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5 results on '"Jiao Yin"'

1. Meroterpenoids from the Fungus Ganoderma sinensis and First Absolute Configuration Clarification of Zizhine H

Author

Jiao-Jiao Zhang, Bin Qiu, Yan-Jiao Yin, Yong-Xian Cheng, Dan Cai, Dan-Ling Huang, Shao-Xiang Wang, and Da-Peng Qin

Subjects
Stereochemistry, Cell Survival, meroterpenoids, Ganoderma sinensis, Pharmaceutical Science, Antineoplastic Agents, Fungus, ganoderma sinensis, zizhines p-s and u, 01 natural sciences, High-performance liquid chromatography, Article, Analytical Chemistry, lcsh:QD241-441, lcsh:Organic chemistry, Cell Line, Tumor, Drug Discovery, Ic50 values, Humans, Physical and Theoretical Chemistry, Biological evaluation, cytotoxic activity, biology, Molecular Structure, 010405 organic chemistry, Chemistry, Terpenes, Organic Chemistry, fungus, Absolute configuration, Chiral phase, Ganoderma, Fibroblasts, biology.organism_classification, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Chemistry (miscellaneous), A549 Cells, Molecular Medicine, Human cancer
Abstract

Five new meroterpenoids, zizhines P-S and U (1&minus, 4,7), together with two known meroterpenoids (5 and 6) were isolated from Ganoderma sinensis. Their structures including absolute configurations were assigned by using spectroscopic, computational, and chemical methods. Racemics zizhines P and Q were purified by HPLC on chiral phase. Biological evaluation found that 4, 5 and 6 are cytotoxic toward human cancer cells (A549, BGC-823, Kyse30) with IC50 values in the range of 63.43&ndash, 80.83 &mu, M towards A549, 59.2 &plusmn, 2.73 &mu, M and 64.25 &plusmn, 0.37 &mu, M towards BGC-823, 76.28 &plusmn, 1.93 &mu, M and 85.42 &plusmn, 2.82 &mu, M towards Kyse30.

Published
2019

2. Effects of Essential Oils from Zingiberaceae Plants on Root-Rot Disease of Panax notoginseng

Author

Chuan-Jiao Chen, Yu-Nan Ma, Wu-Mei Sun, Yong-Xian Cheng, Yan-Jiao Yin, Fu-Rong Xu, and Xian Dong

Subjects
0301 basic medicine, Antifungal, medicine.drug_class, Pharmaceutical Science, Panax notoginseng, Biology, Amomum, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, Linalool, lcsh:Organic chemistry, Zingiberaceae, Drug Discovery, medicine, Root rot, Physical and Theoretical Chemistry, essential oils, Traditional medicine, root-rot disease, fungi, Organic Chemistry, biology.organism_classification, Alpinia officinarum Hance, 030104 developmental biology, Eucalyptol, chemistry, Chemistry (miscellaneous), Molecular Medicine
Abstract

Replanting obstacles of Panax notoginseng caused by complex factors, including pathogens, have received great attention. In this study, essential oils (EOs) from either Alpinia officinarum Hance or Amomum tsao-ko (Zingiberaceae) were found to inhibit the growth of P. notoginseng-associated pathogenic fungi in vitro. Subsequent GC-MS analysis revealed the chemical profiles of two plant derived EOs. Linalool and eucalyptol were found to be abundant in the EOs and tested for their antifungal activities. In addition, the synergistic effects of A. tsao-ko EOs and hymexazol were also examined. These findings suggested that Zingiberaceae EOs might be a good source for developing new green natural pesticides fighting against root-rot of P. notoginseng.

Published
2018

4. Meroterpenoids from the Fungus Ganoderma sinensis and First Absolute Configuration Clarification of Zizhine H

Author

Yan-Jiao Yin, Dan-Ling Huang, Bin Qiu, Dan Cai, Jiao-Jiao Zhang, Shao-Xiang Wang, Da-Peng Qin, and Yong-Xian Cheng

Subjects
ganoderma sinensis, fungus, meroterpenoids, zizhines p-s and u, cytotoxic activity, Organic chemistry, QD241-441
Abstract

Five new meroterpenoids, zizhines P-S and U (1−4,7), together with two known meroterpenoids (5 and 6) were isolated from Ganoderma sinensis. Their structures including absolute configurations were assigned by using spectroscopic, computational, and chemical methods. Racemics zizhines P and Q were purified by HPLC on chiral phase. Biological evaluation found that 4, 5 and 6 are cytotoxic toward human cancer cells (A549, BGC-823, Kyse30) with IC50 values in the range of 63.43−80.83 μM towards A549, 59.2 ± 2.73 μM and 64.25 ± 0.37 μM towards BGC-823, 76.28 ± 1.93 μM and 85.42 ± 2.82 μM towards Kyse30.

Published
2019
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5. Effects of Essential Oils from Zingiberaceae Plants on Root-Rot Disease of Panax notoginseng

Author

Wu-Mei Sun, Yu-Nan Ma, Yan-Jiao Yin, Chuan-Jiao Chen, Fu-Rong Xu, Xian Dong, and Yong-Xian Cheng

Subjects
Zingiberaceae, Panax notoginseng, root-rot disease, fungi, essential oils, Organic chemistry, QD241-441
Abstract

Replanting obstacles of Panax notoginseng caused by complex factors, including pathogens, have received great attention. In this study, essential oils (EOs) from either Alpinia officinarum Hance or Amomum tsao-ko (Zingiberaceae) were found to inhibit the growth of P. notoginseng-associated pathogenic fungi in vitro. Subsequent GC-MS analysis revealed the chemical profiles of two plant derived EOs. Linalool and eucalyptol were found to be abundant in the EOs and tested for their antifungal activities. In addition, the synergistic effects of A. tsao-ko EOs and hymexazol were also examined. These findings suggested that Zingiberaceae EOs might be a good source for developing new green natural pesticides fighting against root-rot of P. notoginseng.

Published
2018
Full Text
View/download PDF

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