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10 results on '"Zabalza, Ana"'

1. Prediction of disease activity and treatment failure in relapsing–remitting MS patients initiating daily oral DMTs

Author

Pappolla, Agustin, primary, Auger, Cristina, additional, Sao-Aviles, Augusto, additional, Tur, Carmen, additional, Rodriguez-Barranco, Marta, additional, Cobo-Calvo, Álvaro, additional, Mongay-Ochoa, Neus, additional, Rodríguez-Acevedo, Breogán, additional, Zabalza, Ana, additional, Midaglia, Luciana, additional, Carbonell-Mirabent, Pere, additional, Carvajal, Rene, additional, Castilló-Justribó, Joaquín, additional, Braga, Nathane, additional, Bollo, Luca, additional, Vidal-Jordana, Angela, additional, Arrambide, Georgina, additional, Nos, Carlos, additional, Salerno, Annalaura, additional, Galán, Ingrid, additional, Comabella, Manuel, additional, Sastre-Garriga, Jaume, additional, Tintoré, Mar, additional, Rovira, Alex, additional, Montalban, Xavier, additional, and Río, Jordi, additional

Published
2024
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2. A wearable device perspective on the standard definitions of disability progression in multiple sclerosis

Author

Dalla Costa, Gloria, primary, Nos, Carlos, additional, Zabalza, Ana, additional, Buron, Mathias, additional, Magyari, Melinda, additional, Sellebjerg, Finn, additional, Guerrero, Ana Isabel, additional, Roselli, Lucia, additional, La Porta, Maria Libera, additional, Martinis, Matteo, additional, Bailon, Raquel, additional, Kontaxis, Spyridon, additional, Laporta, Estela, additional, Garcia, Esther, additional, Pokorny, Florian B, additional, Schuller, Björn W, additional, Folarin, Amos, additional, Stewart, Callum, additional, Leocani, Letizia, additional, Vairavan, Srinivasan, additional, Cummins, Nicholas, additional, Dobson, Richard, additional, Hotopf, Matthew, additional, Narayan, Vaibhav, additional, Montalban, Xavier, additional, Sorensen, Per Soelberg, additional, and Comi, Giancarlo, additional

Published
2023
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3. A single-dose strategy for immunization with live attenuated vaccines is an effective option before treatment initiation in multiple sclerosis patients

Author

Carvajal, René, primary, Tur, Carmen, additional, Martínez-Gómez, Xavier, additional, Bollo, Luca, additional, Esperalba, Juliana, additional, Rodriguez, Marta, additional, Pappolla, Agustín, additional, Cobo-Calvo, Alvaro, additional, Carbonell, Pere, additional, Borras-Bemejo, Blanca, additional, Río, Jordi, additional, Castilló, Joaquín, additional, Braga, Nathane, additional, Mongay-Ochoa, Neus, additional, Rodrigo-Pendás, José Ángel, additional, Vidal-Jordana, Ángela, additional, Arrambide, Georgina, additional, Rodríguez-Acevedo, Breogán, additional, Zabalza, Ana, additional, Midaglia, Luciana, additional, Galán, Ingrid, additional, Comabella, Manuel, additional, Sastre-Garriga, Jaume, additional, Montalban, Xavier, additional, Tintoré, Mar, additional, and Otero-Romero, Susana, additional

Published
2023
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4. A wearable device perspective on the standard definitions of disability progression in multiple sclerosis.

Author

Dalla Costa, Gloria, Nos, Carlos, Zabalza, Ana, Buron, Mathias, Magyari, Melinda, Sellebjerg, Finn, Guerrero, Ana Isabel, Roselli, Lucia, La Porta, Maria Libera, Martinis, Matteo, Bailon, Raquel, Kontaxis, Spyridon, Laporta, Estela, Garcia, Esther, Pokorny, Florian B, Schuller, Björn W, Folarin, Amos, Stewart, Callum, Leocani, Letizia, and Vairavan, Srinivasan

Subjects
MULTIPLE sclerosis, DISABILITIES, CENTRAL nervous system diseases, YOUNG adults
Abstract

