1. Loss of appetite in amyotrophic lateral sclerosis is associated with weight loss and decreased calorie consumption independent of dysphagia
- Author
-
Emily Belt, Mark Levine-Weinberg, Jamie Garry, Paige Nalipinski, Taylor Mezoian, James Chan, Christopher T. Breen, Anne-Marie Wills, Stacey Sullivan, Jane Hubbard, and Leah Miller
- Subjects
0301 basic medicine ,Male ,medicine.medical_specialty ,Calorie ,Physiology ,media_common.quotation_subject ,Nutritional Status ,030105 genetics & heredity ,Gastroenterology ,Feeding and Eating Disorders ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,0302 clinical medicine ,Weight loss ,Physiology (medical) ,Internal medicine ,Surveys and Questionnaires ,Weight Loss ,Medicine ,Humans ,Amyotrophic lateral sclerosis ,media_common ,Aged ,business.industry ,Dietary intake ,Amyotrophic Lateral Sclerosis ,Appetite ,Middle Aged ,medicine.disease ,Dysphagia ,Calorie intake ,Diet ,Measure outcomes ,Female ,Neurology (clinical) ,medicine.symptom ,business ,Deglutition Disorders ,Energy Intake ,030217 neurology & neurosurgery - Abstract
BACKGROUND Loss of appetite has been reported to affect up to half of people with amyotrophic lateral sclerosis (ALS) and to be associated with weight loss. We wished to test whether loss of appetite correlates with reduced dietary intake independent of dysphagia. METHODS Appetite was measured repeatedly using the Council on Nutrition Appetite Questionnaire (CNAQ) in participants in the Electronic health Application To Measure Outcomes REmotely study. Dietary intake and weight were compared to appetite, ALS Functional Rating Scale-Revised total and bulbar scores (dysphagia). RESULTS The average baseline CNAQ score was 30.4 (n = 61; SD = 3.9) with 18.0% scoring
- Published
- 2019