulmonary disease and sinusitis numbered 67 (94%), indicating the respiratory tract as the primary target of disease. Concerning the country-wise distribution, Japan topped the list with 33 cases (46%), followed by Iran - 7 cases (10%), U.S.A. - 6 cases (9%), and a lower prevalence of 1.4-6% for the remaining 12 countries. The preponderance of the disease in Japan may be attributed to its greater awareness vis-à-vis that in other countries rather than to any geographical/climatic factors. We believe that the burden of S. commune-incited disease is currently underestimated, warranting comprehensive prospective studies to determine its prevalence., (© 2012 Blackwell Verlag GmbH.)

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results