Introduction: Multiple sclerosis (MS) is a leading cause of disability among young adults, but standard clinical scales may not accurately detect subtle changes in disability occurring between visits. This study aims to explore whether wearable device data provides more granular and objective measures of disability progression in MS. Methods: Remote Assessment of Disease and Relapse in Central Nervous System Disorders (RADAR-CNS) is a longitudinal multicenter observational study in which 400 MS patients have been recruited since June 2018 and prospectively followed up for 24 months. Monitoring of patients included standard clinical visits with assessment of disability through use of the Expanded Disability Status Scale (EDSS), 6-minute walking test (6MWT) and timed 25-foot walk (T25FW), as well as remote monitoring through the use of a Fitbit. Results: Among the 306 patients who completed the study (mean age, 45.6 years; females 67%), confirmed disability progression defined by the EDSS was observed in 74 patients, who had approximately 1392 fewer daily steps than patients without disability progression. However, the decrease in the number of steps experienced over time by patients with EDSS progression and stable patients was not significantly different. Similar results were obtained with disability progression defined by the 6MWT and the T25FW. Conclusion: The use of continuous activity monitoring holds great promise as a sensitive and ecologically valid measure of disability progression in MS. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Is humoral and cellular response to SARS-CoV-2 vaccine modified by DMT in patients with multiple sclerosis and other autoimmune diseases?

Author

Zabalza, Ana, primary, Arrambide, Georgina, additional, Otero-Romero, Susana, additional, Pappolla, Agustín, additional, Tagliani, Paula, additional, López-Maza, Samuel, additional, Cárdenas-Robledo, Simón, additional, Esperalba, Juliana, additional, Fernández-Naval, Candela, additional, Martínez-Gallo, Monica, additional, Castillo, Mireia, additional, Bonastre, Mercè, additional, Resina-Salles, Mireia, additional, Bertran, Jordina, additional, Rodriguez-Barranco, Marta, additional, Carbonell-Mirabent, Pere, additional, Gonzalez, Marina, additional, Merchan, Miguel, additional, Quiroga-Varela, Ana, additional, Miguela, Albert, additional, Gómez, Imma, additional, Álvarez, Gary, additional, Robles, René, additional, Perez del Campo, Dúnia, additional, Queralt, Xavier, additional, Soler, Maria José, additional, Agraz, Irene, additional, Martinez-Valle, Fernando, additional, Rodríguez-Acevedo, Breogán, additional, Midaglia, Luciana, additional, Vidal-Jordana, Ángela, additional, Cobo-Calvo, Álvaro, additional, Tur, Carmen, additional, Galan, Ingrid, additional, Castillo, Joaquín, additional, Río, Jordi, additional, Espejo, Carmen, additional, Comabella, Manuel, additional, Nos, Carlos, additional, Sastre-Garriga, Jaume, additional, Ramió-Torrentà, Lluís, additional, Tintoré, Mar, additional, and Montalban, Xavier, additional

Published
2022
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7. Immunoglobulin G immune response to SARS-CoV-2 vaccination in people living with multiple sclerosis within Multiple Sclerosis Partners Advancing Technology and Health Solutions

Author

Cohen, Jeffrey A, primary, Bermel, Robert A, additional, Grossman, Cynthia I, additional, Hersh, Carrie M, additional, Hyland, Megan, additional, Mowry, Ellen M, additional, Naismith, Robert, additional, Naylor, Maria L, additional, Nicholas, Jacqueline, additional, Rajbhandar, Rajani, additional, Singh, Carol M, additional, Tintorè, Mar, additional, Zabalza, Ana, additional, Ziemssen, Tjalf, additional, Williams, James R, additional, and Montalban, Xavier, additional

Published
2022
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8. Multiple sclerosis management during the COVID-19 pandemic

