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35 results on '"PROTAC"'

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1. Stability Evaluation and Pharmacokinetic Profiling of Vepdegestrant in Rodents Using Liquid Chromatography–Tandem Mass Spectrometry.

2. Targeting Moonlighting Enzymes in Cancer.

3. Stability Evaluation and Pharmacokinetic Profiling of Vepdegestrant in Rodents Using Liquid Chromatography–Tandem Mass Spectrometry

4. Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity.

5. Targeting Moonlighting Enzymes in Cancer

6. PROTACs in the Management of Prostate Cancer.

7. In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor.

8. Current Challenges in Small Molecule Proximity-Inducing Compound Development for Targeted Protein Degradation Using the Ubiquitin Proteasomal System.

9. Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity

10. Recent Advances in Natural Product-Based Hybrids as Anti-Cancer Agents.

11. Discovery of E3 Ligase Ligands for Target Protein Degradation.

12. PROTACs in the Management of Prostate Cancer

13. Rational Design and Synthesis of HSF1-PROTACs for Anticancer Drug Development.

14. Current Challenges in Small Molecule Proximity-Inducing Compound Development for Targeted Protein Degradation Using the Ubiquitin Proteasomal System

15. Discovery of E3 Ligase Ligands for Target Protein Degradation

16. Recent Advances in Natural Product-Based Hybrids as Anti-Cancer Agents

17. Rational Design and Synthesis of HSF1-PROTACs for Anticancer Drug Development

18. Drug Discovery Targeting Focal Adhesion Kinase (FAK) as a Promising Cancer Therapy

19. Chemical Degradation of Androgen Receptor (AR) Using Bicalutamide Analog–Thalidomide PROTACs

20. PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery

21. The Potential of Proteolytic Chimeras as Pharmacological Tools and Therapeutic Agents

22. In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor

23. Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation

24. Chemical Degradation of Androgen Receptor (AR) Using Bicalutamide Analog—Thalidomide PROTACs

25. Targeting Toxins toward Tumors

26. Bifunctional HDAC Therapeutics: One Drug to Rule Them All?

27. Impact of Cross-Coupling Reactions in Drug Discovery and Development

28. Drug Discovery Targeting Focal Adhesion Kinase (FAK) as a Promising Cancer Therapy.

29. Chemical Degradation of Androgen Receptor (AR) Using Bicalutamide Analog–Thalidomide PROTACs.

30. Targeting Toxins toward Tumors.

31. PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery.

32. The Potential of Proteolytic Chimeras as Pharmacological Tools and Therapeutic Agents.

33. Bifunctional HDAC Therapeutics: One Drug to Rule Them All?

34. Impact of Cross-Coupling Reactions in Drug Discovery and Development.

35. Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation.

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