Search

Your search keyword '"O'Brien, Cathal"' showing total 3 results
Start Over Author "O'Brien, Cathal" Journal molecular diagnosis & therapy
3 results on '"O'Brien, Cathal"'

3. Predictive Values for Molecular Diagnostics: Converting Unknown Unknowns to Known Unknowns.

Author

O'Brien, Cathal, Langabeer, Stephen, O'Byrne, Kenneth, O'Leary, John, and Finn, Stephen

Subjects
*MOLECULAR diagnosis, *GENETIC mutation measurement, *GENETIC mutation, *DISEASE prevalence, *ONCOLOGY research, *PREDICTIVE tests, *CHARTS, diagrams, etc.
Abstract

The authors focus on the recent advancements in molecular diagnostics for predictive mutation testing in the field of oncology and pathology. Topics discussed include mathematical approach for the calculation of predictive value of a molecular assay, mutation testing of BRAF gene and mechanism involved in epidermal growth factor receptor signaling pathway. A diagram illustrating the effect of disease prevalence and assay sensitivity and specificity is presented.

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results