Author

Moss, Brandon P, primary, Mahajan, Kedar R, additional, Bermel, Robert A, additional, Hellisz, Kelsey, additional, Hua, Le H, additional, Hudec, Timothy, additional, Husak, Scott, additional, McGinley, Marisa P, additional, Ontaneda, Daniel, additional, Wang, Zhini, additional, Weber, Malory, additional, Tagliani, Paula, additional, Cárdenas-Robledo, Simón, additional, Zabalza, Ana, additional, Arrambide, Georgina, additional, Carbonell-Mirabent, Pere, additional, Rodríguez-Barranco, Marta, additional, Sastre-Garriga, Jaume, additional, Tintore, Mar, additional, Montalban, Xavier, additional, Douglas, Morgan, additional, Ogbuokiri, Esther, additional, Aravidis, Berna, additional, Cohen, Jeffrey A, additional, Mowry, Ellen M, additional, and Fitzgerald, Kathryn C, additional

Published
2020
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9. The long-term outcomes of CIS patients in the Barcelona inception cohort: Looking back to recognize aggressive MS

Author

Tintore, Mar, primary, Arrambide, Georgina, additional, Otero-Romero, Susana, additional, Carbonell-Mirabent, Pere, additional, Río, Jordi, additional, Tur, Carmen, additional, Comabella, Manuel, additional, Nos, Carlos, additional, Arévalo, María Jesús, additional, Anglada, Elisenda, additional, Menendez, Rebeca, additional, Midaglia, Luciana, additional, Galán, Ingrid, additional, Vidal-Jordana, Angela, additional, Castilló, Joaquin, additional, Mulero, Patricia, additional, Zabalza, Ana, additional, Rodríguez-Acevedo, Breogan, additional, Rodriguez, Marta, additional, Espejo, Carmen, additional, Sequeira, Joao, additional, Mitjana, Raquel, additional, de Barros, Andrea, additional, Pareto, Deborah, additional, Auger, Cristina, additional, Pérez-Hoyos, Santiago, additional, Sastre-Garriga, Jaume, additional, Rovira, Alex, additional, and Montalban, Xavier, additional

Published
2019
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10. The long-term outcomes of CIS patients in the Barcelona inception cohort: Looking back to recognize aggressive MS.

Author

Tintore, Mar, Arrambide, Georgina, Otero-Romero, Susana, Carbonell-Mirabent, Pere, Río, Jordi, Tur, Carmen, Comabella, Manuel, Nos, Carlos, Arévalo, María Jesús, Anglada, Elisenda, Menendez, Rebeca, Midaglia, Luciana, Galán, Ingrid, Vidal-Jordana, Angela, Castilló, Joaquin, Mulero, Patricia, Zabalza, Ana, Rodríguez-Acevedo, Breogan, Rodriguez, Marta, and Espejo, Carmen

Subjects
MAGNETIC resonance imaging, STANDARD deviations, MULTIPLE sclerosis
Abstract

Objective: To explore the long-term outcomes of patients with clinically isolated syndromes from the Barcelona cohort. Methods: We selected patients with a follow-up longer than 10 years to (1) estimate the risks of multiple sclerosis (MS) and disability accumulation according to the baseline number of T2 lesions and to compare treated versus untreated patients and early versus delayed treatment, and (2) to study baseline features of patients with aggressive MS (Expanded Disability Status Scale (EDSS) ⩾6.0 at 10 years). Results: In all, 401 patients were included (mean follow-up of 14.4 (standard deviation of 2.9) years). A higher number of T2 lesions was associated with an earlier MS diagnosis and an earlier risk of irreversible disability. Early treatment was associated with a decreased risk of EDSS of 3.0: adjusted hazard ratio = 0.4, 95% confidence interval = (0.2, 0.7). Patients with aggressive MS differed in their baseline brain magnetic resonance images: The median (interquartile range) number of T2 lesions and contrast-enhancing lesions (CEL) was 71 (28–95) versus 7 (1–19) and 3 (1–24) versus 0 (0–1), respectively. The cut-offs that better classified patients with aggressive MS were 20 for T2 lesions and 2 for CEL. Conclusion: Although MS natural history is changing, a high lesion load at onset is helpful to identify patients at risk of presenting an aggressive MS. [ABSTRACT FROM AUTHOR]

Published
2020
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