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Your search keyword '"Lanzer, Michael"' showing total 11 results
Start Over Author "Lanzer, Michael" Journal molecular and biochemical parasitology
11 results on '"Lanzer, Michael"'

8. Characterization and cloning of the gene encoding the vacuolar membrane protein EXP-2 from Plasmodium falciparum1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBank™ and DDJB databases under the accession number AJ000652.1

Author

Fischer, Katja, primary, Marti, Thomas, additional, Rick, Barbara, additional, Johnson, Delia, additional, Benting, Jürgen, additional, Baumeister, Stefan, additional, Helmbrecht, Claudia, additional, Lanzer, Michael, additional, and Lingelbach, Klaus, additional

Published
1998
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9. Current status of the Plasmodium falciparum genome project

Author

Dame, John B., primary, Arnot, David E., additional, Bourke, Peter F., additional, Chakrabarti, Debopam, additional, Christodoulou, Zoe, additional, Coppel, Ross L., additional, Cowman, Alan F., additional, Craig, Alister G., additional, Fischer, Katja, additional, Foster, Jeremy, additional, Goodman, Nathan, additional, Hinterberg, Katherine, additional, Holder, Anthony A., additional, Holt, Deborah C., additional, Kemp, David J., additional, Lanzer, Michael, additional, Lim, Amanda, additional, Newbold, Chris I., additional, Ravetch, Jeffery V., additional, Reddy, G.Roman, additional, Rubio, Justin, additional, Schuster, Sheldon M., additional, Su, Xin-zhuan, additional, Thompson, Jennifer K., additional, Vital, Ferdinand, additional, Wellems, Thomas E., additional, and Werner, Ekkehard B., additional

Published
1996
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11. Complementation of Saccharomyces cerevisiaepik1ts by a phosphatidylinositol 4-kinase from Plasmodium falciparum.

Author

Krüger T, Sanchez CP, and Lanzer M

Subjects
Genetic Complementation Test, Hot Temperature, Mutation, Missense, Plasmodium falciparum genetics, Saccharomyces cerevisiae genetics, 1-Phosphatidylinositol 4-Kinase deficiency, 1-Phosphatidylinositol 4-Kinase genetics, Plasmodium falciparum enzymology, Protozoan Proteins genetics, Saccharomyces cerevisiae enzymology, Saccharomyces cerevisiae Proteins genetics
Abstract

Phosphoinositides comprise a group of essential phospholipids that control a variety of cellular functions. In the case of the human malaria parasite Plasmodium falciparum, phosphoinositides have been shown to trigger exflagellation and to affect haemoglobin endocytosis and maturation of the parasite's digestive vacuole. A central enzyme in the formation of phosphoinositides is the phosphatidylinositol 4-kinase that catalyzes the production of phosphatidylinositol 4-phosphate from phosphatidylinositol. Here we have identified and characterized a phosphatidylinositol 4-kinase from P. falciparum. Our data show that the corresponding P. falciparum gene, termed PFE0485w, can functionally complement a yeast temperature-sensitive pik1 mutation. Our data add to the concept that P. falciparum maintains its own phospholipids biosynthesis pathway.

Published
2010
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