1. Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials
- Author
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Massimiliano Galdiero, Francisco Javier de la Mata, Sandra García-Gallego, Annarita Falanga, Gianluigi Franci, Stefania Galdiero, Veronica Folliero, Rafael Piqueras Gómez, García-Gallego, Sandra, Franci, Gianluigi, Falanga, Annarita, Gómez, Rafael, Folliero, Veronica, Galdiero, Stefania, De La Mata, Francisco Javier, Galdiero, Massimiliano, GarcÃa-Gallego, Sandra, Gã³mez, Rafael, and Universidad de Alcalá. Departamento de Química Orgánica y Química Inorgánica
- Subjects
Antiparasitic ,antiparasitic ,Computer science ,media_common.quotation_subject ,Pharmaceutical Science ,Nanotechnology ,Review ,02 engineering and technology ,010402 general chemistry ,Antiviral Agents ,01 natural sciences ,dendrimers ,Analytical Chemistry ,lcsh:QD241-441 ,lcsh:Organic chemistry ,Anti-Infective Agents ,Dendrimer ,Drug Discovery ,structure ,Antiviral ,Physical and Theoretical Chemistry ,Function (engineering) ,Biomedicine ,media_common ,preparation ,business.industry ,Medicine (all) ,Organic Chemistry ,Structure ,Química ,021001 nanoscience & nanotechnology ,antiviral ,Anti-Bacterial Agents ,Nanostructures ,0104 chemical sciences ,Antibacterial ,antibacterial ,Chemistry ,Chemistry (miscellaneous) ,Preparation ,antimicrobial ,Molecular Medicine ,Antimicrobial ,delivery ,0210 nano-technology ,business ,Delivery - Abstract
In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials.
- Published
- 2017
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