Search

Your search keyword '"Neutrophil apoptosis"' showing total 2 results
Start Over Descriptor "Neutrophil apoptosis" Journal mycologia
2 results on '"Neutrophil apoptosis"'

1. Galactosaminogalactan of Aspergillus fumigatus, a bioactive fungal polymer.

Author

Briard, Benoit, Muszkieta, Laetitia, Latgé, Jean-Paul, and Fontaine, Thierry

Subjects
*GALACTOSAMINE, *POLYSACCHARIDES, *ASPERGILLUS fumigatus, *BIOSYNTHESIS, *IMMUNOREGULATION, *NEUTROPENIA
Abstract

Galactosaminogalactan (GAG) is an extracellular polysaccharide produced by the mycelium of the opportunistic human fungal pathogen Aspergillus fumigatus. GAG is the first polysaccharide described as a virulence factor in medical mycology. This review presents our current knowledge of the structural organization and biosynthesis of this polymer. The function of this molecule as an adhesin that also masks Aspergillus PAMPs and the impact of GAG on the modulation of the host immune response by inducing neutropenia and blocking the IL-1 signaling pathway also will be emphasised. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

2. Galactosaminogalactan ofAspergillus fumigatus, a bioactive fungal polymer

Author

Jean-Paul Latgé, Benoit Briard, Laetitia Muszkieta, Thierry Fontaine, Aspergillus, Institut Pasteur [Paris], and Institut Pasteur [Paris] (IP)

Subjects
0301 basic medicine, Physiology, [SDV]Life Sciences [q-bio], Galactosaminogalactan, virulence factor, Virulence factor, Microbiology, Aspergillus fumigatus, Fungal Proteins, 03 medical and health sciences, chemistry.chemical_compound, Biopolymers, Immune system, Polysaccharides, neutrophil apoptosis, Genetics, Animals, Aspergillosis, Humans, MESH: Animals, MESH: Aspergillosis, Molecular Biology, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Ecology, Evolution, Behavior and Systematics, Mycelium, Fungal protein, Aspergillus, MESH: Humans, biology, Cell Biology, General Medicine, biology.organism_classification, galactosaminogalactan, Bacterial adhesin, MESH: Biopolymers, IL-1Ra, MESH: Polysaccharides, 030104 developmental biology, chemistry, MESH: Fungal Proteins, MESH: Aspergillus fumigatus
Abstract

International audience; Galactosaminogalactan (GAG) is an extracellular polysaccharide produced by the mycelium of the opportunistic human fungal pathogen Aspergillus fumigatus GAG is the first polysaccharide described as a virulence factor in medical mycology. This review presents our current knowledge of the structural organization and biosynthesis of this polymer. The function of this molecule as an adhesin that also masks Aspergillus PAMPs and the impact of GAG on the modulation of the host immune response by inducing neutropenia and blocking the IL-1 signaling pathway also will be emphasised.

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results